What discount rates should the Public Sector adopt in a Public-Private Partnership?

Mestrado em Ciências EmpresariaisO conceito de parcerias público - privadas tem chamado a atenção dos economistas e Governos nas últimas décadas, onde sucessos e fracassos coexistem em todo o Mundo na esperança de atingir o Value for Money. A definição, conceitos e os objectivos das parcerias público -privadas serão abordadas na generalidade da tese. A taxa de desconto que o sector público deverá adoptar numa parceria deste tipo é uma discussão global e a questão principal abordada nesta tese. Não será concluído se a parceria público - privada deveria ser ou não realizada. Há muitas perspectivas diferentes relativas às várias taxas de desconto a utilizar, mas, neste caso, apenas serão abordadas três taxas distintas e será construída e analisada uma estimativa relativa ao valor actual dos pagamentos futuros efectuados pelo Governo às empresas privadas que têm contractos no formato de parceria público - privada.The concept of Public Private Partnerships has brought attention to the economists and Public Parties on the last few decades, where success and failure have occurred all over the world, where Governments search for the objective of Value for Money. We will define what a Public Private Partnership is and what are their main goals and conceptions. What discount rate should the Public Sector adopt in a Public Private Partnership is a global discussion nowadays and the main issue on this paper. We will not consider if a Public Private Partnership should or should not be realized, on the other hand we will try to create some scenario basis for the Portuguese experience. There are many different approaches and in this paper we will take a look to three different approaches and develop an estimate through the future payments in the next 50 years of Portuguese governments' payments to the private sector

Automist - A Tool for Automated Instruction Set Characterization of Embedded Processors

The steadily increasing performance of mobile devices also implies a rise in power consumption. To counteract this trend it is mandatory to accomplish software power optimizations based on accurate power consumption models characterized for the processor. This paper presents an environment for automated instruction set characterization based on physical power measurements. Based on a detailed instruction set description a testbench generator creates all needed test programs for a complete characterization. Afterwards those programs are executed by the processor and the energy consumption is measured. For an accurate energy measurement a high performance sampling technique has been established, which can be either clock or energy driven

Probiotic Microorganisms in Dry Fermented Meat Products

In the modern lifestyle, food is supposed not only to feed the hunger but also to provide an appropriate amount and quality of nutrients necessary for proper functioning of the body. The interest of consumers in functional food, including fermented products with probiotic properties, has been growing for several years. Meat and meat products represent one of the most important components of contemporary human diet. Meat fermentation is one of the oldest methods of preserving food. This is a low‐energy, biological acidulation which results in unique flavour and palatability, colour, microbiological safety and tenderness. Changes of muscle form into fermented meat product are caused by homo‐ or heterofermentative starter cultures or “wild” microorganisms which lower the pH. Fermented meat products are one of the most cherished and valuable food products. Fermentation and ageing process would deliver most aromatic and rich in flavour products, which is incomparable with other processes. A new solution is dry‐aged meats with the use of new probiotic starter cultures with a high degree of health safety and long shelf life due to the inhibition of growth of the pathogenic microorganisms and therefore reduction of the formation of harmful compounds from protein transformation or lipid oxidation

Methodologies for Designing Power-Aware Smart Card Systems

Smart cards are some of the smallest computing platforms in use today. They have limited resources, but a huge number of functional requirements. The requirement for multi-application cards increases the demand for high performance and security even more, whereas the limits given by size and energy consumption remain constant. We describe new methodologies for designing and implementing entire systems with regard to power awareness and required performance. To make use of this power-saving potential, also the higher layers of the system - the operating system layer and the application domain layer - are required to be designed together with the rest of the system. HW/SW co-design methodologies enable the gain of system-level optimization. The first part presents the abstraction of smart cards to optimize system architecture and memory system. Both functional and transactional-level models are presented and discussed. The proposed design flow and preliminary results of the evaluation are depicted. Another central part of this methodology is a cycle-accurate instruction-set simulator for secure software development. The underlaying energy model is designed to decouple instruction and data dependent energy dissipation, which leads to an independent characterization process and allows stepwise model refinement to increase estimation accuracy. The model has been evaluated for a high-performance smart card CPU and an use-case for secure software is given

Amides as Non-polymerizable Catalytic Adjuncts Enable the Ring-Opening Polymerization of Lactide With Ferrous Acetate Under Mild Conditions

Sn-based catalysts are effective in the ring-opening polymerization (ROP) but are toxic. Fe(OAc)2 used as an alternative catalyst is suitable for the ROP of lactide only at higher temperatures (>170°C), associated with racemization. In the ROP of ester and amide group containing morpholinediones with Fe(OAc)2 to polydepsipeptides at 135°C, ester bonds were selectively opened. Here, it was hypothesized that ROP of lactones is possible with Fe(OAc)2 when amides are present in the reactions mixture as Fe-ligands could increase the solubility and activity of the metal catalytic center. The ROP of lactide in the melt with Fe(OAc)2 is possible at temperatures as low as 105°C, in the presence of N-ethylacetamide or N-methylbenzamide as non-polymerizable catalytic adjuncts (NPCA), with high conversion (up to 99 mol%) and yield (up to 88 mol%). Polydispersities of polylactide decreased with decreasing reaction temperature to ≤ 1.1. NMR as well as polarimetric studies showed that no racemization occurred at reaction temperatures ≤145°C. A kinetic study demonstrated a living chain-growth mechanism. MALDI analysis revealed that no side reactions (e.g., cyclization) occurred, though transesterification took place

Compiler-based Software Power Peak Elimination on Smart Card Systems

RF-powered smart cards are widely used in different application areas today. For smart cards not only performance is an important attribute, but also the power consumed by a given application. The power consumed is heavily depending on the software executed on the system. The power profile, especially the power peaks, of an executed application influence the system stability and security. Flattening the power profile can thus increase the stability and security of a system. In this paper we present an optimization system that allows a reduction of power peaks based on a compiler optimization. The optimizations are done on different levels of the compiler. In the backend of the compiler we present new instruction scheduling algorithms. On the intermediate language level we propose the use of iterative compiling for reducing critical peaks

Perfluorophenyl azide functionalization of electrospun poly(para‐dioxanone)

Strategies to surface‐functionalize scaffolds by covalent binding of biologically active compounds are of fundamental interest to control the interactions between scaffolds and biomolecules or cells. Poly(para‐dioxanone) (PPDO) is a clinically established polymer that has shown potential as temporary implant, eg, for the reconstruction of the inferior vena cava, as a nonwoven fiber mesh. However, PPDO lacks suitable chemical groups for covalent functionalization. Furthermore, PPDO is highly sensitive to hydrolysis, reflected by short in vivo half‐life times and degradation during storage. Establishing a method for covalent functionalization without degradation of this hydrolyzable polymer is therefore important to enable the surface tailoring for tissue engineering applications. It was hypothesized that treatment of PPDO with an N‐hydroxysuccinimide ester group bearing perfluorophenyl azide (PFPA) under UV irradiation would allow efficient surface functionalization of the scaffold. X‐ray photoelectron spectroscopy and attenuated total reflectance Fourier‐transformed infrared spectroscopy investigation revealed the successful binding, while a gel permeation chromatography study showed that degradation did not occur under these conditions. Coupling of a rhodamine dye to the N‐hydroxysuccinimide esters on the surface of a PFPA‐functionalized scaffold via its amine linker showed a homogenous staining of the PPDO in laser confocal microscopy. The PFPA method is therefore applicable even to the surface functionalization of hydrolytically labile polymers, and it was demonstrated that PFPA chemistry may serve as a versatile tool for the (bio‐)functionalization of PPDO scaffolds

Functionalizable coaxial PLLA/PDLA nanofibers with stereocomplexes at the internal interface

Multifunctionality of electrospun polylactic acid (PLA) nonwovens was generated by the morphological design of nanofibers. Coaxial fibers with a lower number average molar mass Mn PLLA core and a higher Mn PDLA shell form PDLA–PLLA stereocrystals at the interface, induced by annealing. In tensile tests under physiological conditions, the core–shell fibers with higher crystallinity (22% compared to 11–14%) had lower Young’s moduli E (9 ± 1 MPa) and lower elongation at break εb (26 ± 3%) than PDLA alone (E = 31 ± 9 MPa, εb = 80 ± 5%), which can be attributed to simultaneous crystallization and relaxation effects. Gelatin incorporated in the PDLA phase was presented on the outer surface providing a biointerface putatively favorable for cell adherence. Gelatin incorporation did not influence the crystallization behavior but slightly lowered Tg (60 → 54 °C). Employing exclusively polymers established in the clinic, multifunctionality was generated by design

RGD constructs with physical anchor groups as polymer co-electrospinnable cell adhesives

The tissue integration of synthetic polymers can be promoted by displaying RGD peptides at the biointerface with the objective of enhancing colonization of the material by endogenous cells. A firm but flexible attachment of the peptide to the polymer matrix, still allowing interaction with receptors, is therefore of interest. Here, the covalent coupling of flexible physical anchor groups, allowing for temporary immobilization on polymeric surfaces via hydrophobic or dipole–dipole interactions, to a RGD peptide was investigated. For this purpose, a stearate or an oligo(ethylene glycol) (OEG) was attached to GRGDS in 51–69% yield. The obtained RGD linker constructs were characterized by NMR, IR and MALDI-ToF mass spectrometry, revealing that the commercially available OEG and stearate linkers are in fact mixtures of similar compounds. The RGD linker constructs were co-electrospun with poly(p-dioxanone) (PPDO). After electrospinning, nitrogen could be detected on the surface of the PPDO fibers by X-ray photoelectron spectroscopy. The nitrogen content exceeded the calculated value for the homogeneous material mixture suggesting a pronounced presentation of the peptide on the fiber surface. Increasing amounts of RGD linker constructs in the electrospinning solution did not lead to a detection of an increased amount of peptide on the scaffold surface, suggesting inhomogeneous distribution of the peptide on the PPDO fiber surface. Human adipose-derived stem cells cultured on the patches showed similar viability as when cultured on PPDO containing pristine RGD. The fully characterized RGD linker constructs could serve as valuable tools for the further development of tissue-integrating polymeric scaffolds