7 research outputs found
Five-year experience with tacrolimus rescue for renal allograft rejection
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/1997
- Field of study
ICAR: endoscopic skullâbase surgery
- Author
- Aaron G
- Aaron GP
- Abergel A
- Abouaf L
- Abrishamkar S
- Acioly MA
- Acioly MA
- Acuna RT
- Adams AS
- Adappa ND
- Aferzon M
- Agaimy A
- Agarwal A
- Aggarwal A
- Agrawal D
- Ahmed OH
- Aihara M
- Akagami R
- Alahmadi H
- Albu S
- Albu S
- Albu S
- Alexander A
- Alimohamadi M
- Almefty R
- Almeida JR
- Almeida JR
- Almeida JR
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- Almeida JR
- Almeida JR
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- Alobaid A
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- AlQahtani A
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- Alvarez FL
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- AlâMamgani A
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- Amano K
- Amdur RJ
- Amelot A
- American Academy of Pediatrics Steering Committee on Quality Improvement and Management
- Amichetti M
- Amin SM
- Amit M
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- Anari S
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- Anderson RL
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- Tajudeen BA
- Tam S
- Tamasauskas A
- Tami TA.
- Tan G
- Tan NC
- Tanei T
- Taniguchi M
- Taniguchi M
- Tanzler ED
- Tavanaiepour D
- Tay HN
- Taylor RJ
- Teachey W
- Terranova P
- Thakar A
- Thaker A
- Thawani JP
- Thirumala P
- Thirumala PD
- Thirumala PD
- Thirumala PD
- Thirumala PD
- Thompson CF
- Thompson ED
- Thompson LD
- Thorp BD
- Thotakura AK
- Tien DA
- Tishler RB
- Tomazic PV
- Tomita T
- Tosaka M
- Tosun F
- Trautmann JC
- Trifanescu R
- Tsang RK
- Tsirbas A
- Tu GY
- Tu M
- Turan N
- Turel MK
- Turel MK
- Turner JH
- TurriâZanoni M
- Tyrrell JB
- Tzortzidis F
- Ulfarsson E
- Unsal AA
- Upadhyay S
- Vaezeafshar R
- Valentine R
- Valentine R
- Valentine R
- Varlotto JM
- VazâGuimaraes F
- VazâGuimaraes F
- Veeravagu A
- Vellutini Ede A
- Velthoven V
- Verrees M
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- Vescan AD
- Veyrat M
- Vikram B
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- Virk JS
- Vlantis AC
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- Wadsworth B
- Waldbauer H
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- Wallace SA
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- Walsh TE
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- Wang X
- Wang YY
- Wang YY
- Wanibuchi M
- Wannemuehler TJ
- Webb SM
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- Wei M
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- Weidenbecher M
- Weiland DA
- Weiner HL
- Weiss M
- Weiss MH
- Wen YH
- Wendler O
- Wenig BM
- Wessell A
- Wheless SA
- Wigand ME
- Wilson CB
- Wilson CB.
- Wilson PJ
- Wise SK
- Wise SK
- Wise SK
- Wiseman SM
- Witte O
- Wong EHC
- Wood JW
- Woodworth BA
- Woodworth BA
- Wormald PJ
- Wu JS
- Wu W
- Xie L
- Xie T
- Xie T
- Xiong L
- Xu CC
- Xu F
- Xu R
- Xu Z
- Yan CH
- Yang I
- Yang QT
- Yang T
- Yano S
- Yano S
- Yao WC
- Yasargil MG
- Yasargil MG
- Yasargil MG
- Ye L
- Yildirim AE
- Yilmazlar S
- Yin ZZ
- Yin ZZ
- Yiotakis I
- Yonezawa K
- Yoo F
- Yoshida E
- Yoshizaki T
- You R
- Youssef AS
- Youssef S
- Yunoue S
- YuâWaiâMan P
- Zacharia BE
- Zada G
- Zaidi HA
- Zanation AM
- Zanation AM
- Zanation AM
- Zanation AM
- Zanation AM
- Zhan R
- Zhang C
- Zhang H
- Zhang HK
- Zhang L
- Zhang M
- Zhang Q
- Zhang Q
- Zhang Q
- Zhang Q
- Zhou Q
- Zhou Q
- Zimmer LA
- Zoli M
- Zoli M
- Zou X
- Zrebeet HA
- Zuccaro G.
- Zuniga MG
- Zwagerman NT
- Publication venue
- Publication date
- 01/07/2019
- Field of study
n/
A biomaterials approach to influence stem cell fate in injectable cell-based therapies
- Author
- A Higuchi
- A Mackay-Sim
- AB Faia-Torres
- AJ Engler
- BA Aguado
- BT Estes
- C Frantz
- C Yan
- CD Hoemann
- CE Holy
- CE Murry
- CJ Kearney
- CJ Teng
- D Jiang
- D Kalladka
- D Lu
- DD Dewitt
- DJ Mooney
- E Potier
- EE Golub
- EM Torres
- F Boccafoschi
- F Grinnell
- F Grinnell
- FG Camacho
- FM Watt
- G Altankov
- G Yourek
- GA Di Lullo
- GN Bancroft
- H Salama
- HJ Prins
- HL Holtorf
- I Van Nieuwenhove
- J Shearn
- J Wei
- JB Phillips
- JD Glass
- JH Lee
- K Gelse
- K Moriya
- L Hao
- LT Saldin
- LY Qiao
- M Dominici
- M Gingras
- M Gonen-Wadmany
- M Grellier
- M Mizuno
- M Shayegan
- MH Amer
- MH Amer
- MJ Sawkins
- MP Lutolf
- MR Kreke
- N Huebsch
- PB Malafaya
- PH Rosado-de-Castro
- Q Chen
- R McBeath
- RM Salasznyk
- RN Tharanathan
- S Wu
- SB Seif-Naraghi
- SF Badylak
- SZ Lin
- T Bialopiotrowicz
- T Miyamoto
- T Rossetti
- V Misra
- WL Grayson
- XF Ni
- Y Sun
- Y Xiong
- YJ Li
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2018
- Field of study
Background
Numerous stem cell therapies use injection-based administration to deliver high-density cell preparations. However, cell retention rates as low as 1% have been observed within days of transplantation. This study investigated the effects of varying administration and formulation parameters of injection-based administration on cell dose recovery and differentiation fate choice of human mesenchymal stem cells.
Methods
The impact of ejection rate via clinically relevant Hamilton micro-syringes and biomaterial-assisted delivery was investigated. Cell viability, the percentage of cell dose delivered as viable cells, proliferation capacity as well as differentiation behaviour in bipotential media were assessed. Characterisation of the biomaterial-based cell carriers was also carried out.
Results
A significant improvement of in-vitro dose recovery in cells co-ejected with natural biomaterials was observed, with ejections within 2% (w/v) gelatin resulting in 87.5â±â14% of the cell dose being delivered as viable cells, compared to 32.2â±â19% of the dose ejected in the commonly used saline vehicle at 10 ÎŒl/min. Improvement in cell recovery was not associated with the rheological properties of biomaterials utilised, as suggested by previous studies. The extent of osteogenic differentiation was shown to be substantially altered by choice of ejection rate and cell carrier, despite limited contact time with cells during ejection. Collagen type I and bone-derived extracellular matrix cell carriers yielded significant increases in mineralised matrix deposited at day 21 relative to PBS.
Conclusions
An enhanced understanding of how administration protocols and biomaterials influence cell recovery, differentiation capacity and choice of fate will facilitate the development of improved administration and formulation approaches to achieve higher efficacy in stem cell transplantation
Combining Membrane Potential Imaging with Other Optical Techniques
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- A Bullen
- A Bullen
- A Matiukas
- A Roth
- BA Milojkovic
- BL Sabatini
- BL Sabatini
- BL Sabatini
- BS Sabatini
- E Fluhler
- E Neher
- EO Mann
- F Zhang
- FF Trigo
- J Eilers
- JJ Mancuso
- JP Kao
- JP Wuskell
- JY Wu
- KE Vogt
- KE Vogt
- KL Hyrc
- L Cueni
- L Fierro
- LM Loew
- M Canepari
- M Canepari
- M Canepari
- M Canepari
- M Canepari
- M Djurisic
- M Naraghi
- MZ Kee
- N Jaafari
- O Yizhar
- P Yan
- R Martinez-Zaguilan
- R Schneggenburger
- R Yuste
- RK Gupta
- RN LeĂŁo
- S Antic
- S Tsuda
- S Willadt
- SD Brenowitz
- SG Kremer
- SR Sinha
- SR Sinha
- T Berger
- W-L Zhou
- Publication venue
- HAL CCSD
- Publication date
- 01/01/2015
- Field of study
International audienc
The disappearance of femoral head and neck resulting from extensive bone defect caused by secondary syphilis: a case report and literature review
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- A Mindel
- A Ogungbemi
- A Spyridonidis
- A Zierenberg
- AJ Reginato
- AJ Reginato
- AM Allen
- AM Naraghi
- B Alraddadi
- B Kumar
- C Son
- CA Jacobs
- Chuang Yuan
- D Daskalakis
- D Siegel
- DL Jones
- DR Coblentz
- E Denes
- EWR Hook
- FW Reynolds
- G Kandelaki
- GP Domantay-Apostol
- J Greenall
- J Nakamura
- J Saito
- JD Parker
- JE Olle-Goig
- JG de Carvalho
- JL Meier
- JM Trevillyan
- JP Hauzeur
- K Coyne
- K Eisendle
- K Hansen
- K Mohamed Sarjun Basha
- K Thakore
- K Veerapen
- KA Workowski
- KH Park
- L Elopre
- L Jones
- LR Petersen
- M Brucar
- M Di Monaco
- M Thein
- MS Kuster
- P Gopal
- Peixiong Liang
- R Ehrlich
- RB Roy
- RG Thompson
- RJ Kastner
- RN Shore
- S Middleton
- SE Cohen
- SE Rademacher
- T Fabricius
- Tang Liu
- V Boix
- W Cherniak
- Wanchun Wang
- WR Brain
- Xiao Liang
- Y Yuan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Emerging MRI methods in rheumatoid arthritis
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- A Bashir
- A Bashir
- A Borthakur
- AC Kight
- AI Catrina
- AM Naraghi
- B Ostendorf
- BJ Dardzinski
- BJ Ejbjerg
- C Schirmer
- C van der Leij
- Camilo G. Borrero
- D Perry
- E Fragonas
- EA Haavardsholm
- EC Arner
- EM Lewiecki
- EM Moran
- F McQueen
- F Rannou
- FM McQueen
- FM McQueen
- FM McQueen
- FM McQueen
- H Nagase
- H Sugimoto
- HE Smith
- I Van Breuseghem
- J Tehranzadeh
- JA Buckwalter
- JA NarvĂĄez
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- James M. Mountz
- JJ Steinberg
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- John D. Mountz
- K Andreas
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- M Hashizume
- M Klarlund
- M Ostergaard
- M Ostergaard
- M Ostergaard
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- PC Taylor
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- S Sur
- SB Abramson
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- T Dorner
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- UM Dohn
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- V Agarwal
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
ICAR: endoscopic skullâbase surgery
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- Aaron GP
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- American Academy of Pediatrics Steering Committee on Quality Improvement and Management
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- McLaughlin N
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- Minamida Y
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- Mitchell EH
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- MohammadiâAraghi H
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- NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee
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- O'Connell BP
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- Palani A
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- Patel MR
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- Patel SN
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- Weiland DA
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- Wiseman SM
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- Yunoue S
- YuâWaiâMan P
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- Publication venue
- 'Wiley'
- Publication date
- Field of study