961 research outputs found

    A geospatial solution using a TOPSIS approach for prioritizing urban projects in Libya

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    © 2018 Proceedings - 39th Asian Conference on Remote Sensing: Remote Sensing Enabling Prosperity, ACRS 2018 The world population is growing rapidly; consequently, urbanization has been in an increasing trend in many developing cities around the globe. This rapid growth in population and urbanization have also led to infrastructural development such as transportation systems, sewer, power utilities and many others. One major problem with rapid urbanization in developing/third-world countries is that developments in mega cities are hindered by ineffective planning before construction projects are initiated and mostly developments are random. Libya faces similar problems associated with rapid urbanization. To resolve this, an automating process via effective decision making tools is needed for development in Libyan cities. This study develops a geospatial solution based on GIS and TOPSIS for automating the process of selecting a city or a group of cities for development in Libya. To achieve this goal, fifteen GIS factors were prepared from various data sources including Landsat, MODIS, and ASTER. These factors are categorized into six groups of topography, land use and infrastructure, vegetation, demography, climate, and air quality. The suitability map produced based on the proposed methodology showed that the northern part of the study area, especially the areas surrounding Benghazi city and northern parts of Al Marj and Al Jabal al Akhdar cities, are most suitable. Support Vector Machine (SVM) model accurately classified 1178 samples which is equal to 78.5% of the total samples. The results produced Kappa statistic of 0.67 and average success rate of 0.861. Validation results revealed that the average prediction rate is 0.719. Based on the closeness coefficient statistics, Benghazi, Al Jabal al Akhdar, Al Marj, Darnah, Al Hizam Al Akhdar, and Al Qubbah cities are ranked in that order of suitability. The outputs of this study provide solution to subjective decision making in prioritizing cities for development

    The Relationship between Heart Rate Variability and Adiposity Differs for Central and Overall Adiposity

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    While frank obesity is associated with reduced HRV, indicative of poorer autonomic nervous system (ANS) function, the association between body mass index (BMI) and HRV is less clear. We hypothesized that effects of adiposity on ANS are mostly mediated by visceral fat and less by subcutaneous fat; therefore, centrally distributed adipose tissue, that is, waist circumference (WC), should be more strongly associated with HRV than overall adiposity (BMI). To examine this hypothesis, we used data collected in a subset of the Baltimore Longitudinal Study of Aging to compare strength of association between HRV and WC to that of HRV and BMI. Time domain HRV variables SDNN (standard deviation of successive differences in normal-to-normal (N-N) intervals) and RMSSD (root mean square of successive differences in N-N intervals) were calculated from 24-hour Holter recordings in 159 participants (29–96 years). Increasing WC was associated with decreasing SDNN and RMSSD in younger but not older participants (P value for WC-by-age interaction = 0.003). BMI was not associated with either SDNN or RMSSD at any age. In conclusion, central adiposity may contribute to sympathetic and parasympathetic ANS declines early in life

    White Blood Cell Count and Mortality in the Baltimore Longitudinal Study of Aging

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    ObjectivesWe investigated the secular trend in white blood cell (WBC) count and the relationship between WBC count and mortality between 1958 and 2002.BackgroundThe WBC count is a clinical marker of inflammation and a strong predictor of mortality. Limited data exist on the WBC count secular trend and the relationship between WBC and mortality.MethodsOne thousand eighty-three women and 1,720 men were evaluated longitudinally in the Baltimore Longitudinal Study of Aging. Blood samples and medical information were collected at the study entry and every 2 years during follow-up visits. The WBC count and all-cause, cardiovascular, and cancer mortality were assessed.ResultsA downward trend in WBC count was observed from 1958 to 2002. The secular downward trend was independent of age, gender, race, smoking, body mass index, and physical activity. The WBC count was nonlinearly associated with all-cause mortality and almost linearly associated with cardiovascular mortality. Participants with baseline WBC <3,500 cells/mm3and WBC >6,000 cells/mm3had higher mortality than those with 3,500 to 6,000 WBC/mm3. Within each WBC group, age-adjusted mortality rates declined in successive cohorts from the 1960s to the 1990s. Participants who died had higher WBC than those who survived, and the difference was statistically significant within 5 years before death.ConclusionsOur study provides evidence for a secular downward trend in WBC count over the period from 1958 to 2002. Higher WBC counts are associated with higher mortality in successive cohorts. We found no evidence that the decline of age-specific mortality rates that occurred from 1960 to 2000 was attributable to a secular downward trend in WBC

    Carboxilatos hidroxilados de rodio II (gluconato, lactobionato e lactato). Síntesis, caracterización y ensayos de citotoxicidad in vitro

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    The synthesis, characterization and biological assays of two new rhodium carboxy- lates carbohydrate derivatives, rhodium gluconate Rh2(Gli)4 and lactobionate Rh2(Lab)4 are herein described. These compounds showed good water solubility and low toxicity for fe- male mice in dosis higher than 200 mg/kg. The cytostatic activity was carried out in vitro against K-562 cells and compared with other hydroxyl carboxylate, the rhodium lactate Rh2(Lac)4, which was recently described and synthesized in our laboratory by an alternative route. The derivatives showed low in vitro activity but due to the low toxicity they can be considered as promising carboxylate carriers of antineoplasic drugs that can form adducts in the axial positions.Son descritos la sintésis, la caracterización y los ensayos biológicos de dos nuevos Carboxilatos de Rodio derivados de carbohidratos: gluconato y lactobionato de rodio (II). Estos compuestos mostraron una buena solubilidad en agua y baja toxicidad in vivo en rato- nes (hembras) a dosis mayores de 200 mg/kg. La actividad citostática fue evaluada en célu- las K-562 y comparada con otro carboxilato hidroxilado, como el lactato de rodio, Rh2(Lac)4, el cual fue recientemente descrito y sintetizado por una ruta alternativa. La acti- vidad antitumoral de los derivados de carboidratos fue baja, sin embargo por la baja toxici- dad los carboxilatos son prometedores como portadores de fármacos antineoplásicos que puedem formar aductos en posición axial
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