Some Properties of Li-Yorke Chaos

In this paper we study Li-Yorke chaos in linear operator on Banach space, in addition to  establishing some basic properties of Li-Yorke chaos and explanation when the operator be Li-Yorke chaos or not. We also prove...............

Prevalence of Legionella among pneumonia patients and environmental water samples in an Egyptian University Hospital

AbstractObjectives: to diagnose Legionella infection in community- acquired pneumonia (CAP) cases admitted to chest department of Zagazig University Hospital and in hospital- acquired pneumonia (HAP) patients hospitalized in the emergency and surgery ICU, to determine incidence of these disease condition and to identify risk factors. Another objective was to determine the occurrence of Legionella genus in the water of these departments.Subjects and methods: one hundred pneumonic patients; 50 patients with CAP and 50 with HAP were the subject of this laboratory-based, comparative cross sectional study. Full clinical history and lower respiratory tract specimens were collected from each patient. Water samples were taken from 25 water outlets. DNA was extracted by QIAamp DNA Mini Kit, and real time PCR amplification of 16s r-RNA gene was used for diagnosis of Legionella genus. Risk factors were analyzed by logistic regression analysis.Results: Legionella genus was identified in eight out of 50 patients of CAP (16%), and ten out of 50 patients with HAP (20%). As regards CAP, Legionella was prevalent in old- age, smoker males, with diabetes mellitus (DM) and/or chronic obstructive pulmonary disease (COPD). Gastrointestinal tract (GIT) and neurological manifestations were the main presentations. Seventy-five percent needed ICU admission. Concerning HAP, hospitalization for more than ten days and having a stroke or head trauma were significant risk factors. Ten out of the 25 water samples tested were positive for Legionella genus; seven samples were from the chest department and three were from emergency ICU. No water-contamination with Legionella was found in the surgery ICU.Discussion: diagnosis of Legionella should be considered for both CAP and HAP in our locality. Periodic surveillance for detection of that genus with subsequent disinfection of water sources when indicated should be carried out

Stability and Existence of Solutions for a Tripled Problem of Fractional Hybrid Delay Differential Equations

The purpose of this paper is to determine the existence of tripled fixed point results for the tripled symmetry system of fractional hybrid delay differential equations. We obtain results which support the existence of at least one solution to our system by applying hybrid fixed point theory. Similar types of stability analysis are presented, including Ulam–Hyers, generalized Ulam–Hyers, Ulam–Hyers–Rassias, and generalized Ulam–Hyers–Rassias. The necessary stipulations for obtaining the solution to our proposed problem are established. Finally, we provide a non-trivial illustrative example to support and enhance our analysis.This work was supported in part by the Basque Government under Grant IT1555-22

ASSESSMENT OF VITAMIN D THERAPY EFFECT ON INFLAMMATORY MARKERS IN PEDIATRIC PATIENTS WITH TYPE I DIABETIC

Objective: The objective of this study is to estimate the effect of Vitamin D3 supplementation on endogenous Vitamin D3 level and inflammatory biomarkers in newly diagnosed pediatric patients.Methods: The patients were given oral Vitamin D3, and they divided into three groups: The first group (25 healthy pediatrics), the second group (25 newly diagnosed pediatric patients) treated with daily insulin regimen only, and the third group (25 newly diagnosed pediatric patients) treated with Vitamin D3 (2000 IU/day) with daily insulin regimen; all patients were treated for 90 days; and blood samples were taken at baseline and after 45 days and 90 days of starting Vitamin D3 to assess its potential effect on the levels of Vitamin D, serum calcium, serum alkaline phosphatase levels, and other inflammatory markers.Results: The results of the current study showed that serum IL-1β significantly declined in patients receiving Vitamin D3, while serum Vitamin D3, serum calcium, and interleukins-4 were significantly increased in patients receiving Vitamin D3.Conclusion: Vitamin D3 in a daily dose of 2000 IU/day for 90 days results in favorable immune response and increase of serum Vitamin D3 for pediatric new diagnosed Type 1 diabetes mellitus patients

Sponge media drying using a swirling fluidized bed dryer

Surface preparation today has seen the introduction of sponge media as an alternative product against the traditionally used abrasive materials. Being soft and elastic, the sponge media reduces air borne emission significantly during surface preparation with capability to be re-used. However the environmental conditions limit the sponge media usage whereby wet surroundings prohibit the re-use of the sponge without being dried properly. This study proposes the swirling fluidized bed dryer as a novel drying technique for sponge media. Batch experiments were conducted to study the bed’s hydrodynamics followed by drying studies for three bed loadings of 0.5 kg, 0.75 kg and 1.0 kg at three drying temperatures of 80°C, 90°C and 100°C. It was found that, minimum fluidization velocities for the wet sponge particles were found to be 1.342, 1.361 and 1.382 m/s with minimum swirling velocities of 1.400, 1.469 and 1.526 m/s. Drying times were recorded between 6 to 16 minutes depending on bed loading and drying temperature. Smaller bed weights exhibits faster drying with constant-rate drying period while higher drying temperature and larger bed load resulted in falling-rate drying period. Thin layer modelling for the falling-rate region indicates that Verma et. al model provides the best fit for the present experimental data with coefficient of determination, R2 = 0.98773, root mean square error, RMSE = 0.05048, residuals = 0.3442 and reduced chi-square, χ2 = 0.00254. The effective diffusivity, Deff, for 0.5 kg bed load was found to be 3.454 x 10-9 m2/s and 1.751 x 10-9 m2/s for 0.75 kg bed load. In conclusion, SFBD was found to be a viable and efficient method in drying of sponge media for various industrial applications particularly surface preparation

PDMS-based dual-channel pneumatic microactuator using sacrificial molding fabrication technique

This paper presents a novel polydimethylsiloxane-based dual-channel bellows-structured pneumatic actuator, fabricated through sacrificial molding technique. A finite element analysis was performed to find the optimum structure and analyze the bending performance of the square-bellows actuator. The actuator was fabricated using acrylonitrile butadiene-styrene-based sacrificial mold to form the channel and bellow structures with an overall actuator size of 5 × 5 × 27.6 mm3. The experimental validation has revealed that the actuator attained a smooth bi-directional bending motion with maximum angles of -25° and 35° and force of -0.168 and 0.212 N under left and right channel actuation, respectively, at 100 kPa pressure. Hence, the state-of-the-art dual channels square-bellows actuator was able to achieve an optimum bi-directional bending with low input pressure, which would push the boundaries of soft robotics towards the development of more safe and flexible robotic surgical tools

Study of CD25 expression on leukemic cells: a prognostic factor in acute myeloid leukemia

BackgroundAcute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by a clonal expansion of myeloid blasts. Treatment strategies of patients with AML are based on various prognostic factors, including age and performance status of the patient, as well as cytogenetic and molecular characteristics of the leukemic clone.Our aim was to study the expression of cluster of differentiation (CD)25 in adult Egyptian patients with newly diagnosed AML and to assess its prognostic relevance. MethodsThis study was conducted on 50 newly diagnosed AML patients at the Hematology Unit, Internal Medicine Department, Alexandria Main University Hospital. All patients were subjected to full history taking, thorough clinical examination, and laboratory investigations, including detection of CD25 expression on blast cells by flow cytometry. Conventional karyotyping was done on 11 patients at the time of diagnosis. ResultsIn our study group, 12 patients were positive for CD25 expression, and this positivity was associated with worse overall survival and shorter leukemia-free survival. On evaluating the response to treatment among CD25-positive AML patients with normal karyotype, they had lower complete remission rates and higher relapse and death rates. ConclusionsExpression of CD25 in AML patients at presentation can be considered a poor independent prognostic factor

A novel algorithm for dynamic student profile adaptation based on learning styles

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.E-learning recommendation systems are used to enhance student performance and knowledge by providing tailor- made services based on the students’ preferences and learning styles, which are typically stored in student profiles. For such systems to remain effective, the profiles need to be able to adapt and reflect the students’ changing behaviour. In this paper, we introduce new algorithms that are designed to track student learning behaviour patterns, capture their learning styles, and maintain dynamic student profiles within a recommendation system (RS). This paper also proposes a new method to extract features that characterise student behaviour to identify students’ learning styles with respect to the Felder-Silverman learning style model (FSLSM). In order to test the efficiency of the proposed algorithm, we present a series of experiments that use a dataset of real students to demonstrate how our proposed algorithm can effectively model a dynamic student profile and adapt to different student learning behaviour. The results revealed that the students could effectively increase their learning efficiency and quality for the courses when the learning styles are identified, and proper recommendations are made by using our method

A Review on Adverse Drug Reaction Detection Techniques

The detection of adverse drug reactions (ADRs) is an important piece of information for determining a patient’s view of a single drug. This study attempts to consider and discuss this feature of drug reviews in medical opinion-mining systems. This paper discusses the literature that summarizes the background of this work. To achieve this aim, the first discusses a survey on detecting ADRs and side effects, followed by an examination of biomedical text mining that focuses on identifying the specific relationships involving ADRs. Finally, we will provide a general overview of sentiment analysis, particularly from a medical perspective. This study presents a survey on ADRs extracted from drug review sentences on social media, utilizing and comparing different techniques

4D printing parameters optimisation for bi-stable soft robotic gripper design

Four-dimensional (4D) printing is an emerging additive manufacturing (AM) technology that adds a time-dependent reconfiguration dimension to three-dimensional (3D) printed products. It enables the creation of on-demand, dynamically controllable shapes, or properties in response to external stimuli such as temperature, magnetic field, and light. Thermally responsive structures are among the most popular types of currently available 4D-printed structures due to their convenience. However, applications like soft robots are hindered by the temperature-sensitive structures' stagnating actuation. This research was driven by a requirement for a rapid and effective design and optimisation strategy for 4D-printed bi-stable thermally responsive structures for use in soft robotics. In this study, the response surface method (RSM) optimization with the aid of numerical solutions was used to investigate effective parameters in the design of a bi-stable, 4D-printed soft robotic gripper. This approach is proposed to accelerate the actuation of thermally responsive shape-morphing structures that can be controlled by the in situ strains and post-manufacturing heat stimuli as variable parameters. By using RSM solution the individual effects as well as the coupling effects of variable parameters on the output responses, including the maximum strain energy and the average distance between the clamps of the structure, are evaluated. The obtained results can be employed to develop the designation and improve the acceleration of soft robotic grippers such as fast buckling and bending, which is desirable for soft robotic applications