88 research outputs found
PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens
Kepler Eclipsing Binary Stars. VI. Identification of Eclipsing Binaries in the K2 Campaign 0 Data-set
The original {\it Kepler} mission observed and characterized over 2400
eclipsing binaries in addition to its prolific exoplanet detections. Despite
the mechanical malfunction and subsequent non-recovery of two reaction wheels
used to stabilize the instrument, the {\it Kepler} satellite continues
collecting data in its repurposed {\it K2} mission surveying a series of fields
along the ecliptic plane. Here we present an analysis of the first full
baseline {\it K2} data release: the Campaign 0 data-set. In the 7761 light
curves, we have identified a total of 207 eclipsing binaries. Of these, 97 are
new discoveries that were not previously identified. Our pixel-level analysis
of these objects has also resulted in identification of several false positives
(observed targets contaminated by neighboring eclipsing binaries), as well as
the serendipitous discovery of two short period exoplanet candidates. We
provide catalog cross-matched source identifications, orbital periods,
morphologies and ephemerides for these eclipsing systems. We also describe the
incorporation of the K2 sample into the Kepler Eclipsing Binary
Catalog\footnote{\url{keplerebs.villanova.edu/k2}}, present spectroscopic
follow-up observations for a limited selection of nine systems, and discuss
prospects for upcoming {\it K2} campaigns.Comment: Accepted for publication in MNRAS. 51 pages [20 figures, 8 tables].
Results available online in the Kepler Eclipsing Binary Star Catalog
http://keplerebs.villanova.edu/k
Theoretical Considerations on the Properties of Accreting Millisecond Pulsars
We examine a number of evolutionary scenarios for the recently discovered
class of accretion-powered millisecond X-ray pulsars in ultracompact binaries,
including XTE J0929-314 and XTE J1751-305, with orbital periods of 43.6 and
42.4 minutes, respectively. We focus on a particular scenario that can
naturally explain the present-day properties of these systems. This model
invokes a donor star that was either very close to the TAMS (i.e.,
main-sequence turnoff) at the onset of mass transfer or had sufficient time to
evolve during the mass-transfer phase. We have run a systematic set of detailed
binary evolution calculations with a wide range of initial donor masses and
degrees of (nuclear) evolution at the onset of mass transfer. In general, the
models whose evolutionary tracks result in the best fits to these ultracompact
binaries start mass transfer with orbital periods of ~15 hr, then decrease to a
minimum orbital period of less than or about 40 minutes, and finally evolve
back up to about 43 minutes. We also carry out a probability analysis based on
the measured mass functions of XTE J0929-314 and XTE J1751-305, and combine
this with the results of our binary evolution models and find that the donor
stars currently have masses in the range of about 0.012 - 0.025 solar masses,
and radii of about 0.042 - 0.055 solar radii, and that these radii are likely
to be factors of about 1.1 - 1.3 times larger than the corresponding
zero-temperature ones. We also find that the interiors of the donors are
largely composed of helium and that the surface hydrogen abundances are almost
certainly less than 10% (by mass).Comment: 16 pages, 6 figures, 3 table
The Aspen-Amsterdam void finder comparison project
Despite a history that dates back at least a quarter of a century, studies of voids in the large-scale structure of the Universe are bedevilled by a major problem: there exist a large number of quite different void-finding algorithms, a fact that has so far got in the way of groups comparing their results without worrying about whether such a comparison in fact makes sense. Because of the recent increased interest in voids, both in very large galaxy surveys and in detailed simulations of cosmic structure formation, this situation is very unfortunate. We here present the first systematic comparison study of 13 different void finders constructed using particles, haloes, and semi-analytical model galaxies extracted from a subvolume of the Millennium simulation. This study includes many groups that have studied voids over the past decade. We show their results and discuss their differences and agreements. As it turns out, the basic results of the various methods agree very well with each other in that they all locate a major void near the centre of our volume. Voids have very underdense centres, reaching below 10 per cent of the mean cosmic density. In addition, those void finders that allow for void galaxies show that those galaxies follow similar trends. For example, the overdensity of void galaxies brighter than mB=−20 is found to be smaller than about −0.8 by all our void finding algorithm
An Exploration of the Paradigm for the 2-3 Hour Period Gap in Cataclysmic Variables
We critically examine the basic paradigm for the origin of the 2-3 hr period
gap in cataclysmic variables (CVs). We carry out an extensive population
synthesis study of CVs starting from ~ 3 x 10^6 primordial binaries, and
evolving some ~ 2 x 10^4 surviving systems through their CV phase. In
particular we study current-epoch distributions of CVs in the ,
R_{2}-P_{orb}, M_{2}-P_{orb}, q-P_{orb}, T_{eff}-P_{orb}, and L_{2}-P_{orb}
planes, where is the mass transfer rate, q is the mass ratio M_2/M_1,
and M_2, R_2, T_{eff}, and L_2 are the donor star mass, radius, effective
temperature, and luminosity, respectively. This work presents a new perspective
on theoretical studies of the long-term evolution of CVs. In particular, we
show that if the current paradigm is correct, the secondary masses in CVs just
above the period gap should be as much as ~ 50% lower than would be inferred if
one assumes a main-sequence radius-mass relation for the donor star.Comment: Accepted in Ap
Lineage replacement and evolution captured by 3 years of the United Kingdom Coronavirus (COVID-19) Infection Survey
The Office for National Statistics Coronavirus (COVID-19) Infection Survey (ONS-CIS) is the largest surveillance study of SARS-CoV-2 positivity in the community, and collected data on the United Kingdom (UK) epidemic from April 2020 until March 2023 before being paused. Here, we report on the epidemiological and evolutionary dynamics of SARS-CoV-2 determined by analysing the sequenced samples collected by the ONS-CIS during this period. We observed a series of sweeps or partial sweeps, with each sweeping lineage having a distinct growth advantage compared to their predecessors, although this was also accompanied by a gradual fall in average viral burdens from June 2021 to March 2023. The sweeps also generated an alternating pattern in which most samples had either S-gene target failure (SGTF) or non-SGTF over time. Evolution was characterized by steadily increasing divergence and diversity within lineages, but with step increases in divergence associated with each sweeping major lineage. This led to a faster overall rate of evolution when measured at the between-lineage level compared to within lineages, and fluctuating levels of diversity. These observations highlight the value of viral sequencing integrated into community surveillance studies to monitor the viral epidemiology and evolution of SARS-CoV-2, and potentially other pathogens
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