26 research outputs found
Two-loop Renormalization Factors of Dimension-six Proton Decay Operators in the Supersymmetric Standard Models
The renormalization factors of the dimension-six effective operators for
proton decay are evaluated at two-loop level in the supersymmetric grand
unified theories. For this purpose, we use the previous results in which the
quantum corrections to the effective Kahler potential are evaluated at
two-loop level. Numerical values for the factors are presented in the case of
the minimal supersymmetric SU(5) grand unified model. We also derive a simple
formula for the one-loop renormalization factors for any higher-dimensional
operators in the Kahler potential, assuming that they are induced by the gauge
interactions.Comment: 11 pages. Version accepted for publication in Phys. Lett.
Methicillin-resistant Staphylococcus aureus carriage among veterinary staff and dogs in private veterinary clinics in Hokkaido, Japan
Epidemiological Analysis of Methicillin-Resistant Staphylococcus aureus Carriage among Veterinary Staff of Companion Animals in Japan
Veterinary staff carrying methicillin-resistant Staphylococcus aureus(MRSA) can be a source of MRSA infection in animals. To identify risk factors of MRSA carriage among veterinary staff, MRSA carriage and epidemiological information (sex, career, contact with MRSA-identified animal patients and others) were analyzed from 96 veterinarians and 70 veterinary technicians working at 71 private veterinary clinics in Japan. Univariate analysis determined sex (percentage of MRSA carriage, male (29.2%) vs. female (10%); P=0.002) and career (veterinarians (22.9%) vs. veterinary technicians (10%); P=0.030) as risk factors. Multivariable analysis revealed that sex was independently associated with MRSA carriage (adjusted odds ratio, 3.717; 95% confidence interval, 1.555-8.889; P=0.003). Therefore, male veterinary staff had a higher risk of MRSA carriage than female staff
Continuous Catalytic Oxidation of Glycerol to Carboxylic Acids Using Nanosized Gold/Alumina Catalysts and a Liquid-Phase Flow Reactor
Here,
we report the
development of catalysts comprising highly dispersed Au on an alumina
(Al2O3) support for the oxidation of glycerol
to high-value carboxylic acids in a liquid-phase flow reactor. The
catalysts were prepared by means of a depositionāprecipitation
method. To ensure that the catalysts could be used for long-term catalytic
conversions in a liquid-phase flow reactor, we chose an alumina support
with high temperature stability and a particle size (50ā200
Ī¼m) large enough to prevent leakage of the catalyst from the
reactor. One of the five catalysts had a high catalytic activity for
the conversion of glycerol to the high-value carboxylic acids, glyceric
acid and tartronic acid (conversion of glycerol >70%), and the
catalyst retained its catalytic activity over long-term use (up to
1770 min). Pretreatment of the catalyst with fructose, a mild reductant,
increased the activity of the catalyst. Scanning transmission electron
microscopy revealed three Au species highly dispersed on the surface
of the alumina supportīøAu nanoparticles (mode = 7.5ā10
nm), Au clusters (1ā2 nm), and atomic Au
Epidemiological Analysis of Methicillin-Resistant Staphylococcus aureus Carriage among Veterinary Staff of Companion Animals in Japan
Methicillin-resistant Staphylococcus aureus carriage among veterinary staff and dogs in private veterinary clinics in Hokkaido, Japan
Occurrence and molecular characteristics of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius in an academic veterinary hospital
Recently, methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus pseudintermedius (MRSP) have been increasingly isolated from veterinarians and companion animals. With a view to preventing the spread of MRSA and MRSP, we evaluated the occurrence and molecular characteristics of each in a veterinary college. MRSA and MRSP were isolated from nasal samples from veterinarians, staff members, and veterinary students affiliated with a veterinary hospital. Using stepwise logistic regression, we identified two factors associated with MRSA carriage: (i) contact with an identified animal MRSA case (odds ratio [OR], 6.9; 95% confidence interval [95% CI], 2.2 to 21.6) and (ii) being an employee (OR, 6.2; 95% CI, 2.0 to 19.4). The majority of MRSA isolates obtained from individuals affiliated with the veterinary hospital and dog patients harbored spa type t002 and a type II staphylococcal cassette chromosome mec (SCCmec), similar to the hospital-acquired MRSA isolates in Japan. MRSA isolates harboring spa type t008 and a type IV SCCmec were obtained from one veterinarian on three different sampling occasions and also from dog patients. MRSA carriers can also be a source of MRSA infection in animals. The majority of MRSP isolates (85.2%) carried hybrid SCCmec type II-III, and almost all the remaining MRSP isolates (11.1%) carried SCCmec type V. MRSA and MRSP were also isolated from environmental samples collected from the veterinary hospital (5.1% and 6.4%, respectively). The application of certain disinfection procedures is important for the prevention of nosocomial infection, and MRSA and MRSP infection control strategies should be adopted in veterinary medical practice
Occurrence and molecular characteristics of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius in an academic veterinary hospital
Two-loop renormalization factors of dimension-six proton decay operators in the supersymmetric standard models
RAISING is a high-performance method for identifying random transgene integration sites
Both natural viral infections and therapeutic interventions using viral vectors pose significant risks of malignant transformation. Monitoring for clonal expansion of infected cells is important for detecting cancer. Here we developed a novel method of tracking clonality via the detection of transgene integration sites. RAISING (Rapid Amplification of Integration Sites without Interference by Genomic DNA contamination) is a sensitive, inexpensive alternative to established methods. Its compatibility with Sanger sequencing combined with our CLOVA (Clonality Value) software is critical for those without access to expensive high throughput sequencing. We analyzed samples from 688 individuals infected with the retrovirus HTLV-1, which causes adult T-cell leukemia/lymphoma (ATL) to model our method. We defined a clonality value identifying ATL patients with 100% sensitivity and 94.8% specificity, and our longitudinal analysis also demonstrates the usefulness of ATL risk assessment. Future studies will confirm the broad applicability of our technology, especially in the emerging gene therapy sector.Communications Biology, 5, art. no. 535; 202