National Primary Care Day \u2797

No abstract available

The Balanced Budget Act of 1997: Implications for Medicare Reimbursement and Graduate Medical Education

No abstract available

Mobile Cooking Space Cart: Enabling Community with Communal Cooking Spaces

The goal of this thesis is to enable the growth of small communities within apartment building spaces. This was accomplished by designing a common cooking space for apartment buildings. My research proved that a shared cooking space would be beneficial to users for social and security reasons. I am aware that solitude is also important, which is why I designed a space that would not restrict users to a community area. As a result, I designed guidelines for an apartment with both private and public cooking spaces while encouraging users to use the latter through functional differences. These include a furniture design solution that allows users to easily use either cooking space through the use of a mobile cart that provides storage space, table space and seating-providing them access to their common tools, ingredients and dining space regardless of where users decide to cook and eat. This furniture design allows the communal cooking space to function smoothly, enabling residents of apartment buildings to naturally form communities

The Effect of \u3cem\u3eLeucaena leucocephala\u3c/em\u3e on Beef Production and Toxicity in the Chaco Region of Argentina

Hedgerows of the fodder tree legume, Leucaena leucocephala (Lam.) de Wit ssp. glabrata (Rose Zárate) (leucaena), planted with companion grass, provide productive, profitable and sustainable tropical pasture (Shelton and Dalzell 2007). Although leucaena can improve beef production from tropical pastures, poor grower adoption has limited development of leucaena in the Chaco Region of Argentina. This can be partly attributed to: (1) unsuccessful establishment; (2) limited understanding of leucaena management as a forage resource; and (3) concerns about mimosine toxicity. These 3 limitations have been overcome in other regions of the world (e.g. northern Australia and the Chaco Region of Paraguay), but little is known about leucaena management and the protection status of ruminants against mimosine toxicosis in Argentina. The objective of this study was to evaluate the effect of leucaena on beef production and toxicity in the west of the Argentinean Chaco Region. We hypothesise that the introduction of leucaena into grass pastures will significantly increase beef productivity if mimosine toxicosis does not appear

Trial by Fire: The Marshall-Bell Kiln Site in Fredericksburg, Virginia

In 2012 and 2013 community members and local professional archaeologists led by Dovetail Cultural Resource Group worked together to salvage a stoneware waster dump in Fredericksburg, Virginia. More than 17,000 artifacts were recovered, representing two successive potters, Hugh R. Marshall and Francis H. Bell. This article brings together the archaeological and documentary evidence to discuss this short-lived pottery operation of the early 1830s. Considered are the physical attributes of the vessel forms and decorations, and the broader aspects of how this pottery operated within the local community and regional markets

The effect of Leucaena leucocephala on beef production and its toxicity in the Chaco Region of Argentina

Hedgerows of the fodder tree legume, Leucaena leucocephala ssp. glabrata (leucaena), planted with a companion grass, provide productive, profitable and sustainable tropical pasture (Shelton and Dalzell 2007). Although leucaena can improve beef production, poor grower adoption has limited development of leucaena in the Chaco Region of Argentina. Factors contributing to poor adoption include: (1) unsuccessful establishment; (2) limited understanding of leucaena management as a forage resource; and (3) concerns about mimosine toxici-ty. While these 3 limitations have been overcome in other regions of the world (e.g. northern Australia and the Chaco Region of Paraguay), in Argentina little is known about leucaena management and the protection of ruminants against mimosine toxicosis.Instituto de Investigación Animal del Chaco SemiáridoFil: Radrizzani Bonadeo, Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido; Argentina.Fil: Nasca, Jose Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido; Argentina

Human papillomavirus-associated increase in p16INK4A expression in penile lichen sclerosus and squamous cell carcinoma

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2·5, which does not permit commercial exploitationBackground: Human papillomaviruses (HPVs) are sexually transmitted human carcinogens that may play a role in the oncogenesis of penile cancer. Objectives: To investigate the role of HPV infection and expression of the tumour suppressor protein p16INK4A in the pathogenesis of penile cancer. Methods: By means of polymerase chain reaction amplification and reverse hybridization line probe assay to detect HPV infection, and immunohistochemical staining for p16INK4A and Ki67, we analysed 26 penile squamous cell carcinomas (SCCs) and 20 independent penile lichen sclerosus (LS) lesions from 46 patients. Results: HPV DNA was found in 54% of penile SCCs and 33% of penile LS cases in single and multiple infections. High-risk HPV 16 was the predominant HPV type detected. No relationship between Ki67 expression and HPV infection was observed. Strong immunostaining for p16INK4A correlated with HPV 16/18 infection in both penile LS and penile SCC. In our penile SCC series the cancer margins were also associated with penile LS in 13 of 26 lesions, and HPV was detected in seven of the 13 SCC cases associated with LS and in six of the 11 SCC lesions not involving LS. Conclusions: Our study shows a high prevalence of HPV 16 and p16INK4A expression in penile lesions, consistent with an active role for HPV in interfering with the retinoblastoma pathway. High-risk HPV infection could be involved in the tumorigenic process in 50% of penile cancers, and the use of prophylactic HPV vaccines has the potential to prevent these cancers.Peer reviewedFinal Published versio