2,344 research outputs found
Risk Factors for Readmission in Patients with Heart Failure
https://digitalcommons.psjhealth.org/stvincent-bootcamp/1001/thumbnail.jp
Utilization of Palliative Care to Reduce 30 Day Readmission in Heart Failure Patients
https://digitalcommons.psjhealth.org/stvincent-bootcamp/1011/thumbnail.jp
Risk Factors for Readmission in Patients with Heart Failure
https://digitalcommons.psjhealth.org/summit_all/1035/thumbnail.jp
Duration of Posttraumatic Amnesia Predicts Neuropsychological and Global Outcome in Complicated Mild Traumatic Brain Injury.
OBJECTIVES: Examine the effects of posttraumatic amnesia (PTA) duration on neuropsychological and global recovery from 1 to 6 months after complicated mild traumatic brain injury (cmTBI).
PARTICIPANTS: A total of 330 persons with cmTBI defined as Glasgow Coma Scale score of 13 to 15 in emergency department, with well-defined abnormalities on neuroimaging.
METHODS: Enrollment within 24 hours of injury with follow-up at 1, 3, and 6 months.
MEASURES: Glasgow Outcome Scale-Extended, California Verbal Learning Test II, and Controlled Oral Word Association Test. Duration of PTA was retrospectively measured with structured interview at 30 days postinjury.
RESULTS: Despite all having a Glasgow Coma Scale Score of 13 to 15, a quarter of the sample had a PTA duration of greater than 7 days; half had PTA duration of 1 of 7 days. Both cognitive performance and Extended Glasgow Outcome Scale outcomes were strongly associated with time since injury and PTA duration, with those with PTA duration of greater than 1 week showing residual moderate disability at 6-month assessment.
CONCLUSIONS: Findings reinforce importance of careful measurement of duration of PTA to refine outcome prediction and allocation of resources to those with cmTBI. Future research would benefit from standardization in computed tomographic criteria and use of severity indices beyond Glasgow Coma Scale to characterize cmTBI
An integrated approach to rotorcraft human factors research
As the potential of civil and military helicopters has increased, more complex and demanding missions in increasingly hostile environments have been required. Users, designers, and manufacturers have an urgent need for information about human behavior and function to create systems that take advantage of human capabilities, without overloading them. Because there is a large gap between what is known about human behavior and the information needed to predict pilot workload and performance in the complex missions projected for pilots of advanced helicopters, Army and NASA scientists are actively engaged in Human Factors Research at Ames. The research ranges from laboratory experiments to computational modeling, simulation evaluation, and inflight testing. Information obtained in highly controlled but simpler environments generates predictions which can be tested in more realistic situations. These results are used, in turn, to refine theoretical models, provide the focus for subsequent research, and ensure operational relevance, while maintaining predictive advantages. The advantages and disadvantages of each type of research are described along with examples of experimental results
The Influence of a Court Appointed Special Advocate on the Length of Time in Out -Of -Home Care.
The purpose of this study was to determine the influence of participation in a CASA child advocacy program on the length of time in out-of-home placement among children in foster care. Two groups of children, one group having a CASA volunteer, and the other not having a CASA volunteer, were compared on selected characteristics. Also, this study sought to determine if a model existed that explains a significant portion of the variance in the length of time in out-of-home placement among children in foster care. The demographic information analyzed was obtained using recorded information from the computerized files of the local CASA office and information recorded from interviews with assigned caseworkers for children in foster care. The study used data on 289 subjects, CASA group (n = 193) and Non-CASA group (n = 96), which was the entire population of children in foster care during the period of July 1, 1998--June 30, 1999. The results of this study indicated that the subjects were diverse in ages and mostly African-American. The majority was male and neglect was the most prevalent reason for initial placement. Most were placed with their siblings at the time of their initial placement and most were placed initially within 30 miles of their original home. Comparing the CASA and Non-CASA groups revealed that the CASA group was younger and was found to be more likely to have been placed within 30 miles of their original home. Also, the CASA group of children was found to have spent a significantly shorter time in out-of-home care. Using a regression analysis, it was found that a model does exist that explained a significant portion of the variance in the length of time in out-of-home placement among children in the study. This model included 3 factors; whether or not the child had a CASA, age, and whether or not the child was biracial. This study offers considerable support for the position of those that believe that a CASA program is an important aspect of reducing the length of time a child spends in foster care
Gatekeepers of Venture Growth: A Diana Project Report on the Role and Participation of Women in the Venture Capital Industry
Based on 1995 and 2000 data and interviews with women venture capitalists, examines the factors that limit women's level of influence in the industry, women entrepreneurs' connections with venture capitalists, and investment in women-led businesses
Improving Patient Experience by Providing Consistent Education Regarding Medication Side Effects
https://digitalcommons.psjhealth.org/stvincent-bootcamp/1033/thumbnail.jp
Mucosal Immunity Induced by Parenteral Immunization with a Live Attenuated Venezuelan Equine Encephalitis Virus Vaccine Candidate
Induction of a mucosal immune response is generally thought to require introduction of an immunogen directly onto the mucosal surface. It has been observed, however, that live, attenuated mutants of the alphavirus, Venezuelan equine encephalitis virus (VEE), induce protection from virulent challenge at the respiratory mucosa even after parenteral inoculation. In this report, we propose a mechanism by which subcutaneous immunization with a molecularly cloned, attenuated double mutant of VEE is able to stimulate the production of mucosal anti-VEE IgA. Our results showed that the immunizing virus spread to, and replicated within, lymphoid tissues throughout the mouse. Several tissues known to be inductive sites of the mucosal immune system were found to be positive for the presence of VEE RNA by 48 hr postimmunization. Moreover, this mucosal lymphotropism resulted in the production of virus-specific IgA antibody detectable in vaginal secretions of immunized mice
- …