A Morphological Study of"Microfold" Cells of Lymphoid Aggregative Tissue in the Small Intestine of the Chicken

The morphology of lymphoid aggregative tissue of the small intestine was studied in the Japanese bantam chicken. Lymphoid aggregative tissue were composed of leaf-like villi unlike those in mammals. In the present study, these lymphoid aggregative tissues histologically were identified as Peyer\u27s patches. Light and electron microscopy of the covering epithelium of the Peyer\u27s patches showed that the cells had morphologically the same features of "Microfold" ("M") cells previously described in mammalian species. The authors demonstrated that the "M" cells of birds were not limited to the bursa of Fabricius, but also existed in the covering epithelium of the Peyer\u27s patches in the small intestine. The proportion of "M" cells enfolding lymphoid cells much in mature chickens (18%) than in mature rats (100%)

内視鏡的に虫体を摘出しえた胃アニサキス症と回虫症 : 7症例の検討

川崎医科大学附属病院開設以来12年間に7例の胃内寄生虫を経験した.6例はアニサキスで,穿刺部位は胃体部大彎でびらんを伴っていた.全員鯖を摂取しており11月に多発していた.内視鏡的に虫体を摘出した.1例は回虫で,胃体部大彎で観察され,内視鏡的に摘出した.胃内で回虫を観察することはまれである.From 1973 to 1985, 7 cases of parasites were experienced in our department. In 6 cases of anisakiasis, the worms caused inflammation and erosion of the greater curvature of body of the stomach. All patients had eaten Mackerel. Gastric anisakiasis were frequently encountered in November. In all cases, the worms were removed by endoscopy. In 1 case of ascariasis, the worm was observed in the greater curvature of body of the stomach and was removed by endoscopy. It is rare that the worm of ascariasis is observed in the stomach

虚血性大腸炎 : 10症例の検討

川崎医科大学附属病院開設以来12年10カ月間に経験した虚血性大腸炎について集計した.(1)内視鏡検査あるいは注腸造影にて経過を追うことのできた例は10例あり,平均53歳で男性5例,女性5例であった.(2)病変部位は,S状結腸,下行結腸に多く,注腸造影では拇指圧痕,小嚢形成が,内視鏡では縦走潰瘍が特徴的であった.(3)診断のための検査は全例7日以内に施行され9例で診断可能であった.治癒までの期間は,平均29.9日であった.From 1973 to 1985, 10 cases of ischemic colitis, followed up by endoscopical examination or barium enema, were experienced. Various kinds of clinical analyses were performed on these patients and the following results were obtained. (1) The average age of these patients was 53 years old. There was no sex difference. (2) Most of the lesions were seen in the sigmoid and descending colon. Characteristic features of this disease in the barium enema are thumb printing and sacculation. Colonoscopically, the main characteristic of this disease is longitudinal ulcer. (3) In all cases, the examination was performed within 7 days from the onset of this disease and in 9 cases a diagnosis of ischemic colitis was obtained. The mean period from the onset of this disease to the healing stage was 29.9 days

大腸癌と内視鏡検査 : 12年間の臨床統計

過去12年間に当科に入院した大腸癌患者を集計し,大腸癌の現状と内視鏡施行状況について検討を加え,以下の結論を得た.(1)大腸癌患者は174名で,女性42.0%,男性58.0%であり,年齢は17歳より84歳におよび平均年齢は60.1歳で50歳代,60歳代に多かった.(2)多発例は8%に認められ,発生部位では,直腸・S状結腸の病変で過半数を占めていた.(3)臨床症状は,下血,腹痛,下痢,便秘が多く認められた.(4)形態は,限局潰瘍型・浸潤潰瘍型が多く,大きさは3cm以上の例が多く,深達度では,201病変のうち47病変が早期癌であった.治療は,外科的治療が85.6%を占め,内視鏡的ポリペクトミーを受けた例は12例であった.(5)内視鏡検査は140例に施行され,病変の存在診断は93.4%で可能であり,そのうち93.5%で癌と診断可能であった.大きさ1cm未満の病変では,内視鏡検査は注腸造影検査よりも診断能力が優れていた.From 1973 to 1985, 174 patients with cancer of the colon and rectum were admitted to the Division of Gastroenterology, Kawasaki Medical School. Various kinds of clinical analyses were performed on these patients, including colonoscopy. The following results were obtained. (1) The distribution by sex was 42.0% women and 58.0% men. The patients ranged in age from 17 to 84 years. The mean age was 60.1 years old and the peak occurred in the 50-60 year age group. (2) Multiple lesions occurred in 8% of all cases. More than half of the lesions occurred in the rectum and sigmoid colon. (3) The symptoms of melena, abdominal pain, diarrhea, and constipation were often recognized in these patients. (4) Localized or invasive ulceration types of the colorectal cancer were common and the lesions were usually more than 3cm in diameter. Forty-seven lesions were classified as early cancer. Almost all of patients received surgical treatment and an endoscopical polypectomy was performed on 12 patients. (5) Colonoscopic examinations of 140 patients were performed. Of the total 93.4% of the lesions could be detected and 93.5% of those, which were detected by colonofiberscopy, could be diagnosed as cancer. Especially in the case of lesions of less than 1cm in diameter, colonofiberscopic diagnosis proved more effective than a barium enema