56 research outputs found
ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in wistar rats
We investigated the influence of bone marrow cells upon activation of ERK œ in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation
Utilização do perfluorocarbono lĂquido na preservação de enxertos pulmonares submetidos a diferentes perĂodos de isquemia fria em modelo animal
A influĂȘncia do tempo de isquemia sobre o estresse oxidativo em modelo isquemia e reperfusĂŁo pulmonar em ratos
Utilização do perfluorocarbono lĂquido na preservação de enxertos pulmonares submetidos a diferentes perĂodos de isquemia fria em modelo animal
MELTING CURVE ANALYSIS FOR THE SCREENING OF HEPATITIS B VIRUS GENOTYPES A, D AND F IN PATIENTS FROM A GENERAL HOSPITAL IN SOUTHERN BRAZIL
Aspectos histológicos e lipoperoxidação no intestino grosso de ratos submetidos à colite experimental e pré-tratados com glutamina
IRS1 expression in hepatic tissue and leukocytes in chronic hepatitis C virus infected patients : a comparative study
Aims. To determine lymphocyte IRS (IRS1 cells) in HCV patients, correlating it to liver IRS (IRS 1liver) and HOMA-IR. This study tested the hypothesis that IRS1 cells expression can be used as insulin resistance (IR) marker in HCV-infected patients. IRS1 cells were not studied before in HCV infection. Materials and Methods. HCV chronically infected patients, naĂŻve, nonobese, noncirrhotic, and nondiabetic were prospectively included and compared to controls (blood donors). Blood was taken, and leukocytes were separated. IRS1 was determined by real-time PCR. Liver tissue was obtained from transplant donors as controls. Results. 41 HCV-positive patients were included, 26 males (60.5%); mean age of 45 (±7.9); 33 (80.5%) from genotype 1. 6 out of 12 controls were males (50%); mean age was 26.7 (±3.2). There was expression of IRS1 in leukocytes. The median IRS1 cells (HCV) were 0.061 (0.004 to 0.469); the median IRS 1liver (HCV) was 0.0003 (0.00002 to 0.0186)âlower than in controls (resp., P = 0.005 and P = 0.018). HOMA-IR had an inverse correlation with IRS 1liver (P = 0.04). There was no correlation between IRS1 liver and IRS1 cells (P = 0.930). Conclusions. There was expression of IRS1 in leukocytes. IRS1 cells and IRS1 liver were lower in HCV patients than in controls
O uso da matriz extracelular (MEC) recelularizada como arcabouço para o estabelecimento de um fĂgado bioartificial : um modelo experimental
Avaliação da citotoxicidade do tetracloreto de carbono (CCL4) in vitro nas linhagens hepåticas HuH7 e ARL-6
O uso da matriz extracelular (MEC) recelularizada como arcabouço para o estabelecimento de um fĂgado bioartificial : um modelo experimental
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