Computer Vision-Based Risk Assessment on Heterogeneous Mobile Network Operating Environments

In order to logically prioritize the urgent risks in the heterogeneous mobile network operating environment, we derive environmental factors that can reflect the characteristics of the heterogeneous network operating environment and present them as an improved security risk assessment formula. The prioritized risks derived through this improved risk assessment formula can visually express the severity of the risk by using computer vision. The purpose of this study was to derive environmental factors that can reflect the security control characteristics of various heterogeneous network operating environments and to apply them to security risk evaluation formulas to prioritize urgent risks and easily identify the degree of security risks. In the existing risk assessment formula, risk is calculated based on three indices: the importance of the asset, the vulnerability score, and the threat score. However, two problems were derived from the existing risk assessment. First, the existing risk assessment formula is insufficient to reflect the controlled environment characteristics of each network because the risk level is calculated based on individual assets. Second, if the same systems with the same purpose (same settings) are operated in different heterogeneous network operating environments, they are counted at the same risk level, and action cannot be prioritized quickly. To solve these problems, we propose an indicator called environmental factor (E), which is a combination of three indices. The three indices are "Network Diversity Index (NDI), network Zone Separation Index (ZSI) and Control Level Index (CLI)". NDI expressed the diversity of networks numerically. ZSI is a numerical expression of the complexity of the network zone. CLI is a numerical expression of the degree of network control level. Results of the study showed that the risk assessment formula applying the proposed risk assessment factors can quickly identify urgent risks and act quickly. In heterogeneous mobile network operating environment in which numerous systems are operated, really urgent risks among the risks calculated through the proposed risk assessment will be handled quickly and logically

Computer Vision-Based Risk Assessment on Heterogeneous Mobile Network Operating Environments

In order to logically prioritize the urgent risks in the heterogeneous mobile network operating environment, we derive environmental factors that can reflect the characteristics of the heterogeneous network operating environment and present them as an improved security risk assessment formula. The prioritized risks derived through this improved risk assessment formula can visually express the severity of the risk by using computer vision. The purpose of this study was to derive environmental factors that can reflect the security control characteristics of various heterogeneous network operating environments and to apply them to security risk evaluation formulas to prioritize urgent risks and easily identify the degree of security risks. In the existing risk assessment formula, risk is calculated based on three indices: the importance of the asset, the vulnerability score, and the threat score. However, two problems were derived from the existing risk assessment. First, the existing risk assessment formula is insufficient to reflect the controlled environment characteristics of each network because the risk level is calculated based on individual assets. Second, if the same systems with the same purpose (same settings) are operated in different heterogeneous network operating environments, they are counted at the same risk level, and action cannot be prioritized quickly. To solve these problems, we propose an indicator called environmental factor (E), which is a combination of three indices. The three indices are "Network Diversity Index (NDI), network Zone Separation Index (ZSI) and Control Level Index (CLI)". NDI expressed the diversity of networks numerically. ZSI is a numerical expression of the complexity of the network zone. CLI is a numerical expression of the degree of network control level. Results of the study showed that the risk assessment formula applying the proposed risk assessment factors can quickly identify urgent risks and act quickly. In heterogeneous mobile network operating environment in which numerous systems are operated, really urgent risks among the risks calculated through the proposed risk assessment will be handled quickly and logically

Association of nonalcoholic fatty liver disease and venous thromboembolic disease in healthy adults in Korea: a nationwide study

Abstract Nonalcoholic fatty liver disease (NAFLD) can lead to a prothrombotic state, which significantly burdens public healthcare systems. This study investigated the relationship between NAFLD and the incidence of venous thromboembolism (VTE) in Korea using National Health Insurance Service-National Sample Cohort 2.0 data. A population-based retrospective cohort analysis was conducted on 472,212 healthy individuals who underwent national health check-ups in Korea from 2009 to 2014. NAFLD was defined using the fatty liver index (FLI). Multivariate Cox proportional hazards regression models were used to analyze the association between FLI and VTE. Individuals were categorized into four quartiles according to FLI values (first quartile [Q1], 0–5.7; second quartile [Q2], 5.8–15.3; third quartile [Q3], 15.4–37.2; and fourth quartile [Q4], > 37.2). The incidence of VTE tended to increase with increasing FLI values (Q1, 598 [0.5%]; Q2, 1,033 [0.9%]; Q3, 1,443 [1.2%]; and Q4, 1,425 [1.2%]). In the age- and sex-adjusted multivariate model, the hazard ratio (HR) (95% confidence interval [CI]) was 1.47 (1.33‒1.62) for Q4 compared with Q1. After adjusting for clinical variables with P < 0.1 in the univariate analyses, the HR (95% CI) was 1.45 (1.30‒1.62) for Q4 compared with Q1. FLI was related to VTE risk, as confirmed after adjusting for other risk factors

The Development of Ship Watch Keeping Supporting Aids

This study deals with the development of ship watch keeping supporting aids that will be useful for ship deck officers in recognizing navigational harmful obstacles such as sea marks and small floating objects on the sea. The developed watch keeping supporting aids is made up of four components; a composite video sensor to produce video signal, a laser distance measuring part, a Pan/Tilt part and a central control part. The system was installed in a ship in order to verify its performance of the recognition ability on the sea. The comparison was made between the recognition ability of the system and that of watch keeping deck officers’. The image from the watch keeping supporting system was found to be more recognizable than that of a binocular telescope within a 5 km distance. The newly suggested system is expected to be used to recognize small dangerous floating objects more easily when navigation deck officers have a duty of watch keeping for navigation especially near harbor area

Serum Levels of PCSK9 Are Associated with Coronary Angiographic Severity in Patients with Acute Coronary Syndrome

BackgroundProprotein convertase subtilisin/kexin type 9 (PCSK9) is a circulating protein that promotes degradation of the low density lipoprotein receptor. PCSK9 has emerged as a target for lipid-lowering therapy, but the predictive value of the serum level of PCSK9 for the severity of coronary disease is largely unknown.MethodsFrom December 2009 to July 2012, 121 individuals who underwent coronary angiography (CAG) because of clinically suspected acute coronary syndrome were enrolled in this study. Serum levels of PCSK9 and metabolic parameters were measured. SYNTAX (SYNergy between percutaneous coronary intervention with [paclitaxel-eluting] TAXUS stent and cardiac surgery) and GRACE (Global Registry of Acute Coronary Events) scores were calculated.ResultsIndividuals with CAG lesions (n=100) had significantly higher levels of PCSK9 than those without lesions (n=21). The study population was stratified into three groups according to serum levels of PCSK9. The odds radio for occurrence of one or more CAG lesions was significantly higher in the group with the highest level of PCSK9 (odds ratio, 7.468; P=0.011) than in the group with the lowest level of PCSK9. Serum PCSK9 was positively associated with the number of involved coronary arteries. Multivariable linear regression indicated that levels of PCSK9 were positively correlated with GRACE risk scores and SYNTAX scores.ConclusionSerum PCSK9 concentrations are higher in patients with coronary artery lesions, and are associated with SYNTAX and GRACE scores, suggesting that PCSK9 is a potential biomarker of the severity of coronary artery disease

Table_1_The novel bio-SYNTAX scoring system for predicting the prognosis of patients undergoing percutaneous coronary intervention with left main coronary artery disease.DOCX

BackgroundSimple and effective risk models incorporating biomarkers associated with left main coronary artery (LMCA) stenosis are limited. This study aimed to validate the novel Bio-Clinical SYNTAX score (Bio-CSS) incorporating N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with LMCA stenosis.MethodsPatients who underwent percutaneous coronary intervention (PCI) for LMCA stenosis using a drug-eluting stent (n = 275) were included in the study. We developed the Bio-CSS incorporating NT-proBNP and validated the ability of the Bio-CSS to predict major adverse cardiac events (MACEs) and compared its performance to that of the SYNTAX score (SS) and SS II. The MACEs were defined as death, non-fatal myocardial infarction (MI), and repeat revascularizations.ResultsThe Bio-CSS (34.7 ± 18.3 vs. 51.9 ± 28.4, p ConclusionIn patients who underwent PCI for LMCA stenosis, the novel Bio-CSS improved the discrimination accuracy of established combined scores, such as SS and SS II. The addition of NT-proBNP to the clinical and angiographic findings in the Bio-CSS could potentially provide useful long-term prognostic information in these patients.</p

Image_1_The novel bio-SYNTAX scoring system for predicting the prognosis of patients undergoing percutaneous coronary intervention with left main coronary artery disease.JPEG

BackgroundSimple and effective risk models incorporating biomarkers associated with left main coronary artery (LMCA) stenosis are limited. This study aimed to validate the novel Bio-Clinical SYNTAX score (Bio-CSS) incorporating N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with LMCA stenosis.MethodsPatients who underwent percutaneous coronary intervention (PCI) for LMCA stenosis using a drug-eluting stent (n = 275) were included in the study. We developed the Bio-CSS incorporating NT-proBNP and validated the ability of the Bio-CSS to predict major adverse cardiac events (MACEs) and compared its performance to that of the SYNTAX score (SS) and SS II. The MACEs were defined as death, non-fatal myocardial infarction (MI), and repeat revascularizations.ResultsThe Bio-CSS (34.7 ± 18.3 vs. 51.9 ± 28.4, p ConclusionIn patients who underwent PCI for LMCA stenosis, the novel Bio-CSS improved the discrimination accuracy of established combined scores, such as SS and SS II. The addition of NT-proBNP to the clinical and angiographic findings in the Bio-CSS could potentially provide useful long-term prognostic information in these patients.</p

Long‐term impact of angiotensin receptor‐neprilysin inhibitor based on short‐term treatment response in heart failure

Abstract Aims The long‐term effect of angiotensin receptor–neprilysin inhibitor (ARNI) remains uncertain in patients who have experienced improvements in left ventricular (LV) systolic function or significant LV reverse remodelling following a certain period of treatment. It is also unclear how ARNI performs in patients who have not shown these improvements. This study aimed to assess the impact of prolonged ARNI use compared with angiotensin‐converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) in patients with and without significant treatment response after 1 year of heart failure (HF) treatment. Methods and results The present study enrolled patients with HF with reduced ejection fraction (HFrEF) who were treated with either ARNI or ACEIs/ARBs within 1 year of undergoing index echocardiography. After 1 year of treatment, patients were reclassified into the following groups: (i) patients with HF with improved ejection fraction and persistent HFrEF and (ii) patients with and without LV reverse remodelling based on the follow‐up echocardiography. The effect of ARNI versus that of ACEIs/ARBs in each group was assessed from the time of categorizing into new groups using the composite event of all‐cause mortality and HF hospitalization. A total of 671 patients with HFrEF (age, 66.4 ± 14.1 years; males, 66.8%) were included, and 133 (19.8%) composite events of death and rehospitalization for HF were observed during the follow‐up (median follow‐up, 44 [interquartile range, 34–51] months). ARNI had a significantly lower event rate than ACEIs/ARBs in patients with HF with improved ejection fraction (7.0% vs. 30.4%, P = 0.020) and those with persistent HFrEF (17.6% vs. 49.7%, P < 0.001). Irrespective of whether patients exhibited LV reverse remodelling (15.8% vs. 31.1%, P = 0.001) or not (15.0% vs. 54.9%, P < 0.001), ARNIs were associated with a significantly lower event rate than ACEIs/ARBs. Conclusions Regardless of significant treatment response measured by either LVEF or LV reverse remodelling after 1 year of treatment, the extended utilization of ARNI demonstrated a more favourable prognosis than that of ACEIs/ARBs in patients with HFrEF