2 research outputs found
Adherence to oral HIV pre-exposure prophylaxis among female sex workers in Kampala, Uganda
Introduction: In Kampala Uganda, female sex workers (FSWs) have high
HIV prevalence (33%). Oral PrEP is a novel HIV prevention intervention
that offers hope to decrease HIV incidence in key populations
especially among FSWs. Studies have shown that with poor adherence,
oral PrEP has no efficacy, and therefore adherence to PrEP is critical
among FSWs to maximize HIV prevention. However, implementation data on
adherence to PrEP among FSWs is limited so this study sought to assess
adherence to PrEP. Specifically, we sought to 1) determine the level of
adherence to PrEP among FSWs, and 2) determine factors associated with
PrEP adherence. Methods: This cross-sectional study was conducted from
November to December 2018; 126 FSWs using PrEP were interviewed using a
questionnaire. Adherence was categorically defined as high adherence
and low adherence. Logistic regression was done. Results: Using
long-term contraception methods (OR 0.06, 95% CI: 0.04-0.77) and not
using condoms with clients (OR 0.07, 95% CI: 0.01-0.42) were negatively
associated with high PrEP adherence. Conclusion: Barriers to PrEP
adherence need to be addressed for successful PrEP implementation to
improve adherence going forward. Service care providers should
reinforce positive behaviors such as use of condoms devotedly during
PrEP breaks