Mejoras en el proceso productivo y modernización mediante sustitución y tecnologías limpias en un molino de arroz

The rice production includes the agriculture, productive, and distribution process. There are the need of the integral analysis, with the purpose of improve their efficient and competitively. In this contex are presented improvements that impact in the production and productivity in milling rice sited in Arequipa region. For that is making a productive process diagnostic, a benchmarking with the sector enterprises, and the introduction of more celan production concepts.La producción de arroz, que comprende la agricultura, procesos productivos y distribución, requiere de análisis a fin de mejorar su eficiencia y competitividad. En este contexto, en el presente trabajo, se propone mejoras que redunden en la producción y productividad en un molino de arroz ubicado en la región Arequipa. Para tal fin se realiza un diagnóstico del proceso productivo, un benchmarking con las empresas del sector, así como se introducen conceptos de producción más limpia

High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile

Healthy metabolic measures in humans are associated with longevity. Dysregulation leads to metabolic syndrome (MetS) and negative health outcomes. Recent exceptional longevity (EL) genome wide association studies have facilitated estimation of an individual’s polygenic risk score (PRS) for EL. We tested the hypothesis that individuals with high ELPRS have a low prevalence of MetS. Participants were from five cohorts of middle-aged to older adults. The primary analyses were performed in the UK Biobank (UKBB) (n = 407,800, 40–69 years). Replication analyses were undertaken using three Australian studies: Hunter Community Study (n = 2122, 55–85 years), Older Australian Twins Study (n = 539, 65–90 years) and Sydney Memory and Ageing Study (n = 925, 70–90 years), as well as the Swedish Gothenburg H70 Birth Cohort Studies (n = 2273, 70–93 years). MetS was defined using established criteria. Regressions and meta-analyses were performed with the ELPRS and MetS and its components. Generally, MetS prevalence (22–30%) was higher in the older cohorts. In the UKBB, high EL polygenic risk was associated with lower MetS prevalence (OR = 0.94, p = 1.84 × 10–42) and its components (p < 2.30 × 10–8). Meta-analyses of the replication cohorts showed nominal associations with MetS (p = 0.028) and 3 MetS components (p < 0.05). This work suggests individuals with a high polygenic risk for EL have a healthy metabolic profile promoting longevity

High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile

Healthy metabolic measures in humans are associated with longevity. Dysregulation leads to metabolic syndrome (MetS) and negative health outcomes. Recent exceptional longevity (EL) genome wide association studies have facilitated estimation of an individual's polygenic risk score (PRS) for EL. We tested the hypothesis that individuals with high ELPRS have a low prevalence of MetS. Participants were from five cohorts of middle-aged to older adults. The primary analyses were performed in the UK Biobank (UKBB) (n = 407,800, 40-69 years). Replication analyses were undertaken using three Australian studies: Hunter Community Study (n = 2122, 55-85 years), Older Australian Twins Study (n = 539, 65-90 years) and Sydney Memory and Ageing Study (n = 925, 70-90 years), as well as the Swedish Gothenburg H70 Birth Cohort Studies (n = 2273, 70-93 years). MetS was defined using established criteria. Regressions and meta-analyses were performed with the ELPRS and MetS and its components. Generally, MetS prevalence (22-30%) was higher in the older cohorts. In the UKBB, high EL polygenic risk was associated with lower MetS prevalence (OR = 0.94, p = 1.84 × 10-42) and its components (p < 2.30 × 10-8). Meta-analyses of the replication cohorts showed nominal associations with MetS (p = 0.028) and 3 MetS components (p < 0.05). This work suggests individuals with a high polygenic risk for EL have a healthy metabolic profile promoting longevity

Coronavirus disease-19 in the older persons : recommendations for a comprehensive inpatient care

Desde la declaración del estado de pandemia por la Organización Mundial de la Salud, el número de casos de COVID-19 en México y el mundo se ha incrementado de forma exponencial, al igual que el de fallecimientos. Las personas mayores(PM)se han considerado un grupo poblacional particularmente vulnerable a múltiples desenlaces adversos, lo cual podría explicarse, entre otros factores, por los cambios fisiológicos relacionados con el envejecimiento y una mayor carga de enfermedades. Dadas la situación actual y la ausencia de un tratamiento curativo, el éxito de la atención hospitalaria en las PM con COVID-19 depende no solo de las medidas de apoyo, sino de la atención integral de los problemas geriátricos adjuntos. El objetivo de esta revisión es emitir consideraciones diagnósticas y recomendaciones prácticas para el tratamiento integral de las PM hospitalizadas por COVID-19Since the World Health Organization declared a pandemic status for coronavirus disease (COVID-19), the number of cases and fatalities in Mexico and the rest of the world have exponentially risen. Older persons (OPs) have been one of the populations particularly identified as vulnerable to diverse negative health-related outcomes, which could be partially explained, by the con tribution of physiological changes related to the aging process, and a higher comorbidity burden. Given the current situation of a surge of cases or a second wave of the pandemic in Latin America, and the absence of a curative treatment, quality inpatient treatment of OP with COVID-19 not only relies on supportive treatment but also comprehensive care of potentially associated geriatric issues. The objective of this narrative review is to provide practical diagnostic and therapeutic considerations for the inpatientcare of OP with COVID-19.Revista Nacional - No indexad