Aprendizaje-servicio y Trabajo Social

Es una propuesta metodológica aplicada a los estudios de Trabajo Social. Su objetivo es incorporar el método aprendizaje-servicio a la docencia presencial para incrementar el interés y la satisfacción de la comunidad científica y la sociedad civil

From student to social worker: A teaching project for self-knowledge and the formation of professional identity in the Degree of Social Work at the Complutense University of Madrid.

El objetivo del proyecto es que el/la estudiante incorpore la mirada sobre una/o misma/o (el autoconocimiento) como herramienta para su desarrollo profesional y su capacidad de modularse en los contextos complejos de su futura intervención social.Depto. de Trabajo Social y Servicios SocialesFac. de Trabajo SocialFALSEsubmitte

Quorum sensing network in clinical strains of A. baumannii : AidA is a new quorum quenching enzyme

Acinetobacter baumannii is an important pathogen that causes nosocomial infections generally associated with high mortality and morbidity in Intensive Care Units (ICUs). Currently, little is known about the Quorum Sensing (QS)/Quorum Quenching (QQ) systems of this pathogen. We analyzed these mechanisms in seven clinical isolates of A. baumannii. Microarray analysis of one of these clinical isolates, Ab1 (A. baumannii ST-2-clon-2010), previously cultured in the presence of 3-oxo-C12-HSL (a QS signalling molecule) revealed a putative QQ enzyme (α/β hydrolase gene, AidA). This QQ enzyme was present in all nonmotile clinical isolates (67% of which were isolated from the respiratory tract) cultured in nutrient depleted LB medium. Interestingly, this gene was not located in the genome of the only motile clinical strain growing in this medium (A. baumannii strain Ab421-GEIH-2010 [Ab7], isolated from a blood sample). The AidA protein expressed in E. coli showed QQ activity. Finally, we observed downregulation of the AidA protein (QQ system attenuation) in the presence of HO (ROS stress). In conclusion, most of the A. baumannii clinical strains were not surface motile (84%) and were of respiratory origin (67%). Only the pilT gene was involved in surface motility and related to the QS system. Finally, a new QQ enzyme (α/β hydrolase gene, AidA protein) was detected in these strains