A case of post dural puncture headache following labour epidural analgesia, managed by sphenopalatine ganglion block

Postpartum headache is a common complaint faced by most obstetricians, with over 39% of women having headache in the first postpartum week. With the increasing use of labour epidural analgesia, the incidence of postdural puncture headache (PDPH) due to inadvertent dural puncture is 0.5-1%. Most treatment modalities relieve the symptoms of PDPH by minimizing compensatory cerebral vasodilatation, or by sealing the dural puncture site. Treatment options include, conservative, pharmacological, and the gold standard, epidural blood patch (EBP). EBP is invasive and may result in rare however, severe complications. Sphenopalatine ganglion block (SPGB) has been proposed as a non-invasive intervention for PDPH, which has minimal adverse effects, which can be performed bedside. Here we are reporting a case of PDPH, following labour epidural analgesia which was effectively managed by a sphenopalatine block.

Studies on Extraction, Microencapsulation and Potential Applications of Ginger Oleoresin

685-691The aim of this study is to develop stable formulations of ginger oleoresin using microencapsulation and emulsification technology. Different formulations of microencapsulated ginger oleoresin were formulated using spray drying technique. The advantage of encapsulation is that the formulations are water soluble unlike the oleoresin; which helps in reducing the use of solvents and promotes the use of natural product and widens its application range. The wall materials like polyvinylpyrrolidone (PVP) and maltodextrin (MD) showed the maximum encapsulation efficiency of 81.043%. The flow properties of microencapsulated powder were studied by analyzing the compressibility index and Hausner ratio for different combination of wall materials. The optimization of microemulsion was studied using pseudo-ternary phase diagram and the microemulsion with the maximum area was found in 3:1 (Surfactant: Co-Surfactant) ratio of Tween80- Propylene Glycol with caprylic-capric triglycerides as the oil phase and rest is the water phase. The ginger oleoresin diffusion study was carried out using Franz diffusion cell to study the active permeability, and stability of the formulations

Studies on Extraction, Microencapsulation and Potential Applications of Ginger Oleoresin

The aim of this study is to develop stable formulations of ginger oleoresin using microencapsulation and emulsification technology. Different formulations of microencapsulated ginger oleoresin were formulated using spray drying technique. The advantage of encapsulation is that the formulations are water soluble unlike the oleoresin; which helps in reducing the use of solvents and promotes the use of natural product and widens its application range. The wall materials like polyvinylpyrrolidone (PVP) and maltodextrin (MD) showed the maximum encapsulation efficiency of 81.043%. The flow properties of microencapsulated powder were studied by analyzing the compressibility index and Hausner ratio for different combination of wall materials. The optimization of microemulsion was studied using pseudo-ternary phase diagram and the microemulsion with the maximum area was found in 3:1 (Surfactant: Co-Surfactant) ratio of Tween80- Propylene Glycol with caprylic-capric triglycerides as the oil phase and rest is the water phase. The ginger oleoresin diffusion study was carried out using Franz diffusion cell to study the active permeability, and stability of the formulations

A comparison of outcomes in ultrasonography guided versus landmark guided corticosteroid injection for the treatment of adhesive capsulitis

Background: Adhesive capsulitis is a debilitating disease in an otherwise healthy individual. Intra-articular corticosteroid injections offer a cost-effective, non-operative treatment option. However, it is currently unclear whether an ultrasound-guided injection relieves the symptoms of shoulder pain more effectively than if the injection was delivered landmark-guided. Methods: Eighty patients with adhesive capsulitis were randomized to two intervention groups - landmark guided and ultrasound (USG) guided. The functional status of the patients was documented prior to the intervention. Following allocation, the intra-articular steroid was administered either under USG guidance or following identification of the site of injection using landmarks. Follow-up was done on day 5, 3 weeks, 6 weeks, and 12 weeks post procedure to document the functional status. Results: The difference in visual analogue score (VAS) between the two arms was found to be statistically significant in favour of the ultrasound guided technique only on day 5 and day 21. On the other hand, the difference in disability of arm, shoulder, and hand (DASH) score between the 2 arms was found to be statistically significant in favour of the ultrasound guided technique on day 5, 21, 42 and 84. Finally, in our study, both shoulder flexion and abduction on day 84 achieved a statistically significant improvement, favouring the ultrasound guided arm. Conclusions: Ultrasound guided corticosteroid injections may offer modestly better short-term functional outcome and symptom relief when compared with landmark guided corticosteroids

Prospective nutritional, therapeutic, and dietary benefits of camel milk making it a viable option for human consumption: Current state of scientific knowledge

For over five thousand years, people in Asia and Africa have known about the health benefits of camel milk. Thus, it is used not only as a food source but also as a medicine. The similarities between camel milk and human milk have been scientifically proven. Camel milk is unique among ruminant milk because it is high in vitamins C and E and low in sugar and cholesterol. Still, it contains a wide variety of beneficial minerals (including sodium, potassium, iron, copper, zinc, and magnesium), besides being rich in several nutrients, including monounsaturated and polyunsaturated fatty acids, serum albumin, lactoferrin, immunoglobulins, lysozyme and the hormone insulin. Because of these components, many medical professionals now recommend camel milk as a treatment for various human ailments. It has been demonstrated to be effective in treating gastrointestinal issues, Type 1 diabetes, and food allergies. As a bonus, camel milk has been utilized to cure autism, lower cholesterol, prevent psoriasis, heal inflammation, aid tuberculosis patients, boost the body's natural defences, and impede the spread of cancer cells. Those who have problems digesting lactose may still be able to tolerate it. Conversely, camel milk can also help reduce an excessively high bilirubin, globulin, and granulocyte count. Drinking camel milk does not affect the erythrocyte sedimentation rate, hemoglobin concentration, and leukocyte count. The proteins in camel milk have an adequate ratio of critical amino acids. Immunoglobulins, which fight disease, are contained inside, and their small size allows antigens to penetrate and boosts the immune system's efficacy. This article highlights the health benefits and medicinal uses of camel milk