71,194 research outputs found

    Hitchhiking Through the Cytoplasm

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    We propose an alternative mechanism for intracellular cargo transport which results from motor induced longitudinal fluctuations of cytoskeletal microtubules (MT). The longitudinal fluctuations combined with transient cargo binding to the MTs lead to long range transport even for cargos and vesicles having no molecular motors on them. The proposed transport mechanism, which we call ``hitchhiking'', provides a consistent explanation for the broadly observed yet still mysterious phenomenon of bidirectional transport along MTs. We show that cells exploiting the hitchhiking mechanism can effectively up- and down-regulate the transport of different vesicles by tuning their binding kinetics to characteristic MT oscillation frequencies

    Localization transitions in non-Hermitian quantum mechanics

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    We study the localization transitions which arise in both one and two dimensions when quantum mechanical particles described by a random Schr\"odinger equation are subjected to a constant imaginary vector potential. A path-integral formulation relates the transition to flux lines depinned from columnar defects by a transverse magnetic field in superconductors. The theory predicts that the transverse Meissner effect is accompanied by stretched exponential relaxation of the field into the bulk and a diverging penetration depth at the transition.Comment: 4 pages (latex) with 3 figures (epsf) embedded in the text using the style file epsf.st

    The Impact of Government Policies on Philippine Sugar

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    This paper examines the impact of trade policies, such as export taxes, marketing controls, low interest rate on production and equipment loans and special minimum wages, on sugar production and trade. It also investigates the effect of government polices on domestic prices and therefore the distribution of income from sugar production and processing.economic reform, sugar products

    Optical fiber coupling method and apparatus

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    Systems are described for coupling a pair of optical fibers to pass light between them, which enables a coupler to be easily made, and with simple equipment, while closely controlling the characteristics of the coupler. One method includes mounting a pair of optical fibers on a block having a large hole therein, so the fibers extend across the hole while lying adjacent and parallel to one another. The fibers are immersed in an etchant to reduce the thickness of cladding around the fiber core. The fibers are joined together by applying a liquid polymer so the polymer-air interface moves along the length of the fibers to bring the fibers together in a zipper-like manner, and to progressively lay a thin coating of the polymer on the fibers

    Patterned Geometries and Hydrodynamics at the Vortex Bose Glass Transition

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    Patterned irradiation of cuprate superconductors with columnar defects allows a new generation of experiments which can probe the properties of vortex liquids by confining them to controlled geometries. Here we show that an analysis of such experiments that combines an inhomogeneous Bose glass scaling theory with the hydrodynamic description of viscous flow of vortex liquids can be used to infer the critical behavior near the Bose glass transition. The shear viscosity is predicted to diverge as ∣T−TBG∣−z|T-T_{BG}|^{-z} at the Bose glass transition, with z≃6z\simeq 6 the dynamical critical exponent.Comment: 5 pages, 4 figure

    Superspace Formulation for the BRST Quantization of the Chiral Schwinger Model

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    It has recently been shown that the Field Antifield quantization of anomalous irreducible gauge theories with closed algebra can be represented in a BRST superspace where the quantum action at one loop order, including the Wess Zumino term, and the anomalies show up as components of the same superfield. We show here how the Chiral Schwinger model can be represented in this formulation.Comment: 11 pages, Late

    Understanding Extended Projected Profile (EPP) Trajectory Error Using a Medium-Fidelity Aircraft Simulation

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    A critical component of Trajectory-Based Operations is the ability for a consistent and accurate 4-dimensional trajectory to be shared and synchronized between airborne and ground systems as well as amongst various ground automation systems. The Aeronautical Telecommunication NetworkBaseline 2 standard defines the Extended Projected Profile (EPP) trajectory that can be sent via Automatic Dependent Surveillance-Contract from an aircraft to ground automation. The EPP trajectory message contains a representation of the reference trajectory from an aircrafts Flight Management System (FMS). In this work, a set of scenarios were run in a medium-fidelity aircraft and FMS simulation to perform an initial characterization of EPP trajectory errors under a given set of conditions. The parameters investigated were the route length, route type, wind magnitude error, wind direction error, and with and without a required time-of-arrival constraint

    An experimental investigation of vortex breakdown on a delta wing

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    An experimental investigation of vortex breakdown on delta wings at high angles is presented. Thin delta wings having sweep angles of 70, 75, 80 and 85 degrees are being studied. Smoke flow visualization and the laser light sheet technique are being used to obtain cross-sectional views of the leading edge vortices as they break down. At low tunnel speeds (as low as 3 m/s) details of the flow, which are usually imperceptible or blurred at higher speeds, can be clearly seen. A combination of lateral and longitudinal cross-sectional views provides information on the three dimensional nature of the vortex structure before, during and after breakdown. Whereas details of the flow are identified in still photographs, the dynamic characteristics of the breakdown process were recorded using high speed movies. Velocity measurements were obtained using a laser Doppler anemometer with the 70 degree delta wing at 30 degrees angle of attack. The measurements show that when breakdown occurs the core flow transforms from a jet-like flow to a wake-like flow
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