PARASITIC INFECTIONS AND CANCERS: ASSOCIATIVE STUDY

It’s estimated that over 15% of malignancies worldwide are often attributed to infections; the figures are higher in developing countries to the extent of twenty-two compared to about 7% in developing countries. The incidence of malignancy an infectious cause is about 1.2 million cases per annum. This also implies that a minimum of a number of the cancers are preventable and will be a thrust area for research.This paper deals with the connection between parasitic infections and carcinogenesis and therefore the possible mechanisms involved

SCREENING OF DIFFERENT PARTS OF ANNONA SQUAMOSA EXTRACT FOR ANTIBACTERIAL ACTIVITY

Annona squamosa belongs to the family Annonaceae, commonly known as custard apple. A comparative antibacterial activity of methanolic leaf and seed cotyledon extracts of Annona squamosa were evaluated against three bacterial strains namely Bacillus subtilis, Escherichia coli, staphylococcus aureus using agar well diffusion method. Maximum inhibition was found with 40 mg/ml concentration of methanolic leaf and seed cotyledon extracts against all the tested organisms under investigation. The minimum inhibitory concentrations were determined by disk diffusion method. To find the compound responsible for antibacterial activity thin layer chromatography was done.The FTIR analysis was performed represented the presence of various functional groups. The phytochemical analysis was performed. The study suggests that the leaf and seed cotyledon extracts of Annona squamosa are promising the development of phytomedicine for antimicrobial properties