Enantioselective synthesis of bronchodilating agent (R)-Salmeterol^#

1347-1352Synthesis of β2-adrenoreceptor agonist bronchodilator (R)-Salmeterol has been described with good yields. The synthesis commenced from commercially available starting materials, 4-hydroxy benzaldehyde and phenylbutanoic acid. The features of the synthetic strategy are Wittig olefination and Sharpless asymmetric dihydroxylation

Lanthanum chloride mediated-regeneration of carbonyl compounds from oximes in water

2045-2047An efficient method for the cleavage of oximes to their parent aldehydes and ketones is described using lanthanum chloride and sodium dihydrogen phosphate in water

Lanthanum Chloride Mediated-Regeneration of Carbonyl Compounds from Oximes in Water.

2045-2047An efficient method for the cleavage of oximes to their parent aldehydes and ketones is described using lanthanum chloride and sodium dihydrogen phosphate in water

Neutral alumina-K₂CO₃: An eco-friendly system for synthesis of diaryl ethers under microwave irradiation^†

2478-2481Electron deficient halo benzenes undergo smoothly direct condensation with a wide range of phenols under microwave irradiation using neutral alumina as solid support to yield biaryl ethers in excellent yields

Concise and Efficient Synthesis of Cinepazide

<div><p></p><p>An efficient synthesis of cinepazide has been carried out in four steps with an overall yield of 51%. The synthesis was started from a commercially available 3,4,5-tri-methoxy benzaldehyde. All the reactions were very clean and the isolation of products was also very easy.</p> </div

Synthesis of crop protection agent mandipropamid

940-944A simple synthesis of a novel fungicide mandipropamid has been achieved in six steps, with an overall yield of 43%. Synthesis has been carried out from commercially available starting materials, 4-chloroacetophenone and vanillin. The key steps involved in the synthesis are Cannizzaro and Henry reactions, amide bond formation and O-propargylation

Synthesis of glycoprotein inhibitory agents sinuxylamide A-E

1039-1045Synthesis of naturally occurring Sinuxylamides A-E has been accomplished. Synthesis started from commercially available L-tyrosine. The key reactions involved in this synthesis are amide formation, Mitsunobu etherification and ester hydrolysis