C-conformal Metric Transformations on Finslerian Hypersurface

The purpose of the paper is to give some relation between the originalFinslerian hypersurface and other C-conformal Finslerian hypersufaces. In this pa-per we dene three types of hypersufaces, which were called a hyperplane of the 1stkind, hyperplane of the 2nd kind and hyperplane of the 3rd kind under considerationof C-conformal metric transformation.DOI : http://dx.doi.org/10.22342/jims.17.2.2.59-6

Conformal Change of Finsler Special (α, β)- Metric is of Douglas Type

In this present article, we are devoted to study the necessary and sufficient conditions for a Finsler space with a special (α, β)-metric i.e., F = c1α + c2β + β 2 α ; c2 = 0; to be a Douglas space and also to be Berwald space, where α is Riemannian metric and β is differential 1-form. In the second part of this article we are discussing about conformal change of Douglas space with special (α, β)-metric

Lipid profile among controlled and uncontrolled type-2 diabetic patients in a rural tertiary care center: a comparative study

Background: Diabetes mellitus is one of the major health problem and endemic with rapidly increasing prevalence in both developed and developing countries. It has strong association with dyslipidaemias in relation to glycaemic control and duration of the disease. Dyslipidaemias make diabetic patients more susceptible to coronary artery disease (CAD) which is the major cause of increased mortality and morbidity. Objectives were to estimate the blood glucose levels and lipid profiles among diabetics and to compare the lipid profiles among controlled and uncontrolled diabetic subjects.Methods: A cross sectional study was done including 100 diabetic subjects aged between 40 to 60 years of either sex. Patients were classified into 2 groups with 50 subjects in each group as per their glycemic index. Group 1 was controlled diabetic patients (HbA1c≤7.5%) and Group 2 was uncontrolled diabetic patients (HbA1c>7.5%). Venous blood samples were collected from the subjects. The serum was used for analyzing FBS, PPBS, HbA1c and lipid profiles.Results: FBS, PPBS, HbA1c, total cholesterol, triglycerides and LDL were more in females than male patients but the mean values were not significant statistically except FBS and total cholesterol. All the lipid parameters were elevated among uncontrolled diabetic patients compared to controlled diabetic patients which was statistically significant.Conclusions: Present study concluded that the blood glucose levels and lipid parameters were elevated among uncontrolled diabetics compared to controlled diabetics strongly depicting the co-relation between the glycemic levels and lipid abnormalities. Patients should be educated to monitor regularly and control blood glucose and lipid levels

Awareness about diabetes mellitus and DKA among medical students: an observational study

Background: Diabetes Mellitus (DM) is a global epidemic and a leading cause for increased mortality and morbidity. The prevalence of Diabetes is very high so the management of DM and its complication like diabetic ketoacidosis (DKA) is very crucial in today’s world. Medical students being the future pillars of our health care system were included in this study to know their knowledge towards diabetes and its acute complication DKA.Methods: This study was a questionnaire based observational study conducted in Adichunchanagiri Institute of Medical Sciences, B G Nagara. Final year medical students and interns were included in the study.Results: A total of 150 (75 from each group) questionnaires were collected and analysed. Most of the final year students and interns were aware about the classical symptoms of diabetes (73.33% and 84% respectively) and were aware about the endocrine gland related to diabetes (82.6% and 94.6% respectively) however there were differences about the meaning of PPBS among both the groups. Interns (76%) had better knowledge regarding the fluid replacement in the management of DKA in compared to final year students (41.33%). There was statistically significant difference in knowledge between the two groups regarding GDM.Conclusions: This study identifies that both final year students and interns need to improve the practical knowledge towards diagnostic parameters of DM and treatment of DKA. Continous medical education programmes and workshops should be organised to enhance the knowledge towards DM and its complications

A comparative evaluation of analgesic and anti-inflammatory activities of two medicinal plants rubia cordifolia and cassia fistula in wistar albino rats

Background: Pain and inflammation are disabling accompaniments of many medical conditions. So, controlling both pain and inflammation assumes the top priority for the physician. Inflammation is a part of a complex biological response of vascular tissues to harmful stimuli such as pathogens, chemicals or irritants. Therapy of pain and inflammation has always been debatable.Methods: Rats were divided into 8 groups of 6 animals of each. The anti-inflammatory activity was studied with carrageenan induced rat paw edema and cotton pellet induced granuloma models. The analgesic activity was evaluated using Eddy’s hot plate model. The aqueous extract of Rubia cardifolia root and Cassia fistula leaf preparations were compared with Diclofenac in both acute and sub acute inflammatory models and also in pain model.Results: Various test result parameters were statistically analysed at P value <0.5. In Eddy's hot plate model both RC and CF preparations prolonged the response reaction time, while CF preparation showed longer reaction time than that of RC preparation. In carrageenan induced paw edema and cotton pellet induced granuloma models, both RC and CF preparations showed significant decrease in paw edema volume and granuloma dry weight respectively, but less than that of Diclofenac. RC preparation found to have dose dependant in inflammatory models.Conclusions: RC root and CF leaf preparations were compared head to head and they have been found to have significant dose dependant analgesic activity and dose independent acute and sub acute anti inflammatory activities. Though CF leaf preparation appeared to be a good analgesic than RF root preparation, but failed to do so as an anti inflammatory agent in both inflammatory models. But both test preparations were not equivalent to Diclofenac in all three models

Exact Solution of Field Equation with Constant Ricci Curvature in Finslerian Black Hole

This paper aims to investigate the de Sitter Schwarzschild black hole in the framework of Finslerian space-time because Finslerian geometry can explain problems that Einstein's gravity cannot. For this end, we assume the Ricci curvature is constant in the Finsler space and obtain an exact solution for the field equations in the Finsler space-time. This solution is equivalent to the Finslerian Schwarzschild de Sitter-like black hole. A constant Ricci curvature in Finslerian space-time requires, in its two-dimensional space, the Ricci curvature ($\lambda$) to be constant. We find that for $\lambda\neq1$, this solution resembles a black hole surrounded by a cloud of strings. Furthermore, we investigate null and time-like geodesics for $\lambda=1$.Comment: 20 Pages, 4 figure

Ciprofloxacin induced erythema multiforme: a case report

Erythema multiforme (EM) is an acute, self-limited, and sometimes recurring skin condition that is considered to be a type IV hypersensitivity reaction associated with certain infections, medications, and other various triggers like flavorings and preservatives, such as benzoic acid and cinnamon, immunologic disorders, such as transient selective C4 deficiency of infancy, collagen diseases, vasculitides, sarcoidosis, non-Hodgkin lymphoma, leukemia, multiple myeloma, myeloid metaplasia, and polycythemia, physical or mechanical factors, such as tattooing, radiotherapy, cold, and sunlight, foods, including salmon berries and margarine, malignancy, and hormonal. EM may be present within a wide spectrum of severity. EM minor represents a localized eruption of the skin with minimal or no mucosal involvement. According to a consensus definition, Stevens-Johnson syndrome (SJS) was separated from the EM spectrum and added to toxic epidermal necrolysis (TEN). The two spectra are now divided into the following: (1) EM consisting of erythema minor and major and (2) SJS/TEN. Ciprofloxacin is a second generation fluoroquinolone. Fluoroquinolones are rapidly bactericidal in vitro and are considerably potent against Escherichia coli and various species of Salmonella, Shigella, Enterobacter, Campylobacter, and Neisseria. Mainly used in urinary tract infections, prostatitis, sexually transmitted diseases, gastrointestinal and abdominal infections, respiratory tract infections, bone-joint and soft tissue infections. Metronidazole is a nitroimidazole antimicrobial medication used particularly for anaerobic bacteria and protozoa. It is on the World Health Organizations list of essential medicines, a list of the most important medications needed in a basic health system. Here we report the case of a 39-year-old male patient who presented with EM to the dermatology outpatient department, Adichunchanagiri Hospital and Research Centre. The patient gave a history of taking antimicrobials ciprofloxacin and metronidazole for the treatment of a non-healing wound on the right leg which he sustained in a road traffic accident. The review of the literature has revealed very rare associations of metronidazole and pantoprazole with EM, but cases of ciprofloxacin-induced EM have been reported. Hence, the reported adverse drug reaction has been attributed to ciprofloxacin. In this event, casualty assessment using Naranjo’s scale revealed that ciprofloxacin was a probable cause for the adverse drug reaction

Physical viability of traversable Finslerian wormholes with traceless fluid under conformal symmetry

The current study explores the novel potential of traversable wormhole solutions within the framework of Finsler geometry, incorporating conformal symmetry alongside traceless fluid dynamics. Using the Conformal Killing vector approach, we have discussed the wormholes based on traceless fluid within the intriguing framework of Finsler geometry. The field equations and the associated conformal factor are obtained specifically under the condition of conformal motion in Finsler geometry. Furthermore, we have successfully derived and examined the shape function, considering a range of values for the Finslerian parameter $\lambda$. Our investigation extends to fundamental physical characteristics such as proper radial distance, active mass function, and total gravitational energy, aiming to understand their influence on the traversability of the wormhole. The observation of energy condition violations provides evidence for the exotic matter's presence near the throat, reinforcing the assertion of the Finslerian wormhole's traversability.Comment: 17 pages, 8 figure

Ethyl 4-(3-hydroxy­phen­yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate

In the mol­ecular structure of the title compound, C21H25NO4, the dihydro­pyridine ring adopts a flattened boat conformation while the cyclo­hexenone ring is in an envelope conformation. In the crystal structure, mol­ecules are linked into a two-dimensional network parallel to (10) by N—H⋯O and O—H⋯O hydrogen bonds. The network is generated by R 4 4(30) and R 4 4(34) graph-set motifs