The role of endorphins and vasopressin in canine endotoxin shock

Chemical antagonists were used to assess the role of [beta]-endorphin and arginine-vasopressin (AVP) in canine endotoxin shock. Fifteen awake dogs were given Escherichia coli endotoxin IV. Within 5 min, CO decreased to 28%, LV dP/dt to 46%, and MAP to 52% of baseline. Fifteen minutes after endotoxin, five dogs each received naloxone, AVP antagonist, or no treatment. Control (untreated) animals exhibited persistent cardiovascular depression, with CO 49%, LV dP/dt 69%, and MAP 91% of baseline after 45 min. Naloxone improved CO to 69%, LV dP/dt to 94%, and MAP to 91% by 30 min after treatment. AVP blockade improved CO to 105%, LV dP/dt to 10%, and MAP to 95% of baseline by 30 min after treatment, and caused significant tachycardia. Plasma cortisol and AVP increased markedly in all groups after endotoxin administration. AVP antagonist treatment increased mean survival from 1.4 to 4 days. These data suggest that abnormally elevated AVP contributes to cardiovascular depression in canine endotoxin shock and that AVP blockade is therapeutic in the animal model studied.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25963/1/0000029.pd

The Otterbein Miscellany - May 1968

https://digitalcommons.otterbein.edu/miscellany/1001/thumbnail.jp

The Star Formation Rate Function of the Local Universe

We have derived the bivariate luminosity function for the far ultraviolet (1530Angstroms) and far infrared (60 microns). We used matched GALEX and IRAS data, and redshifts from NED and PSC-z. We have derived a total star formation luminosity function phi(L_{tot}), with L_{tot} = L_{FUV}+L_{FIR}. Using these, we determined the cosmic ``star formation rate'' function and density for the local universe. The total SFR function is fit very well by a log-normal distribution over five decades of luminosity. We find that the bivariate luminosity function phi(L_{FUV},L_{FIR}) shows a bimodal behavior, with L_{FIR} tracking L_{FUV} for L_{TOT}< 10^10 L_sun, and L_{FUV} saturating at 10^10 L_sun, while L_{TOT} L_{FIR} for higher luminosities. We also calculate the SFR density and compare it to other measurements.Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http:/www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200

UV emission and Star Formation in Stephan's Quintet

we present the first GALEX UV images of the well known interacting group of galaxies, Stephan's Quintet (SQ). We detect widespread UV emission throughout the group. However, there is no consistent coincidence between UV structure and emission in the optical, H\alpha, or HI. Excluding the foreground galaxy NGC7320 (Sd), most of the UV emission is found in regions associated with the two spiral members of the group, NGC7319 and NGC7318b, and the intragroup medium starburst SQ-A. The extinction corrected UV data are analyzed to investigate the overall star formation activity in SQ. It is found that the total star formation rate (SFR) of SQ is 6.69+-0.65 M_\sun/yr. Among this, 1.34+-0.16 M_sun/yr is due to SQ-A. This is in excellent agreement with that derived from extinction corrected H\alpha luminosity of SQ-A. The SFR in regions related to NGC 7319 is 1.98+-0.58 M_\sun/yr, most of which(68%) is contributed by the disk. The contribution from the 'young tail' is only 15%. In the UV, the 'young tail' is more extended (~100 kpc) and shows a loop-like structure, including the optical tail, the extragalactic HII regions recently discovered in H\alpha, and other UV emission regions discovered for the first time. The UV and optical colors of the 'old tail' are consistent with a single stellar population of age t ~10^{8.5+-0.4} yrs. The UV emission associated with NGC 7318b is found in a very large (~80 kpc) disk, with a net SFR of 3.37+-0.25 M_sun/yr. Several large UV emission regions are 30 -- 40 kpc away from the nucleus of NGC7318b. Although both NGC7319 and NGC7318b show peculiar UV morphology, their SFR is consistent with that of normal Sbc galaxies, indicating that the strength of star formation activity is not enhenced by interactions.Comment: This paper will be published as part of the Galaxy Evolution Explorer(GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http:/www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200

Recent star formation in nearby galaxies from GALEX imaging:M101 and M51

The GALEX (Galaxy Evolution Explorer) Nearby Galaxies Survey is providing deep far-UV and near-UV imaging for a representative sample of galaxies in the local universe. We present early results for M51 and M101, from GALEX UV imaging and SDSS optical data in five bands. The multi-band photometry of compact stellar complexes in M101 is compared to population synthesis models, to derive ages, reddening, reddening-corrected luminosities and current/initial masses. The GALEX UV photometry provides a complete census of young compact complexes on a approximately 160pc scale. A galactocentric gradient of the far-UV - near-UV color indicates younger stellar populations towards the outer parts of the galaxy disks, the effect being more pronounced in M101 than in M51.Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issue. Full paper available from http://dolomiti.pha.jhu.edu . Links to full set of papers will be available at http://www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200

UV and FIR selected star-forming galaxies at z=0: differences and overlaps

We study two samples of local galaxies, one is UV (GALEX) selected and the other FIR (IRAS) selected, to address the question whether UV and FIR surveys see the two sides ('bright' and 'dark') of the star formation of the same population of galaxies or two different populations of star forming galaxies. No significant difference between the L$_{tot}$ ($=L_{60}+L_{FUV}$) luminosity functions of the UV and FIR samples is found. Also, after the correction for the `Malmquist bias' (bias for flux limited samples), the FIR-to-UV ratio v.s. L$_{tot}$ relations of the two samples are consistent with each other. In the range of 9 \la \log(L_{tot}/L_\sun) \la 12, both can be approximated by a simple linear relation of \log (L_{60}/L_{FUV})=\log(L_{tot}/L_\sun)-9.66. These are consistent with the hypothesis that the two samples represent the same population of star forming galaxies, and their well documented differences in L$_{tot}$ and in FIR-to-UV ratio are due only to the selection effect. A comparison between the UV luminosity functions shows marginal evidence for a population of faint UV galaxies missing in the FIR selected sample. The contribution from these 'FIR-quiet' galaxies to the overall UV population is insignificant, given that the K-band luminosity functions (i.e. the stellar mass functions) of the two samples do not show any significant difference.Comment: 21 pages, 7 figures. Accepted by Ap

GALEX Ultraviolet Photometry of Globular Clusters in M31

We present ultraviolet photometry for globular clusters (GCs) in M31 from 15 square deg of imaging using the Galaxy Evolution Explorer (GALEX). We detect 200 and 94 GCs with certainty in the near-ultraviolet (NUV; 1750 - 2750 Angstroms) and far-ultraviolet (FUV; 1350 - 1750 Angstroms) bandpasses, respectively. Our rate of detection is about 50% in the NUV and 23% in the FUV, to an approximate limiting V magnitude of 19. Out of six clusters with [Fe/H]>-1 seen in the NUV, none is detected in the FUV bandpass. Furthermore, we find no candidate metal-rich clusters with significant FUV flux, because of the contribution of blue horizontal-branch (HB) stars, such as NGC 6388 and NGC 6441, which are metal-rich Galactic GCs with hot HB stars. We show that our GALEX photometry follows the general color trends established in previous UV studies of GCs in M31 and the Galaxy. Comparing our data with Galactic GCs in the UV and with population synthesis models, we suggest that the age range of M31 and Galactic halo GCs are similar.Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http://www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200

The On-Orbit Performance of the Galaxy Evolution Explorer

We report the first year on-orbit performance results for the Galaxy Evolution Explorer (GALEX), a NASA Small Explorer that is performing a survey of the sky in two ultraviolet bands. The instrument comprises a 50 cm diameter modified Ritchey-Chretien telescope with a 1.25 degree field of view, selectable imaging and objective grism spectroscopic modes, and an innovative optical system with a thin-film multilayer dichroic beam splitter that enables simultaneous imaging by a pair of photon counting, microchannel plate, delay line readout detectors. Initial measurements demonstrate that GALEX is performing well, meeting its requirements for resolution, efficiency, astrometry, bandpass definition and survey sensitivity.Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issu

Number Counts of GALEX Sources in FUV (1530A) and NUV (2310A) Bands

Number Counts of galaxies in two GALEX bands (FUV: 1530A and NUV: 2310A, both in AB magnitudes) are reported. They provide for the first time in the literature homogeneously calibrated number counts of UV galaxies covering continuously a very wide range of UV magnitude (14 -- 23.8). Both the FUV and NUV counts are inconsistent with a non-evolution model, while they are in good agreement with evolution models (essentially luminosity evolution) derived from the high-z UV luminosity functions of Arnouts et al. (2004). It is found that the contribution from galaxies detected by GALEX to the UV background is 0.68+-0.10 nW m-2 sr-1 at 1530A and 0.99+-0.15 nW m-2 sr-1 at 2310A. These are 66+-9% and 44+-6% of the total contributions of galaxies to the the UV background at 1530A, respectively, as estimated using the evolution models. ...Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http:/www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200

The UV Galaxy Luminosity Function in the Local Universe from GALEX Data

We present the results of a determination of the galaxy luminosity function at ultraviolet wavelengths at redshifts of $z=0.0-0.1$ from GALEX data. We determined the luminosity function in the GALEX FUV and NUV bands from a sample of galaxies with UV magnitudes between 17 and 20 that are drawn from a total of 56.73 deg^2 of GALEX fields overlapping the b_j-selected 2dF Galaxy Redshift Survey. The resulting luminosity functions are fainter than previous UV estimates and result in total UV luminosity densities of 10^(25.55+/-0.12) ergs s^-1 Hz^-1 Mpc^-3 and 10^(25.72+/-0.12) ergs s^-1 Hz^-1 Mpc^-3 at 1530 Ang. and 2310 Ang., respectively. This corresponds to a local star formation rate density in agreement with previous estimates made with H-alpha-selected data for reasonable assumptions about the UV extinction.Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http://www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200