1,579 research outputs found

    Voyager mission support (2)

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    The Deep Space Network report on tracking and data acquisition for Voyager Project is continued. The period of August through October 1980 is covered. The use of beacons for interplanetary navigation, specifically for target related navigation, was shown to be of significant value

    New Approaches to the Use of Twins in Biomedical Research

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    Human geneticists are often accused of being preoccupied with exotic syndromes that are of marginal relevance to the general population. Brilliant success has been achieved during the past two decades in defining the nature and function of the genetic material, the molecular pathology of a large number of metabolic diseases, the phenotype of more than 2,000 Mendelian traits, and more recently the chromosomal location of a rapidly expanding number of human gene pairs. In contrast, relatively little progress has been made in the genetic analysis of quantitative traits such as blood pressure, serum cholesterol, intelligence quotient, skin color, height, birth weight, or glucose tolerance. Traits of this type are not only of interest to society, but may also relate significantly to a variety of common diseases. With almost every continuously distributed quantitative trait, single gene defects have been identified which can profoundly alter the phenotype. For example, the single gene pairs which determine albinism and Tay-Sachs disease can profoundly alter skin color and IQ respectively. However, the causes of less extreme variation can be exceedingly complex, resulting from the cumulative effects of many gene pairs and their interactions with each other and with the environment. Nevertheless, even if the effects of individual gene pairs cannot be identified, the source of the observed variation may often be inferred from an analysis of the phenotypic correlation of relatives of various degree. Twin studies have been widely used in the past to gain insight into the inheritance of quantitative traits, and with the support of a Program Project Grant from the National Institute of Maternal and Child Health, the Department of Human Genetics at the Medical College of Virginia has become a leader in the use of twins for biomedical research

    Community Education: Is It Possible?

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    The community school concept sees the entire community as an educational institution. Likewise living in a community is a full-time educational experience. Community education is the program which brings school and community together

    The Relevance of Genetics to Medicine [Introduction]

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    This issue of the MCV Quarterly focuses on the explosion of knowledge in the field of human genetics. The activities of the new Department of Human Genetics at the Medical College of Virginia encompass the traditional medical school triad of teaching, patient care, and research, and an active graduate program has been developed with curricula leading to masters and doctorate degrees. The program is supported by a recently awarded National Institutes of Health predoctoral training grant as well as State and local funds from the A.D. Williams Foundation

    THE OBJECTIVES AND REQUIREMENTS OF MODEL MANAGEEMENT

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    Model management is a technology evolving by necessity, pushed by the attempts to deal with increasingly complex systems and the perceived inadequacies of past efforts. This rapid evolution of Model Management Systems (MMS) has created different perspectives of the role of the MMS; one arising the user's interaction with a model data bank and the other view from the in the database and decision support systems research community stressing modeling community emphasizing the model development functions. These two perspectives are clarified and reconciled by relating each to the model life cycle, which leads to a more comprehensive statement of MMS requirements

    THE MIXED METHOD OF RANDOM NUMBER GENERATION: A TUTORIAL

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    Several motivations are recognized for user-defined random number generators in preference to built-in generators. The mixed method of random number generation is discussed) and the conditions for achieving full period with a modulus of 2^b are explained. Implementation of mixed random number generators is affected both by the computer and language used. Guidelines are presented for realizing acceptable mixed generators on several machines using the FORTRAN, PL/l and SNOBOL4 languages

    The American Bar Association Joint Task Force on Reversing the School-to-Prison Pipeline Preliminary Report

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    In 2014, the American Bar Association (ABA) Coalition on Racial and Ethnic Justice (COREJ) turned its attention to the continuing failures in the education system where certain groups of students — for example, students of color, with disabilities, or LGBTQ — are disproportionately over- or incorrectly categorized in special education, are disciplined more harshly, including referral to law enforcement for minimal misbehavior, achieve at lower levels, and eventually drop or are pushed out of school, often into juvenile justice facilities and prisons — a pattern now commonly referred to as the School-to-Prison Pipeline. While this problem certainly is not new, it presented a convergence of several laws, policies, and practices where the legal community’s intervention is critical. Joined by the ABA Pipeline Council and Criminal Justice Section, and supported by its sister ABA entities, COREJ sponsored a series of eight Town Halls across the country to investigate the issues surrounding this pipeline. The focus of these Town Halls was to 1) explore the issues as they presented themselves for various groups and various locales; 2) gather testimony on solutions that showed success, with particular focus on interventions where the legal community could be most effective in interrupting and reversing the School-to-Prison Pipeline; and 3) draw attention to the role implicit bias plays in creating and maintaining this pipeline. This report is a result of those convenings

    The Genetic Counseling Program at MCV

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    The Genetic Counseling Clinic at the Medical College of Virginia, established by Drs. Peter Mamunes and R.B. Young in 1973, has been supported since its inception by a clinical service grant from the National Foundation – March of Dimes; it is one of 83 genetic counseling programs in the United States and one of three in Virginia that receive support from the Foundation. The Clinic provides counseling and diagnostic services for a variety of genetic disease and is the focus of clinical teaching and research activities of the Department of Human Genetics. The Clinic is staffed by member of the Departments of Human Genetics, Obstetrics, and Pediatrics, as well as consultants from many other clinical disciplines
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