142 research outputs found

    Bloch Oscillation under a Bichromatic Laser: Quasi-Miniband Formation, Collapse, and Dynamical Delocalization and Localization

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    A novel DC and AC driving configuration is proposed for semiconductor superlattices, in which the THz AC driving is provided by an intense bichromatic cw laser. The two components of the laser, usually in the visible light range, are near but not exactly resonant with interband Wannier-Stark transitions, and their frequency difference equals the Wannier-Stark ladder spacing. Multi-photon processes with the intermediate states in the conduction (valence) band cause dynamical delocalization and localization of valence (conduction) electrons, and the corresponding formation and collapse of the quasi-minibands.Comment: 4 pages, 3 figure

    Determinación de los parámetros de productividad en los procesos de carenamiento en un varadero mediano

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    Productivity parameters were determined in maintenance works of 16 ships in the slipways of ASTINAVE, a medium-size shipyard at Guayaquil, Ecuador, in the period between April 2008 and January 2009. Typical processes applied during ship maintenance, its units for evaluation and a classification chart are presented. With the registered time (Man-Hour, M-H), mean values, standard deviations and variation coefficients were calculated for each process. Mean value results for each work were: Plating replacement: 0.220 M-H/kg, Hull cleaning: 0.435 M-H/m2-machine, Painting: 0.027 M-H/m2-machine, Cathodic protection: 0.116 M-H/Kg, Thickness measurement: 0.030 M-H/test, Propulsion system: 130.92 M-H/line, Steering system: 54.89 M-H/line, Ship docking/undocking: 43.97 M-H/maneuver, Bottom Valves: 15.83 M-H/#valve, and, Fuel tank cleaning: 0.0093 M-H/gal.Se determinaron Parámetros de Productividad en los trabajos de mantenimiento de 16 embarcaciones en el varadero de ASTINAVE, en Guayaquil, Ecuador, en el periodo Abril 08 hasta Enero 2009. Se describen, definen las unidades para su evaluación y se clasifican los procesos típicos que se desarrollan para el mantenimiento de buques. Con los tiempos (hombres-hora) registrados se calcularon los valores medios, desviaciones estándar y Coeficiente de Variación de los parámetros de cada proceso. Los valores medios resultantes son: Cambio de planchaje 0.220 H-H/kg, Limpieza del Casco 0.435 H-H/m2-máq, Pintado 0.027 H-H/m2-máq, Protección catódica 0.116 H-H/Kg, Medición de espesores 0.030 H-H/prueba, Sistema de Propulsión 130.92 H-H/línea, Sistema de Gobierno 54.89 H-H/línea, Varada/Desvarada 43.97 H-H/maniobra, Válvulas de Fondo 15.83 H-H/#válv, y, Tanques de combustible 0.0093 H-H/gal

    Critical wave-packet dynamics in the power-law bond disordered Anderson Model

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    We investigate the wave-packet dynamics of the power-law bond disordered one-dimensional Anderson model with hopping amplitudes decreasing as HnmnmαH_{nm}\propto |n-m|^{-\alpha}. We consider the critical case (α=1\alpha=1). Using an exact diagonalization scheme on finite chains, we compute the participation moments of all stationary energy eigenstates as well as the spreading of an initially localized wave-packet. The eigenstates multifractality is characterized by the set of fractal dimensions of the participation moments. The wave-packet shows a diffusive-like spread developing a power-law tail and achieves a stationary non-uniform profile after reflecting at the chain boundaries. As a consequence, the time-dependent participation moments exhibit two distinct scaling regimes. We formulate a finite-size scaling hypothesis for the participation moments relating their scaling exponents to the ones governing the return probability and wave-function power-law decays

    Time evolution of the Partridge-Barton Model

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    The time evolution of the Partridge-Barton model in the presence of the pleiotropic constraint and deleterious somatic mutations is exactly solved for arbitrary fecundity in the context of a matricial formalism. Analytical expressions for the time dependence of the mean survival probabilities are derived. Using the fact that the asymptotic behavior for large time tt is controlled by the largest matrix eigenvalue, we obtain the steady state values for the mean survival probabilities and the Malthusian growth exponent. The mean age of the population exhibits a t1t^{-1} power law decayment. Some Monte Carlo simulations were also performed and they corroborated our theoretical results.Comment: 10 pages, Latex, 1 postscript figure, published in Phys. Rev. E 61, 5664 (2000

    Effect of nonlinearity on the dynamics of a particle in dc field-induced systems

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    Dynamics of a particle in a perfect chain with one nonlinear impurity and in a perfect nonlinear chain under the action of dc field is studied numerically. The nonlinearity appears due to the coupling of the electronic motion to optical oscillators which are treated in adiabatic approximation. We study for both the low and high values of field strength. Three different range of nonlinearity is obtained where the dynamics is different. In low and intermediate range of nonlinearity, it reduces the localization. In fact in the intermediate range subdiffusive behavior in the perfect nonlinear chain is obtained for a long time. In all the cases a critical value of nonlinear strength exists where self-trapping transition takes place. This critical value depends on the system and the field strength. Beyond the self-trapping transition nonlinearity enhances the localization.Comment: 9 pages, Revtex, 6 ps figures include

    Exact Solution of an Evolutionary Model without Ageing

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    We introduce an age-structured asexual population model containing all the relevant features of evolutionary ageing theories. Beneficial as well as deleterious mutations, heredity and arbitrary fecundity are present and managed by natural selection. An exact solution without ageing is found. We show that fertility is associated with generalized forms of the Fibonacci sequence, while mutations and natural selection are merged into an integral equation which is solved by Fourier series. Average survival probabilities and Malthusian growth exponents are calculated indicating that the system may exhibit mutational meltdown. The relevance of the model in the context of fissile reproduction groups as many protozoa and coelenterates is discussed.Comment: LaTeX file, 15 pages, 2 ps figures, to appear in Phys. Rev.

    Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity

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    In the last years, the development of new drugs in oncology has evolved notably. In particular, drug development has shifted from empirical screening of active cytotoxic compounds to molecularly targeted drugs blocking specific biologic pathways that drive cancer progression and metastasis. Using a rational design approach, our group has developed 1A-116 as a promising Rac1 inhibitor, with antitumoral and antimetastatic effects in several types of cancer. Rac1 is over activated in a wide range of tumor types and and it is one of the most studied proteins of the Rho GTPase family. Its role in actin cytoskeleton reorganization has effects on endocytosis, vesicular trafficking, cell cycle progression and cellular migration. In this context, the regulatory activity of Rac1 affects several key processes in the course of the cancer including invasion and metastasis. The purpose of this preclinical study was to focus on the mode of action of 1A-116, conducting an interdisciplinary approach with in silico bioinformatics tools and in vitro assays. Here, we demonstrate that the tryptophan 56 residue is necessary for the inhibitory effects of 1A-116 since this compound interferes with protein-protein interactions (PPI) of Rac1GTPase involving several GEF activators. 1A116 is also able to inhibit the oncogenic Rac1P29S mutant protein, one of the oncogenic drivers found in sun-exposed melanoma. It also inhibits numerous Rac1-regulated cellular processes such as membrane ruffling and lamellipodia formation. These results deepen our knowledge of 1A-116 inhibition of Rac1 and its biological impact on cancer progression. They also represent a good example of how in silico analyses represent a valuable approach for drug development.Fil: González, Nazareno. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Oncología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Cardama, Georgina Alexandra. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Oncología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chinestrad, Patricio Manuel. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Farmacología Molecular; ArgentinaFil: Robles Valero, Javier. Universidad de Salamanca; España. Consejo Superior de Investigaciones Científicas; EspañaFil: Rodríguez Fdez, Sonia. Universidad de Salamanca; España. Consejo Superior de Investigaciones Científicas; EspañaFil: Lorenzo Martín, L. Francisco. Universidad de Salamanca; España. Consejo Superior de Investigaciones Científicas; EspañaFil: Bustelo, Xosé R.. Universidad de Salamanca; España. Consejo Superior de Investigaciones Científicas; EspañaFil: Lorenzano Menna, Pablo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Farmacología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gomez, Daniel Eduardo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Oncología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

    Produção de batata no Rio Grande do Sul.

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    The three-dimensional Anderson model of localization with binary random potential

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    We study the three-dimensional two-band Anderson model of localization and compare our results to experimental results for amorphous metallic alloys (AMA). Using the transfer-matrix method, we identify and characterize the metal-insulator transitions as functions of Fermi level position, band broadening due to disorder and concentration of alloy composition. The appropriate phase diagrams of regions of extended and localized electronic states are studied and qualitative agreement with AMA such as Ti-Ni and Ti-Cu metallic glasses is found. We estimate the critical exponents nu_W, nu_E and nu_x when either disorder W, energy E or concentration x is varied, respectively. All our results are compatible with the universal value nu ~ 1.6 obtained in the single-band Anderson model.Comment: 9 RevTeX4 pages with 11 .eps figures included, submitted to PR
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