30 research outputs found

    Underlying Event measurements in pp collisions at s=0.9 \sqrt {s} = 0.9 and 7 TeV with the ALICE experiment at the LHC

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    Determinants of food waste: a systematic review of the households behaviour

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    On September 23rd to the 25th of 2022, The University of Gastronomic Sciences of Pollenzo, together with the University of Turin, organised the Symposium “Gastronomy at the crossroad of ecological transition and social justice: Toward the International Society for Gastronomic Sciences and Studies.” The Symposium was devoted to scholarly exchange of knowledge and reflections on the links between gastronomy, ecological transition, and food justice. The main aim of the Symposium was to provide a shared overview of the recent research regarding sustainable gastronomic sciences and studies and to explore the possibility of establishing an International Society of Gastronomic Sciences and Studies. This was considered crucial in the present scenario, as studies concerning the complexity of gastronomy are highly fragmented in different disciplinary fields while the holistic view of “gastronomic systems” is considered crucial for challenging the ongoing conundrums - most notably the ecological transition and unequal distributions of food access and resources

    Climate Change and Natural Resource Scarcity: A Literature Review on Dry Farming

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    The agricultural sector is facing the challenge of climate change, which is increasing difficulties to the activity and the economic sustainability of the primary sector, also affecting farmers’ revenues. There is a growing need to support policy makers’ decisions and help them develop cross-sectional strategies to support farmers. To this aim and to collect useful information for policy makers and stakeholders for the development of efficient strategies for the management of dryland farming, the paper examines how this issue has been analysed in the literature. A mixed method, based on a systematic literature review and a bibliometric analysis of 79 Scopus documents using VOSviewer software, was applied. Major results highlight the need to implement participatory policy interventions so as to include farmers. It was possible to summarise the main adaptive and technical interventions implemented by farmers. The results indicated the importance of the concept of the resilience of territories and the need to analyse agricultural systems by considering their multifunctionality. The innovativeness of this study relies on its relationships with several policy aspects and not only with purely technical and agronomical features, analysing thus the issue from the under-investigated perspective of the global challenge, contributing to filling this literature gap

    Are Potential Tourists Willing to Pay More for Improved Accessibility? Preliminary Evidence from the Gargano National Park

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    Due to the recent COVID-19 pandemic, tourist destinations have been increasingly selected on the basis of health, safety and social distancing criteria. In this framework, protected natural areas represent ideal tourist destinations due to the presence of wide and open spaces, services for tourists and attention to nature. The present paper focused on accessible tourism, a subset of sustainable tourism that is increasingly gaining greater importance within the tourism sector. By applying the Contingent Valuation Method, the study investigated whether potential tourists are effectively willing to pay extra money to be granted more accessible facilities in a natural area. To this end, a logit model was estimated to determine the probability that tourists exhibit a higher WTP for accessible tourism facilities. The analysis was carried out in the Gargano National Park, Southern Italy, an area traditionally characterised by large tourist flows that have increased further during the recent pandemic. The results showed that only a limited percentage of the respondents are willing to pay a higher amount for improved accessibility. These results represent an interesting starting point to outline an adequate strategy for the tourism valorisation of the natural area

    Are Potential Tourists Willing to Pay More for Improved Accessibility? Preliminary Evidence from the Gargano National Park

    No full text
    Due to the recent COVID-19 pandemic, tourist destinations have been increasingly selected on the basis of health, safety and social distancing criteria. In this framework, protected natural areas represent ideal tourist destinations due to the presence of wide and open spaces, services for tourists and attention to nature. The present paper focused on accessible tourism, a subset of sustainable tourism that is increasingly gaining greater importance within the tourism sector. By applying the Contingent Valuation Method, the study investigated whether potential tourists are effectively willing to pay extra money to be granted more accessible facilities in a natural area. To this end, a logit model was estimated to determine the probability that tourists exhibit a higher WTP for accessible tourism facilities. The analysis was carried out in the Gargano National Park, Southern Italy, an area traditionally characterised by large tourist flows that have increased further during the recent pandemic. The results showed that only a limited percentage of the respondents are willing to pay a higher amount for improved accessibility. These results represent an interesting starting point to outline an adequate strategy for the tourism valorisation of the natural area

    Polarized mitochondria as guardians of NK cell fitness

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    International audienceDistinct metabolic demands accompany lymphocyte differentiation into short-lived effector and long-lived memory cells. How bioenergetics processes are structured in innate natural killer (NK) cells remains unclear. We demonstrate that circulating human CD56Dim (NKDim) cells have fused mitochondria and enhanced metabolism compared with CD56Br (NKBr) cells. Upon activation, these 2 subsets showed a dichotomous response, with further mitochondrial potentiation in NKBr cells vs paradoxical mitochondrial fission and depolarization in NKDim cells. The latter effect impaired interferon-Îł production, but rescue was possible by inhibiting mitochondrial fragmentation, implicating mitochondrial polarization as a central regulator of NK cell function. NKDim cells are heterogeneous, and mitochondrial polarization was associated with enhanced survival and function in mature NKDim cells, including memory-like human cytomegalovirus-dependent CD57+NKG2C+ subsets. In contrast, patients with genetic defects in mitochondrial fusion had a deficiency in adaptive NK cells, which had poor survival in culture. These results support mitochondrial polarization as a central regulator of mature NK cell fitness

    Dichotomous metabolic networks govern human ILC2 proliferation and function

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    International audienceGroup 2 innate lymphoid cells (ILC2s) represent innate homologs of type 2 helper T cells (T H 2) that participate in immune defense and tissue homeostasis through production of type 2 cytokines. While T lymphocytes metabolically adapt to microenvironmental changes, knowledge of human ILC2 metabolism is limited, and its key regulators are unknown. Here, we show that circulating ‘naive’ ILC2s have an unexpected metabolic profile with a higher level of oxidative phosphorylation (OXPHOS) than natural killer (NK) cells. Accordingly, ILC2s are severely reduced in individuals with mitochondrial disease (MD) and impaired OXPHOS. Metabolomic and nutrient receptor analysis revealed ILC2 uptake of amino acids to sustain OXPHOS at steady state. Following activation with interleukin-33 (IL-33), ILC2s became highly proliferative, relying on glycolysis and mammalian target of rapamycin (mTOR) to produce IL-13 while continuing to fuel OXPHOS with amino acids to maintain cellular fitness and proliferation. Our results suggest that proliferation and function are metabolically uncoupled in human ILC2s, offering new strategies to target ILC2s in disease settings
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