194 research outputs found

    A UAV Mission Hierarchy

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    In the following sections, each of the primary missions are decomposed into mission planning, management, and replanning segments in order to identify what the primary functions a human operator will need to perform. The goal is to understand what tasks/functions are common across different UAV missions and platforms in order to map the generalizability of any particular research project.Prepared for Charles River Analytic

    CICLAD: A Fast and Memory-efficient Closed Itemset Miner for Streams

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    Mining association rules from data streams is a challenging task due to the (typically) limited resources available vs. the large size of the result. Frequent closed itemsets (FCI) enable an efficient first step, yet current FCI stream miners are not optimal on resource consumption, e.g. they store a large number of extra itemsets at an additional cost. In a search for a better storage-efficiency trade-off, we designed Ciclad,an intersection-based sliding-window FCI miner. Leveraging in-depth insights into FCI evolution, it combines minimal storage with quick access. Experimental results indicate Ciclad's memory imprint is much lower and its performances globally better than competitor methods.Comment: KDD2

    Regions of High Out-Of-Hospital Cardiac Arrest Incidence and Low Bystander CPR Rates in Victoria, Australia

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    BACKGROUND: Out-of-hospital cardiac arrest (OHCA) remains a major public health issue and research has shown that large regional variation in outcomes exists. Of the interventions associated with survival, the provision of bystander CPR is one of the most important modifiable factors. The aim of this study is to identify census areas with high incidence of OHCA and low rates of bystander CPR in Victoria, Australia. METHODS: We conducted an observational study using prospectively collected population-based OHCA data from the state of Victoria in Australia. Using ArcGIS (ArcMap 10.0), we linked the location of the arrest using the dispatch coordinates (longitude and latitude) to Victorian Local Government Areas (LGAs). We used Bayesian hierarchical models with random effects on each LGA to provide shrunken estimates of the rates of bystander CPR and the incidence rates. RESULTS: Over the study period there were 31,019 adult OHCA attended, of which 21,436 (69.1%) cases were of presumed cardiac etiology. Significant variation in the incidence of OHCA among LGAs was observed. There was a 3 fold difference in the incidence rate between the lowest and highest LGAs, ranging from 38.5 to 115.1 cases per 100,000 person-years. The overall rate of bystander CPR for bystander witnessed OHCAs was 62.4%, with the rate increasing from 56.4% in 2008-2010 to 68.6% in 2010-2013. There was a 25.1% absolute difference in bystander CPR rates between the highest and lowest LGAs. CONCLUSION: Significant regional variation in OHCA incidence and bystander CPR rates exists throughout Victoria. Regions with high incidence and low bystander CPR participation can be identified and would make suitable targets for interventions to improve CPR participation rates

    Isospin breaking in Kl4 decays

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    Data on Ke4 decays allow one to extract experimental information on the elastic pi pi scattering amplitude near threshold, and to confront the outcome of the analysis with predictions made in the framework of QCD. These predictions concern an isospin symmetric world, while experiments are carried out in the real world, where isospin breaking effects - generated by electromagnetic interactions and by the mass difference of the up and down quarks - are always present. We discuss the corrections required to account for these, so that a meaningful comparison with the predictions becomes possible. In particular, we note that there is a spectacular isospin breaking effect in Ke4 decays. Once it is taken into account, the previous discrepancy between NA48/2 data on Ke4 decays and the prediction of pi pi scattering lengths disappears.Comment: 33 pages, 12 figure

    Relative Roles of the Cellular and Humoral Responses in the Drosophila Host Defense against Three Gram-Positive Bacterial Infections

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    BACKGROUND: Two NF-kappaB signaling pathways, Toll and immune deficiency (imd), are required for survival to bacterial infections in Drosophila. In response to septic injury, these pathways mediate rapid transcriptional activation of distinct sets of effector molecules, including antimicrobial peptides, which are important components of a humoral defense response. However, it is less clear to what extent macrophage-like hemocytes contribute to host defense. METHODOLOGY/PRINCIPAL FINDINGS: In order to dissect the relative importance of humoral and cellular defenses after septic injury with three different gram-positive bacteria (Micrococcus luteus, Enterococcus faecalis, Staphylococcus aureus), we used latex bead pre-injection to ablate macrophage function in flies wildtype or mutant for various Toll and imd pathway components. We found that in all three infection models a compromised phagocytic system impaired fly survival--independently of concomitant Toll or imd pathway activation. Our data failed to confirm a role of the PGRP-SA and GNBP1 Pattern Recognition Receptors for phagocytosis of S. aureus. The Drosophila scavenger receptor Eater mediates the phagocytosis by hemocytes or S2 cells of E. faecalis and S. aureus, but not of M. luteus. In the case of M. luteus and E. faecalis, but not S. aureus, decreased survival due to defective phagocytosis could be compensated for by genetically enhancing the humoral immune response. CONCLUSIONS/SIGNIFICANCE: Our results underscore the fundamental importance of both cellular and humoral mechanisms in Drosophila immunity and shed light on the balance between these two arms of host defense depending on the invading pathogen
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