493 research outputs found

    Self Perceptions of Clinical Performance of Accelerated First Degree and Accelerated Second-Degree Graduates

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    Currently in the United States, motivated by nursing shortages, numerous ways have been created to recruit nurses in nursing schools. Accelerated nursing programs are increasing rapidly. Colleges and Schools of Nursing around the nation are accepting students seeking their first degree, as well as those with a second degree. This study compared perceptions of clinical performance of accelerated first-degree and accelerated second-degree bachelor of nursing graduates. The intention was to identify whether, after graduation, the two groups held different self-perceptions of performance in the clinical environment. This was to determine if one group has better self-perception of performance than the other to explore how these differences can impact accelerated nursing programs and clinical performance after graduation. The results showed no significant differences in the perception of performance between the two groups; concluding degree status has little or no impact on perception of clinical practice and prediction of practice success from an accelerated program

    EVALUATION OF ANTI-ULCER ACTIVITY OF THE ETHANOLIC EXTRACT OF PHYLLANTHUS URINARIA IN EXPERIMENTAL ANIMALS

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    Objective: The objective of this study is to investigate the antiulcer activity of the ethanolic extract of Phyllanthus urinaria (EEPU). Methods: In vivo anti-ulcer activity of EEPU was evaluated in the present study at 500 mg/kg body weight by pyloric ligation, ethanol-induced ulcer, aspirin-induced ulcer, and cold restraint-induced ulcer model. The anti-ulcer activity was assessed by determining and comparing the gastric volume, pH, free and total acidity, ulcer number and its inhibition, and ulcer severity.Result: EEPU at 500 mg/kg body weight dose showed significant antiulcer activity by decreasing ulcer index, gastric volume, pH, and free and total acidity. Gastroprotective effect of EEPU was substantiated by histopathological studies of the stomach in ulcer and treated groups.Conclusion: It can be concluded from the results that EEPU has potential antiulcer activity

    Synthesis and Properties of N-Bromosuccinimide Derivatives of Ammonium Dialkyl/Alkylene Dithiophosphates

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    Reaction of N-bromosuccinimide with ammonium salt of alkylene (dialkyl) dithiophosphates, [OGOPS(2)NH(4); G=−CMe(2)CMe(2)−CH(2)CMe(2)CH(2)−, CMe(2)CH(2)CHMe(2)−, CH(2)CH(2)CHMe(2)−; (RO)(2)PS(2)NH(4); R=C(2)H(5), n−C(3)H(7), i−C(3)H(7)], in 1 : 1 molor ratio in refluxing benzene solution yields red/brown-colored sticky liquids. These newly synthesized complexes have been characterised by physicochemical and spectroscopic techniques (MW, IR, NMR [(1)H and (31)P]). The computational semiempirical calculations (MOPAC6P/c) have also been studied for these complexes. On the basis of the above studies, the formation of P−S−N chemical linkage has been established

    In Vitro Study on total Phenols, Flavonoids Content and DPPH Activity of Withania Species

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    The escalating interest in appraisal of antioxidant power of herbal plant as medicine, the current study was carried out to explore the antioxidant potential of aqueous extracts of Withania somnifera root and Withania coagulan fruit in-vitro. Antioxidant activity; total phenol,total flavonoids and DPPH free radical scavenging assay of Withania somnifera root and Withania coagulans fruit aqueous extracts were determined by using reference standards gallic acid, quercetin and ascorbic acid, respectively. The highest total phenols content (mgGAE/g) and total flavonoids content (mgQE/g) was found to be 33.1±0.82 and 1.86±0.01 respectively in aqueous somnifera root extracts as compared to coagulans fruit extract . The DPPH radical scavenging activity of the both extracts was increased with the increasing concentration and was observed high in aqueous extract insomniferaroot (IC50= 54) than coagulans fruit (69μg/ml) aqueous extract.Thus,Withania somnifera root has potent antioxidant activity and may serve as a good pharmacotherapeutic agent which could be explored to provide affordable medicines to masses

    Toxicity Assessment of Nickel Nitrate and Effect on Total Leucocyte Count in Albino Rat

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    Heavy metals contribute a variety of adverse health effects. There are over 20 different heavy metal toxins that can impact health effects and each toxin produces different behavioural and physiological misconduct in an exposed individual. Heavy metals have bioimportance as trace element but the biotoxic effects of many of them in human biochemistry are of great concern. Hence, there is a need for understanding of the conditions such as concentration and oxidation states which make them harmful and how biotoxicity occurs. Nickel nitrate affects body physiology following its absorption through food, water and air. Predetermined doses of nickel nitrate (Ni(NO3)2] in acute (1d) and subacute (7, 14, 21, 28ds) treatments revealed significant increase in total leucocyte count (TLC). The results indicate extent of toxicity and enhancement in total leucocyte count under toxic stress of nickel nitrate in albino rat

    Toxicological Profile of Aluminium Sulphate and Effect on Protein Profile in Albino Rat

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    World is full of xenobiotic substances such as heavy metal, pesticide and other pollutic agents. Heavy metal is a metallic element of relatively high density greater than 4gm/cm3 or 5 times more greater than water and is toxic even at low concentration. Heavy metals occur as a natural constituent of earth crust, can be emitted into environment by both natural and anthropogenic causes. Major cause of emission is the mining operations. Predetermined doses of aluminium sulphate in acute (1d) and subacute (7, 14, 21, 28ds) treatments revealed significant increase in albumin and globulin. The results are encouraging and highlight the toxic profile of aluminum sulphate and its effect on protein profile in albino rat

    Controlling progression of bacterial biofilm by herbal eye care formulation

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    Pseudomonas aeruginosa and Staphylococcus aureus causing common eye-infection ‘keratitis’ develop resistance to antibiotics by forming biofilm. Present study evaluates anti-biofilm properties of three commercially available eye care herbal formulations against P. aeruginosa and S. aureus. Eye drop formulations were tested for total phenolic content and antimicrobial activity. Biofilm growth over glass in the presence of herbal formulation was examined under fluorescence microscope. The herbal formulations rich in phenolics, tested at 10% (v/v) concentration showed growth inhibitory effect on planktonic cells. During biofilm mode of growth, 10% of herbal formulation caused considerable decline in growth of biofilm, although did not inhibit it completely. The response to different herbal formulations varied markedly among the different bacterial strains tested. Herbal components can significantly affect the surface topology of biofilms, thereby restricting the attachment of the cell to the substratum

    Making a Place for the Next Generation of Geoscientists

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    Early-career scientists from the AGU Mentoring Network discuss how the global pandemic has exacerbated long-standing issues with the availability of positions in and the diversity of the geosciences.</jats:p
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