Implementasi Algoritma K-Nearest Neighbour Untuk Menentukan Nomor Klasifikasi Buku Studi Kasus: Perpustakaan Universitas Katolik Musi Charitas)

Classification of library books is important to allow visitors in search of a book. The classification system in the library of the Catholic University of Charity Musi using guide books dewey decimal classification (DDC). The problem in this research is the difficulty in determining the classification number of new books. By utilizing the methods of Information Retrieval (IR) or retrieval of information, so in this study will build an application program for classification of library books. The method will be used to classify the book library is a method of k-nearest neighbor (k-NN). The application program classification of library books is built with training data from library books Musi-Caritas Catholic University and the test data is a new book. Applications are made capable of classifying new library book

MOESM4 of Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell line

Additional file 4. Significant pathway analysis of differentially expressed genes (DEGs) related to PHF20

Demographic characteristics.

***<p>p<0.001 compared with normal controls.</p><p>Abbreviations: AD, Alzheimer's disease; DLB, dementia with Lewy body; AF-GP, the atrophic form of general paresis; NC, normal control.</p

Correlations between CSF CysC and CSF Αβ40 and Αβ42 levels.

<p>Abbreviations: AD, Alzheimer's disease; DLB, dementia with Lewy body; AF-GP, the atrophic form of general paresis; NC, normal control; CysC, cystatin C; Αβ, amyloid-β.</p

The serum and CSF CysC levels of dementia patients divided by CDR scores.

<p>No significant differences in serum or CSF CysC levels were observed in patients with AD (A and D), DLB (B and E) and AF-GP (C and F). Statistically significant difference was calculated using one-way ANOVA. Data are means ± SD. Abbreviations: CysC, cystatin C; CDR, Clinical Dementia Rating Scale; AD, Alzheimer's disease; DLB, dementia with Lewy body; AF-GP, the atrophic form of general paresis.</p

The CSF Αβ40 and Αβ42 levels in AD, DLB, AF-GP and normal control subjects.

<p>(A) The levels of CSFΑβ40 were significantly lower in patients with AD and DLB compared to normal controls. There was a trend towards decreased CSF Αβ40 levels in patients with AF-GP compared to normal controls (p = 0.075). (B) The levels of CSF Αβ42 were significantly lower in patients with AD, DLB and AF-GP compared to normal controls. Statistically significant difference was calculated using one-way ANOVA, followed by Bonferroni's post hoc test. Data are means ± SD. Abbreviations: Αβ, amyloid-β protein; AD, Alzheimer's disease; DLB, dementia with Lewy body; AF-GP, the atrophic form of general paresis; NC, normal control. (**p<0.01, ***p<0.001).</p

The CSF and serum CysC levels in AD, DLB, AF-GP and normal control subjects.

<p>(A) The levels of CSF CysC were significantly lower in patients with AD, DLB and AF-GP compared to normal controls. (B) The levels of serum CysC were significantly lower in patients with AF-GP compared to normal controls. (C) The CSF/serum CysC ratios were significantly lower in patients with AD and DLB compared to normal controls. Statistically significant difference was calculated using one-way ANOVA, followed by Bonferroni's post hoc test. Data are means ± SD. Abbreviations: CysC, cystatin C; AD, Alzheimer's disease; DLB, dementia with Lewy body; AF-GP, the atrophic form of general paresis; NC, normal control. (*p<0.05, **p<0.01, ***p<0.001).</p

Scatter plots of the correlations between CSF CysC and CSF Αβ40 and Αβ42 levels.

<p>(A) (C) (D) The CSF CysC levels were positively correlated with CSF Αβ40 levels in AD (r = 0.312, p = 0.026), AF-GP (r = 0.441, p = 0.003) and normal control (r = 0.388, p = 0.034) subjects. (E) (G) (H) The CSF CysC levels were positively correlated with CSF Αβ42 levels in AD (r = 0.306, p = 0.029), AF-GP (r = 0.657, p<0.001) and normal control (r = 0.507, p = 0.004) subjects. (B) (F) No significant correlations were found between CSF CysC and CSF Αβ40 or Αβ42 in patients with DLB (r = 0.021, p = 0.919, and r = 0.037, p = 0.859, respectively). The correlations of the measured values were examined using the Pearson correlation coefficient. Abbreviations: CysC, cystatin C; Αβ, amyloid-β protein; AD, Alzheimer's disease; DLB, dementia with Lewy body; AF-GP, the atrophic form of general paresis; NC, normal control.</p

Clinical data.

***<p>p<0.001 compared with normal controls.</p><p>Abbreviations: AD, Alzheimer's disease; DLB, dementia with Lewy body; AF-GP, the atrophic form of general paresis; NC, normal control; MMSE, Mini Mental State Examination; MoCA, Montreal Cognitive Assessment; ADAS-cog, Alzheimer's Disease Assessment Scale-cognitive subscale; GDS, Geriatric Depression Scale; NPI, Neuropsychiatric Inventory; CDR, Clinical Dementia Rating Scale; GFR, glomerular filtration rate; na, not applicable.</p

Additional file 3: Table S2. of Reliability and validity of the international dementia alliance schedule for the assessment and staging of care in China

Correlation of item scores of IDEAL, Chinese version, against factor scores of CBI. (DOCX 16 kb