72 research outputs found
Seasonally flooded stepping stones: emerging diversity of small mammal assemblage in the Amazonia-Cerrado ecotone, central Brazil
Syzygium jambolanum treatment improves survival in lethal sepsis induced in mice
<p>Abstract</p> <p>Background</p> <p>The leaves and the fruits from <it>Syzygium jambolanum </it>DC.(Myrtaceae), a plant known in Brazil as sweet olive or 'jambolão', have been used by native people to treat infectious diseases, diabetes, and stomachache. Since the bactericidal activity of <it>S. jambolanum </it>has been confirmed <it>in vitro</it>, the aim of this work was to evaluate the effect of the prophylactic treatment with <it>S. jambolanum </it>on the <it>in vivo </it>polymicrobial infection induced by cecal ligation and puncture (CLP) in mice.</p> <p>Methods</p> <p>C57Bl/6 mice were treated by the subcutaneous route with a hydroalcoholic extract from fresh leaves of <it>S. jambolanum </it>(HCE). After 6 h, a bacterial infection was induced in the peritoneum using the lethal CLP model. The mice were killed 12 h after the CLP induction to evaluate the cellular influx and local and systemic inflammatory mediators' production. Some animals were maintained alive to evaluate the survival rate.</p> <p>Results</p> <p>The prophylactic HCE treatment increased the mice survival, the neutrophil migration to infectious site, the spreading ability and the hydrogen peroxide release, but decreased the serum TNF and nitrite. Despite the increased migration and activation of peritoneal cells the HCE treatment did not decrease the number of CFU. The HCE treatment induced a significant decrease on the bone marrow cells number but did not alter the cell number of the spleen and lymph node.</p> <p>Conclusion</p> <p>We conclude that the treatment with <it>S. jambolanum </it>has a potent prophylactic anti-septic effect that is not associated to a direct microbicidal effect but it is associated to a recruitment of activated neutrophils to the infectious site and to a diminished systemic inflammatory response.</p
Prevalence of HIV, syphilis, hepatitis B and C among adults with mental illness: a multicenter study in Brazil
Adaptability and stability of organic-grown arabica coffee production using the modified centroid method
A microbiological assessment of the oral hygiene of 24-72-month-old kindergarten children and disinfection of their toothbrushes
Condicionamento osmótico e desempenho de sementes de repolho com diferentes nÃveis de vigor
Micro-leakage at the implant-abutment interface with different tightening torques in vitro
Ecological phytochemistry of Cerrado (Brazilian savanna) plants
The Cerrado (the Brazilian savanna) is one of the vegetation formations of great biodiversity in Brazil and it has experienced strong deforestation and fragmentation. The Cerrado must contain at least 12,000 higher plant species.We discuss the ecological relevance of phytochemical studies carried out on plants from the Cerrado, including examples of phytotoxicity, antifungal, insecticidal and antibacterial activities. The results have been classified according to activity and plant family. The most active compounds have been highlighted and other activities are discussed. A large number of complex biochemical interactions occur in this system. However, only a
small fraction of the species has been studied from the phytochemical viewpoint to identify the metabolites
responsible for these interactions
Antimicrobial capacity of Aloe vera and propolis dentifrice against Streptococcus mutans strains in toothbrushes: an in vitro study
Estimación de la concentración media diaria de material particulado fino en la región del Complejo Industrial y Portuario de Pecém, Ceará, Brasil
A exposição ao material particulado fino (MP2,5) está associada a inúmeros
desfechos à saúde. Desta forma, monitoramento da concentração ambiental
do MP2,5 é importante, especialmente em áreas amplamente industrializadas,
pois abrigam potenciais emissores do MP2,5 e de substâncias com potencial de
aumentar a toxicidade de partÃculas já suspensas. O objetivo desta pesquisa é estimar a concentração diária do MP2,5 em três áreas de influência do
Complexo Industrial e Portuário do Pecém (CIPP), Ceará, Brasil. Foi aplicado
um modelo de regressão não linear para a estimativa do MP2,5, por meio de
dados de profundidade óptica monitorados por satélite. As estimativas foram
realizadas em três áreas de influência (Ai) do CIPP (São Gonçalo do Amarante – Ai I, Paracuru e Paraipaba – Ai II e Caucaia – Ai III, no perÃodo de
2006 a 2017. As médias anuais das concentrações estimadas foram inferiores
ao estabelecido pela legislação nacional em todas as Ai (8µg m-3). Em todas as
Ai, os meses referentes ao perÃodo de seca (setembro a fevereiro) apresentaram
as maiores concentrações e uma predominância de ventos leste para oeste. Os
meses que compreendem o perÃodo de chuva (março a agosto) apresentaram as
menores concentrações e ventos menos definidos. As condições meteorológicas
podem exercer um papel importante nos processos de remoção, dispersão ou
manutenção das concentrações do material particulado na região. Mesmo com
baixas concentrações estimadas, é importante avaliar a constituição das partÃculas finas dessa região, bem como sua possÃvel associação a efeitos adversos Ã
saúde da população local.Exposure to fine particulate matter (PM2.5) is associated with numerous negative health outcomes.
Thus, monitoring the environmental concentration of PM2.5 is important, especially in heavily
industrialized areas, since they harbor potential
emitters of PM2.5 and substances with the potential
to increase the toxicity of already suspended particles. This study aims to estimate daily concentrations of PM2.5 in three areas under the influence of
the Industrial and Port Complex of Pecém (CIPP),
Ceará State, Brazil. A nonlinear regression model
was applied to estimate PM2.5, using satellitemonitored optical depth data. Estimates were
performed in three areas of influence (Ai) of the
CIPP (São Gonçalo do Amarante – AiI, Paracuru
and Paraipaba – AiII, and Caucaia – AiIII), from
2006 to 2017. Estimated mean annual concentrations were lower than established by Brazil’s national legislation in all three Ai (8µg m-³). In all
the Ai, the months of the dry season (September to
February) showed the highest concentrations and
a predominance of east winds, while the months
of the rainy season (March to August) showed
the lowest concentrations and less defined winds
Weather conditions can play an important role in
the removal, dispersal, or maintenance of concentrations of particulate matter in the region. Even
at low estimated concentrations, it is important
to assess the composition of fine participles in this
region and their possible association with adverse
health outcomes in the local population.La exposición al material particulado fino (MP2,5)
está asociada a innumerables problemas de salud.
Por ello, la supervisión de la concentración ambiental del MP2,5 es importante, especialmente en
áreas ampliamente industrializadas, puesto que
albergan potenciales emisores de MP2,5 y de sustancias con potencial de aumentar la toxicidad
de partÃculas ya suspendidas. El objetivo de esta
investigación es estimar la concentración diaria
del MP2,5 en tres áreas de influencia del Complejo Industrial y Portuario de Pecém (CIPP), Ceará,
Brasil. Se aplicó un modelo de regresión no lineal
para la estimación del MP2,5, mediante datos de
profundidad óptica supervisados por satélite. Las
estimaciones fueron realizadas en tres áreas de influencia (Ai) del CIPP (São Gonçalo do Amarante
– Ai I, Paracuru y Paraipaba – Ai II y Caucaia
– Ai III en el perÃodo de 2006 a 2017. Las medias
anuales de las concentraciones estimadas fueron
inferiores a lo establecido por la legislación nacional en todas las Ai (8µg m-³). En todas las Ai, los
meses referentes al perÃodo de sequÃa (de setiembre
a febrero) presentaron las mayores concentraciones y una predominancia de vientos este a oeste,
los meses que comprenden el perÃodo de lluvia
(marzo a agosto) presentaron las menores concentraciones y vientos menos definidos. Las condiciones meteorológicas pueden ejercer un papel importante en los procesos de eliminación, dispersión o
mantenimiento de las concentraciones del material
particulado en la región. Incluso con bajas concentraciones estimadas es importante que se evalúe la
constitución de las partÃculas finas de esta región,
asà como su posible asociación con efectos adversos
para la salud de la población local
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