Food Insecurity: Rudimentary Education for Local Youth (FIREFLY)

As service-learning becomes recognized as a significant teaching-learning tool for college students, the authors of this article came together to apply for the Purdue University Service-Learning Sustainability Projects Grant. Upon receiving the grant, with the encouragement of Professor Jane Krause and Food Finders Food Bank, the student authors created a project focused on food insecurity education in West Lafayette, Indiana. The main objective was to develop and teach a series of lessons on food insecurity and sustainability to middle school students using interactive activities. A team of Purdue students from various backgrounds was recruited to assist in planning and to act as student mentors. They partnered with Mrs. Caren Walker, a family and consumer science teacher at Klondike Middle School, on this project. The team of Purdue students taught the five lessons for her three classes of eighth grade students. The most competitive teams from these classes came to present their posters, made throughout the project, at the Purdue Engagement and Service-Learning Summit on March 1, 2017

Semiclassical Moser--Trudinger inequalities

We extend the Moser--Trudinger inequality of one function to systems of orthogonal functions. Our results are asymptotically sharp when applied to the collective behavior of eigenfunctions of Schr\"odinger operators on bounded domains.Comment: 18 page

The impact of admission diagnosis on gastric emptying in critically ill patients

Introduction Disturbed gastric emptying (GE) occurs commonly in critically ill patients. Admission diagnoses are believed to influence the incidence of delayed GE and subsequent feed intolerance. Although patients with burns and head injury are considered to be at greater risk, the true incidence has not been determined by examination of patient groups of sufficient number. This study aimed to evaluate the impact of admission diagnosis on GE in critically ill patients. Methods A retrospective review of patient demographics, diagnosis, intensive care unit (ICU) admission details, GE, and enteral feeding was performed on an unselected cohort of 132 mechanically ventilated patients (94 males, 38 females; age 54 ± 1.2 years; admission Acute Physiology and Chronic Health Evaluation II [APACHE II] score of 22 ± 1) who had undergone GE assessment by 13C-octanoic acid breath test. Delayed GE was defined as GE coefficient (GEC) of less than 3.20 and/or gastric half-emptying time (t50) of more than 140 minutes. Results Overall, 60% of the patients had delayed GE and a mean GEC of 2.9 ± 0.1 and t50 of 163 ± 7 minutes. On univariate analysis, GE correlated significantly with older age, higher admission APACHE II scores, longer length of stay in ICU prior to GE measurement, higher respiratory rate, higher FiO2 (fraction of inspired oxygen), and higher serum creatinine. After these factors were controlled for, there was a modest relationship between admission diagnosis and GE (r = 0.48; P = 0.02). The highest occurrence of delayed GE was observed in patients with head injuries, burns, multi-system trauma, and sepsis. Delayed GE was least common in patients with myocardial injury and non-gastrointestinal post-operative respiratory failure. Patients with delayed GE received fewer feeds and stayed longer in ICU and hospital compared to those with normal GE. Conclusion Admission diagnosis has a modest impact on GE in critically ill patients, even after controlling for factors such as age, illness severity, and medication, which are known to influence this function.Nam Q Nguyen, Mei P Ng, Marianne Chapman, Robert J Fraser and Richard H Hollowa

Feasibility of Tomotherapy-Based Image-Guided Radiotherapy to Reduce Aspiration Risk in Patients with Non-Laryngeal and Non-Pharyngeal Head and Neck Cancer

Purpose: The study aims to assess the feasibility of Tomotherapy-based image-guided radiotherapy (IGRT) to reduce the aspiration risk in patients with non-laryngeal and non-hypopharyngeal cancer. A retrospective review of 48 patients undergoing radiation for non-laryngeal and non-hypopharyngeal head and neck cancers was conducted. All patients had a modified barium swallow (MBS) prior to treatment, which was repeated one month following radiotherapy. Mean middle and inferior pharyngeal dose was recorded and correlated with the MBS results to determine aspiration risk

Feasibility of intensity-modulated and image-guided radiotherapy for functional organ preservation in locally advanced laryngeal cancer

Purpose: The study aims to assess the feasibility of intensity-modulated and image-guided radiotherapy (IMRT, and IGRT, respectively) for functional preservation in locally advanced laryngeal cancer. A retrospective review of 27 patients undergoing concurrent chemoradiation for locally advanced laryngeal cancers (8 IMRT, 19 IGRT) was undertaken. In addition to regular clinical examinations, all patients had PET imaging at 4 months and 10 months after radiotherapy, then yearly. Loco-regional control, speech quality and feeding-tube dependency were assessed during follow-up visits. Results: At a median follow-up of 20 months (range 6-57 months), four out of 27 patients (14.8%) developed local recurrence and underwent salvage total laryngectomy. One patient developed distant metastases following salvage surgery. Among the 23 patients who conserved their larynx with no sign of recurrence at last follow-up, 22 (95%) reported normal or near normal voice quality, allowing them to communicate adequately. Four patients (14.8%) had long-term tube feeding-dependency because of severe dysphagia (2 patients) and chronic aspiration (2 patients, with ensuing death from aspiration pneumonia in one patient). Conclusions and Clinical Relevance: Functional laryngeal preservation is feasible with IMRT and IGRT for locally advanced laryngeal cancer. However, dysphagia and aspiration remain serious complications, due most likely to high radiation dose delivery to the pharyngeal musculatures. © 2012 Nguyen et al

Retrieval of material properties of monolayer transition-metal dichalcogenides from magnetoexciton energy spectra

Reduced exciton mass, polarizability, and dielectric constant of the surrounding medium are essential properties for semiconduction materials, and they can be extracted recently from the magnetoexciton energies. However, the acceptable accuracy of the previously suggested method requires very high magnetic intensity. Therefore, in the present paper, we propose an alternative method of extracting these material properties from recently available experimental magnetoexciton s-state energies in monolayer transition-metal dichalcogenides (TMDCs). The method is based on the high sensitivity of exciton energies to the material parameters in the Rytova-Keldysh model. It allows us to vary the considered material parameters to get the best fit of the theoretical calculation to the experimental exciton energies for the $1s$, $2s$, and $3s$ states. This procedure gives values of the exciton reduced mass and 2D polarizability. Then, the experimental magnetoexciton spectra compared to the theoretical calculation gives also the average dielectric constant. Concrete applications are presented only for monolayers WSe$_2$ and WS$_2$ from the recently available experimental data. However, the presented approach is universal and can be applied to other monolayer TMDCs. The mentioned fitting procedure requires a fast and effective method of solving the Schr\"{o}dinger of an exciton in monolayer TMDCs with a magnetic field. Therefore, we also develop such a method in this study for highly accurate magnetoexciton energies.Comment: 8 pages, 4 figures, 4 table

Dosimetric Selection for Helical Tomotherapy Based Stereotactic Ablative Radiotherapy for Early-Stage Non-Small Cell Lung Cancer or Lung Metastases

Background No selection criteria for helical tomotherapy (HT) based stereotactic ablative radiotherapy (SABR) to treat early stage non-small cell lung cancer (NSCLC) or solitary lung metastases has been established. In this study, we investigate the dosimetric selection criteria for HT based SABR delivering 70 Gy in 10 fractions to avoid severe toxicity in the treatment of centrally located lesions when adequate target dose coverage is desired. Materials and Methods 78 HT-SABR plans for solitary lung lesions were created to prescribe 70 Gy in 10 fractions to the planning target volume (PTV). The PTV was set to have ≥95% PTV receiving 70 Gy in each case. The cases for which dose constraints for ≥1 OAR could not be met without compromising the target dose coverage were compared with cases for which all target and OAR dose constraints were met. Results There were 23 central lesions for which OAR dose constraints could not be met without compromising PTV dose coverage. Comparing to cases for which optimal HT-based SABR plans were generated, they were associated with larger tumor size (5.72±1.96 cm vs. 3.74±1.49 cm, p\u3c0.0001), higher lung dose, increased number of immediately adjacent OARs ( 3.45±1.34 vs. 1.66±0.81, p\u3c0.0001), and shorter distance to the closest OARs (GTV: 0.26±0.22 cm vs. 0.88±0.54 cm, p\u3c0.0001; PTV 0.19±0.18 cm vs. 0.48±0.36 cm, p = 0.0001). Conclusion Delivery of 70 Gy in 10 fractions with HT to meet all the given OAR and PTV dose constraints are most likely when the following parameters are met: lung lesions ≤3.78 cm (11.98 cc), ≤2 immediately adjacent OARs which are ≥0.45 cm from the gross lesion and ≥0.21 cm from the PTV