567 research outputs found

    Chern-Simons Reduction and non-Abelian Fluid Mechanics

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    We propose a non-Abelian generalization of the Clebsch parameterization for a vector in three dimensions. The construction is based on a group-theoretical reduction of the Chern-Simons form on a symmetric space. The formalism is then used to give a canonical (symplectic) discussion of non-Abelian fluid mechanics, analogous to the way the Abelian Clebsch parameterization allows a canonical description of conventional fluid mechanics.Comment: 12 pages, REVTeX; revised for publication in Phys Rev D; email to [email protected]

    Initial antimicrobial management of sepsis.

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    Sepsis is a common consequence of infection, associated with a mortality rate > 25%. Although community-acquired sepsis is more common, hospital-acquired infection is more lethal. The most common site of infection is the lung, followed by abdominal infection, catheter-associated blood steam infection and urinary tract infection. Gram-negative sepsis is more common than gram-positive infection, but sepsis can also be due to fungal and viral pathogens. To reduce mortality, it is necessary to give immediate, empiric, broad-spectrum therapy to those with severe sepsis and/or shock, but this approach can drive antimicrobial overuse and resistance and should be accompanied by a commitment to de-escalation and antimicrobial stewardship. Biomarkers such a procalcitonin can provide decision support for antibiotic use, and may identify patients with a low likelihood of infection, and in some settings, can guide duration of antibiotic therapy. Sepsis can involve drug-resistant pathogens, and this often necessitates consideration of newer antimicrobial agents

    Cosmokinetics: A joint analysis of Standard Candles, Rulers and Cosmic Clocks

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    We study the accelerated expansion of the universe by using the kinematic approach. In this context, we parameterize the deceleration parameter, q(z), in a model independent way. Assuming three simple parameterizations we reconstruct q(z). We do the joint analysis with combination of latest cosmological data consisting of standard candles (Supernovae Union2 sample), standard ruler (CMB/BAO), cosmic clocks (age of passively evolving galaxies) and Hubble (H(z)) data. Our results support the accelerated expansion of the universe.Comment: PDFLatex, 15 pages, 12 pdf figures, revised version to appear in JCA

    Antimicrobial resistance in Antarctica: is it still a pristine environment?

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    Although the rapid spread of antimicrobial resistance (AMR), particularly in relation to clinical settings, is causing concern in many regions of the globe, remote, extreme environments, such as Antarctica, are thought to be relatively free from the negative impact of human activities. In fact, Antarctica is often perceived as the last pristine continent on Earth. Such remote regions, which are assumed to have very low levels of AMR due to limited human activity, represent potential model environments to understand the mechanisms and interactions underpinning the early stages of evolution, de novo development, acquisition and transmission of AMR. Antarctica, with its defined zones of human colonisation (centred around scientific research stations) and large populations of migratory birds and animals, also has great potential with regard to mapping and understanding the spread of early-stage zoonotic interactions.[...

    From cosmic deceleration to acceleration: new constraints from SN Ia and BAO/CMB

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    We use type Ia supernovae (SN Ia) data in combination with recent baryonic acoustic oscillations (BAO) and cosmic microwave background (CMB) observations to constrain a kink-like parametrization of the deceleration parameter (qq). This qq-parametrization can be written in terms of the initial (qiq_i) and present (q0q_0) values of the deceleration parameter, the redshift of the cosmic transition from deceleration to acceleration (ztz_t) and the redshift width of such transition (τ\tau). By assuming a flat space geometry, qi=1/2q_i=1/2 and adopting a likelihood approach to deal with the SN Ia data we obtain, at the 68% confidence level (C.L.), that: zt=0.560.10+0.13z_t=0.56^{+0.13}_{-0.10}, τ=0.470.20+0.16\tau=0.47^{+0.16}_{-0.20} and q0=0.310.11+0.11q_0=-0.31^{+0.11}_{-0.11} when we combine BAO/CMB observations with SN Ia data processed with the MLCS2k2 light-curve fitter. When in this combination we use the SALT2 fitter we get instead, at the same C.L.: zt=0.640.07+0.13z_t=0.64^{+0.13}_{-0.07}, τ=0.360.17+0.11\tau=0.36^{+0.11}_{-0.17} and q0=0.530.13+0.17q_0=-0.53^{+0.17}_{-0.13}. Our results indicate, with a quite general and model independent approach, that MLCS2k2 favors Dvali-Gabadadze-Porrati-like cosmological models, while SALT2 favors Λ\LambdaCDM-like ones. Progress in determining the transition redshift and/or the present value of the deceleration parameter depends crucially on solving the issue of the difference obtained when using these two light-curve fitters.Comment: 25 pages, 9 figure

    Sedimentation record in the Konkan-Kerala Basin: implications for the evolution of the Western Ghats and the Western Indian passive margin

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    The Konkan and Kerala Basins constitute a major depocentre for sediment from the onshore hinterland of Western India and as such provide a valuable record of the timing and magnitude of Cenozoic denudation along the continental margin. This paper presents an analysis of sedimentation in the Konkan-Kerala Basin, coupledwith a mass balance study, and numerical modelling of flexural responses to onshore denudational unloading and o¡shore sediment loading in order to test competing conceptual models for the development of high-elevation passive margins. The Konkan-Kerala Basin contains an estimated 109,000 km<sup>3</sup>; of Cenozoic clastic sediment, a volume difficult to reconcile with the denudation of a downwarped rift flank onshore, and more consistent with denudation of an elevated rift flank. We infer from modelling of the isostatic response of the lithosphere to sediment loading offshore and denudation onshore that flexure is an important component in the development of the Western Indian Margin.There is evidence for two major pulses in sedimentation: an early phase in the Palaeocene, and a second beginning in the Pliocene. The Palaeocene increase in sedimentation can be interpreted in terms of a denudational response to the rifting between India and the Seychelles, whereas the mechanism responsible for the Pliocene pulse is more enigmatic

    Rings and bars: unmasking secular evolution of galaxies

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    Secular evolution gradually shapes galaxies by internal processes, in contrast to early cosmological evolution which is more rapid. An important driver of secular evolution is the flow of gas from the disk into the central regions, often under the influence of a bar. In this paper, we review several new observational results on bars and nuclear rings in galaxies. They show that these components are intimately linked to each other, and to the properties of their host galaxy. We briefly discuss how upcoming observations, e.g., imaging from the Spitzer Survey of Stellar Structure in Galaxies (S4G), will lead to significant further advances in this area of research.Comment: Invited review at "Galaxies and their Masks", celebrating Ken Freeman's 70-th birthday, Sossusvlei, Namibia, April 2010. To be published by Springer, New York, editors D.L. Block, K.C. Freeman, & I. Puerari; minor change
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