20 research outputs found
Application of 1Dâ2D coupled modeling in water quality assessment: A case study in Ca Mau Peninsula, Vietnam
Š 2018 Elsevier Ltd A few 1D and 2D models are used to simulate and calculate the water level and water quality regarding four state variable (DO, NH4, NO3, and BOD) observations in the main rivers and coastal estuaries on the Ca Mau peninsula. This study calibrates and validates 1D and 2D models during the dry and flood seasons for 2014 and 2015, as well as assesses water quality in coastal estuaries during the dry and flood season of 2016 by using a 2D model. The calibration and validation results of the hydrodynamic 1D and 2D models show that there is a high degree of conformity regarding the phase and amplitude of water level at observing stations with mean absolute error (MAE) ranges from 0.05 m to 0.37 m. The RMSEâobservation standard deviation ratio (RSR) vary from 0.12 to 0.64, and the percent bias (PBIAS) is from â8.9% to 3.2%. Calibration and validation of water quality parameter (DO, NH4, NO3, and BOD5 concentration) results have a high correlation coefficient during both the dry and flood season of 2014 and 2015. The standards, originating from the National Technical Regulation on Surface Water quality and on Coastal Water Quality, are used to evaluate pollutant concentrations in estuaries in the study area during the dry and flood seasons of 2016. The water quality parameters contain DO (4.6 mg/lâ7.9 mg/l) and BOD (4.6 mg/lâ10.7 mg/l) concentrations over the National Technical Regulation on Surface and Coastal Water Quality and the A1 limit with DO (>4 mg/l) and BOD5 (4 mg/l) on surface water quality for domestic water use in the dry and flood seasons. The calculated results will help managers make better plans for aquaculture and aquatic conservation zones in coastal estuaries in the future
Human case of Streptococcus suis serotype 16 infection.
Streptococcus suis infection is an emerging zoonosis in Southeast Asia. We report a fatal case of S. suis serotype 16 infection in a Vietnamese man in 2001
Streptococcus suis meningitis in adults in Vietnam.
BACKGROUND: Streptococcus suis infection is an emerging zoonosis in Asia. We determined the detailed epidemiological, clinical, and microbiological characteristics of S. suis meningitis in adults. METHODS: We prospectively studied 450 patients with suspected bacterial meningitis. Four hundred thirty-five (96.7%) of the patients participated in a trial to determine the effect of adjunctive dexamethasone treatment. For patients with S. suis infection, bacterial DNA load at hospital admission and during treatment was analyzed in cerebrospinal fluid specimens using quantitative real-time polymerase chain reaction. S. suis strains were characterized using pulsed-field gel electrophoresis and multilocus sequence typing. Putative virulence factors, including extracellular protein factor, suilysin, and muramidase released protein, were detected using polymerase chain reaction and Western blot assay. Predictors of outcome were identified using logistic regression analysis. RESULTS: S. suis was the most common pathogen and was detected in 151 (33.6%) of the patients. Fifty (33.1%) of these 151 patients reported exposure to pigs or pork. Mortality was low (2.6%; 4 of 151 patients died), but mild to severe hearing loss occurred in 93 (66.4%) of 140 patients. Severe deafness at hospital discharge was associated with age >50 years (odds ratio, 3.65; 95% confidence interval, 1.15-11.6), a strain carrying the epf gene (odds ratio, 3.42; 95% confidence interval, 1.02-11.4), and dexamethasone therapy (odds ratio, 0.23; 95% confidence interval, 0.06-0.78) but was not associated with cerebrospinal fluid bacterial DNA load. Bacterial DNA was still detectable in 58 (63%) of 92 cerebrospinal fluid samples after 6-10 days of antimicrobial treatment. Ninety-one of 92 S. suis strains had serotype 2. Thirty-three (36%) of these epidemiologically unrelated strains belonged to 1 pulsed-field gel electrophoresis cluster of multilocus sequence type 1, indicating clonal spread. CONCLUSION: S. suis serotype 2 is the most frequent cause of bacterial meningitis in adults in southern Vietnam and is associated with substantial morbidity attributable to hearing loss
Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area
Nguyen Duy Hung,1,2,* Nguyen Duy Linh,3,4,* Nguyen Ha Vi,1 Nguyen Thi Van Anh,5 Nguyen Dinh Hieu,1,6 Duong Dai Ha,3,7 Nguyen Minh Duc8 1Department of Radiology, Hanoi Medical University, Hanoi, Vietnam; 2Department of Radiology, Viet Duc Hospital, Hanoi, Vietnam; 3Department of Surgery, Hanoi Medical University, Hanoi, Vietnam; 4Department of Surgery, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam; 5Department of Radiology, Hanoi Medical University Hospital, Hanoi, Vietnam; 6Department of Radiology, Ha Dong General Hospital, Ha Noi, Vietnam; 7Neurosurgery Center, Viet Duc Hospital, Hanoi, Vietnam; 8Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam*These authors contributed equally to this workCorrespondence: Nguyen Minh Duc, Department of Radiology, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Ward 12 District 10, Ho Chi Minh City, 700000, Vietnam, Email [email protected]: This study aimed to assess the predictive value of preoperative diffusion tensor imaging (DTI) data for surgical outcomes of patients with supratentorial glioma in the motor function area.Patients and Methods: This is a retrospective study of 43 patients receiving navigation-guided surgery for histopathologically demonstrated supratentorial glioma in the motor function area. All patients underwent preoperative 3 Tesla magnetic resonance imaging examinations with conventional and DTI sequences. Data on preoperative imaging and pre- and postoperative clinical characteristics of patients were retrospectively collected. Univariate and multivariate linear regressions were applied to analyze the relationships between preoperative parameters and pre- and postoperative muscle strength and the Karnofsky Performance Status (KPS) score.Results: Fourteen patients had low-grade gliomas and 29 had high-grade gliomas. Although the corticospinal tract (CST) score did not differ significantly between tumor grades, edema and deviation were common in low-grade gliomas (64.3%), while destroyed and infiltrated lesions were common in high-grade gliomas (58.6%). Muscle strength improved after surgery in the deviated tract group (40%) more than in the infiltrated tract group (33.3%). Two independent indices, preoperative muscle strength (p =Â 0.000) and glioma-to-CST distance (p =Â 0.001), were linearly related to postoperative muscle strength. The preoperative KPS score was the only indicator that affected the postoperative KPS score (p =Â 0.000).Conclusion: DTI should be considered in surgical management of supratentorial gliomas in the motor function area to determine the appropriate surgical strategy and predict the nature of the tumor and postoperative motor function.Keywords: diffusion tensor imaging, supratentorial glioma, preoperative planning, surgical outcomes, motor corte
Population Estimation and Trappability of the European Badger (Meles meles): Implications for Tuberculosis Management.
peer-reviewedEstimates of population size and trappability inform vaccine efficacy modelling and are required for adaptive management during prolonged wildlife vaccination campaigns. We present an analysis of mark-recapture data from a badger vaccine (Bacille CalmetteâGue´ rin) study in Ireland. This study is the largest scale (755 km2) mark-recapture study ever undertaken with this species. The study area was divided into three approximately equalâsized zones, each with similar survey and
capture effort. A mean badger population size of 671 (SD: 76) was estimated using a closed-subpopulation model (CSpM) based on data from capturing sessions of the entire area and was consistent with a separate multiplicative model. Minimum number alive estimates calculated from the same data were on average 49â51% smaller than the CSpM estimates, but these are considered severely negatively biased when trappability is low. Population densities derived from the CSpM estimates were 0.82â1.06 badgers km22, and broadly consistent with previous reports for an adjacent area. Mean trappability was
estimated to be 34â35% per session across the population. By the fifth capture session, 79% of the adult badgers caught
had been marked previously. Multivariable modelling suggested significant differences in badger trappability depending on zone, season and age-class. There were more putatively trap-wary badgers identified in the population than trap-happy badgers, but wariness was not related to individualâs sex, zone or season of capture. Live-trapping efficacy can vary significantly amongst sites, seasons, age, or personality, hence monitoring of trappability is recommended as part of an adaptive management regime during largeâscale wildlife vaccination programs to counter biases and to improve efficiencies.Department of Agriculture, Food and the MarineTeagasc Walsh Fellowship Programm