Human Following Using Kinect V2

With the emergence of continuously improving imaging and image processing technologies comes the challenge of applying those technologies to create robots that can make navigational decisions based on visual inputs. In this project, a human-following robot is designed and implemented using the Microsoft Kinect v2 system for PC. This system feeds the robot both color and depth information from the environment in front of it, allowing it to navigate obstacles and follow a specific user. The Kinect is used to find the user’s location with respect to the robot, based primarily on what the user is wearing and where the user was last seen. This information is fed to the on-board PC, which uses it to make path-planning decisions and drive the robot’s wheels through communication with a PIC18 microcontroller. This system could be used in a variety of applications, such as shopping carts, airport luggage carriers, or even robotic pets

The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.Comment: Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figure

CUBES : the Cassegrain U-band Efficient Spectrograph

In the era of Extremely Large Telescopes, the current generation of 8-10m facilities are likely to remain competitive at ground-UV wavelengths for the foreseeable future. The Cassegrain U-Band Efficient Spectrograph (CUBES) has been designed to provide high-efficiency (> 40%) observations in the near UV (305-400 nm requirement, 300-420 nm goal) at a spectral resolving power of R >20, 000 (with a lower-resolution, sky-limited mode of R ~7, 000). With the design focusing on maximizing the instrument throughput (ensuring a Signal to Noise Ratio (SNR) ~20 per high-resolution element at 313 nm for U ~18.5 mag objects in 1h of observations), it will offer new possibilities in many fields of astrophysics, providing access to key lines of stellar spectra: a tremendous diversity of iron-peak and heavy elements, lighter elements (in particular Beryllium) and light-element molecules (CO, CN, OH), as well as Balmer lines and the Balmer jump (particularly important for young stellar objects). The UV range is also critical in extragalactic studies: the circumgalactic medium of distant galaxies, the contribution of different types of sources to the cosmic UV background, the measurement of H2 and primordial Deuterium in a regime of relatively transparent intergalactic medium, and follow-up of explosive transients. The CUBES project completed a Phase A conceptual design in June 2021 and has now entered the detailed design and construction phase. First science operations are planned for 2028

Encouraging Signs for Women's Representation in the AVMA House of Delegates in 2014

Data indicate that the percentage of women is increasing in the AVMA’s House of Delegates at a level commensurate with the increase in percentage of women in the DVM classes

Many Mountains, Many Musics, Many Movements

The roundtable focuses broadly on hip hop within Appalachia. Presenters will interact with the audience, but focus briefly on the following:Forrest Yerman will discuss the evolution of spirituals, to blues, to jazz, to rhythm and blues to, funk, to hip hop in a large American context, and apply that discussion to Appalachia. Willard Watson will discuss the publication and distribution of Hip Hop/Rap in the region, differentiating between mainstream artists and mixtape culture within the region and conclude by sharing an online resource for finding Appalachian Hip Hop. Nate May will be speaking to the West Virginia rap scene and his research as a music scholar. Moderator, Jordan Laney, will organize questions and frame the discussion as an exploration of race, aesthetics, and possibilities in the region

Student Governance Digital Business Process

To support evolving expectations for digital business processes and paperwork handling, this project is focused on the creation of a suite of web applications that allow the replacement of a number of paper forms with a more sophisticated system. As an exercise in customer and client management, in collaboration with Craig Behnke (a sophomore senator of the Valparaiso University Student Senate), various customer needs and operational requirements were identified - tiers of privileges and access (someone in UPC shouldn\u27t have access to view the forms of another organization), some forms require approval from Student Senate, while others need to be voted upon. These forms include but are not limited to line item shifts, encumbrance requests, stipend encumbrance requests, and capital expenditure requests. To support digital editions of these forms, a mix of technologies were used. These included HTML and CSS for the front end implementation, and SQL and PHPmyAdmin as back end components. The expected result is a prototype that the Valparaiso University Student Senate can use as the basis for digital record keeping, with a long term aim of decreased reliance on paper, simplified access to student organization information, data security, and less mechanical effort for student governance operations

Student Governance Digital Business Process

To support evolving expectations for digital business processes and paperwork handling, this project is focused on the creation of a suite of web applications that allow the replacement of a number of paper forms with a more sophisticated system. As an exercise in customer and client management, in collaboration with Craig Behnke (a sophomore senator of the Valparaiso University Student Senate), various customer needs and operational requirements were identified - tiers of privileges and access (someone in UPC shouldn\u27t have access to view the forms of another organization), some forms require approval from Student Senate, while others need to be voted upon. These forms include but are not limited to line item shifts, encumbrance requests, stipend encumbrance requests, and capital expenditure requests. To support digital editions of these forms, a mix of technologies were used. These included HTML and CSS for the front end implementation, and SQL and PHPmyAdmin as back end components. The expected result is a prototype that the Valparaiso University Student Senate can use as the basis for digital record keeping, with a long term aim of decreased reliance on paper, simplified access to student organization information, data security, and less mechanical effort for student governance operations

Detrimental effects of physical inactivity on neurogenesis

Patients diagnosed with neurological disorders exhibit a variety of physical and psychiatric symptoms, including muscle atrophy, general immobility, and depression. Patients who participate in physical rehabilitation at times show unexpected clinical improvement, which includes diminished depression and other stress-related behaviors. Regenerative medicine has advanced two major stem cell-based therapies for central nervous system (CNS) disorders, transplantation of exogenous stem cells, and enhancing the endogenous neurogenesis. The latter therapy utilizes a natural method of re-innervating the injured brain, which may mend neurological impairments. In this study, we examine how inactivity-induced atrophy, using the hindlimb suspension model, alters neurogenesis in rats. The hypothesis is that inactivity inhibits neurogenesis by decreasing circulation growth or trophic factors, such as vascular endothelial growth or neurotrophic factors. The restriction modifies neurogenesis and stem cell differentiation in the CNS, the stem cell microenvironment is examined by the trophic and growth factors, including stress-related proteins. Despite growing evidence revealing the benefits of "increased" exercise on neurogenesis, the opposing theory involving "physical inactivity," which simulates pathological states, continues to be neglected. This novel theory will allow us to explore the effects on neurogenesis by an intransigent stem cell microenvironment likely generated by inactivity. 5-bromo-2-deoxyuridine labeling of proliferative cells, biochemical assays of serum, cerebrospinal fluid, and brain levels of trophic factors, growth factors, and stress-related proteins are suggested identifiers of neurogenesis, while evaluation of spontaneous movements will give insight into the psychomotor effects of inactivity. Investigations devised to show how in vivo stimulation, or lack thereof, affects the stem cell microenvironment are necessary to establish treatment methods to boost neurogenesis in bedridden patients

Investigating Protozoal Parasites as Causes of Neurologic Disease in American Black Bears (Ursus americanus) that Contribute to Human-Wildlife Conflict (Abstract)

American black bears (Ursus americanus) can be considered vertebrate pests when they come in conflict with humans and create potential public safety situations that require intervention by local wildlife or animal control departments. Black bears are both omnivorous and highly intelligent, and this combination of characteristics make these animals prone to human habituation and developing an association between humans and easy sources of food. Foraging behaviors can put black bears in undesired or unsafe contact with humans when bears root through garbage on private and public lands, consume crops, prey upon small livestock or pets, cause significant property damage, and wander onto roadways leading to traffic accidents. An increasingly recognized cause of bear-human conflict is neurologic disease, such as that caused by infectious pathogens or toxicity, leading to cognitive or behavioral changes. A unique neurologic disease affecting black bears was first observed in 2014 near Lake Tahoe on the border between California and Nevada. Since then, it has been reported in eight counties in California and two counties in Nevada. Affected bears exhibit a range of neurologic symptoms including tremors, seizures, head tilts, and loss of fear of humans (i.e., “dog-like” behavior). Affected animals are typically young (<3 years old), underweight, and most often present in the spring after early emergence from hibernation. Histopathologic examination of brain tissue from these bears revealed varying degrees of inflammation in the brain (encephalitis), but the cause of this encephalitis was not apparent. Testing for common infectious causes of encephalitis (e.g., rabies, canine distemper virus, canine adenovirus, West Nile virus) and common neurotoxins did not identify a cause of the inflammation. A novel gammaherpesvirus, circovirus, parvovirus, and anellovirus were isolated from subsets of affected bears; however, a direct correlation between viral infection and encephalitis has not been established to date. The goal of this study is to investigate the potential role of protozoal parasites in this encephalitis of unknown origin, as members of this group of pathogens are known causes of encephalitis in humans and animals. Brain tissue from bears with encephalitis (n = 21) and unaffected bears (n = 15) from California and Nevada was screened via PCR targeting two loci commonly used to identify protozoal parasites (ITS1 and 18S). Protozoal parasite DNA was detected in 47.6% of bears with encephalitis (10/21) and 26.7% of unaffected bears (4/15). Parasites detected in bears with encephalitis included Sarcocystis neurona (4/21), S. canis (1/21), S. felis (1/21), an uncharacterized Sarcocystis sp. (1/21), Toxoplasma gondii (1/21), and an uncharacterized Cystoisospora-like species (2/21). Sarcocystis neurona, S. canis, and T. gondii are known to cause encephalitis in humans and animals. Sarcocystis canis is an increasingly recognized pathogen of bears and has been reported to cause inflammation in the brain, liver, and muscle in other geographical regions. The clinical significance of the poorly characterized protozoal species is uncertain. Parasites detected in unaffected bears included T. gondii (1/15), an uncharacterized Sarcocystis species (1/15) and an uncharacterized Cystoisospora-like species (2/15). These results suggest that protozoal parasites, particularly Sarcocystis species, may contribute to encephalitis in juvenile black bears, creating a public safety hazard at the human-wildlife interface

Enhancing endogenous stem cells in the newborn via delayed umbilical cord clamping

There is currently no consensus among clinicians and scientists over the appropriate or optimal timing for umbilical cord clamping. However, many clinical studies have suggested that delayed cord clamping is associated with various neonatal benefits including increased blood volume, reduced need for blood transfusion, increased cerebral oxygenation in pre-term infants, and decreased frequency of iron deficiency anemia in term infants. Human umbilical cord blood contains significant amounts of stem and progenitor cells and is currently used in the treatment of several life-threatening diseases. We propose that delayed cord clamping be encouraged as it enhances blood flow from the placenta to the neonate, which is accompanied by an increase supply of valuable stem and progenitor cells, as well as may improve blood oxygenation and increase blood volume, altogether reducing the infant′s susceptibility to both neonatal and age-related diseases