37 research outputs found

    How do trypanosomes change gene expression in response to the environment?

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    Osteoporosis in HFE2 juvenile hemochromatosis. A case report and review of the literature

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    Juvenile hemochromatosis (JH) is a severe form of hemochromatosis, which involves rapid iron overload and leads to organ damage, typically before the age of 30. We report a single case of a 25-year-old man suffering from juvenile hemochromatosis, with aggressive clinical manifestations, typically characterized by transaminasemia and progressive erectile dysfunction, due to hypogonadotropic hypogonadism. The clinical case appears interesting, as the patient also had secondary osteoporosis accompanied by increased bone resorption, which prevalently affected trabecular bone. Approximately 6 months after normalization of serum ferritin levels was achieved by frequent phlebotomies, he became eugonadal and bone mineral density of the lumbar spine increased. Our observations suggest that osteoporosis might occur in the state of JH even at a young age, mainly due to the deprivation of sex steroids and the direct tissue toxicity of iron

    Optimal Speed Scaling with a Solar Cell

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    We consider the setting of a sensor that consists of a speed-scalable processor, a battery, and a solar cell that harvests energy from its environment at a time-invariant recharge rate. The processor must process a collection of jobs of various sizes. Jobs arrive at different times and have different deadlines. The objective is to minimize the *recharge rate*, which is the rate at which the device has to harvest energy in order to feasibly schedule all jobs. The main result is a polynomial-time combinatorial algorithm for processors with a natural set of discrete speed/power pairs.Comment: extended abstract to appear at COCOA'1

    Unsteady Magnetopause Reconnection Under Quasi-Steady Solar Wind Driving.

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    The intrinsic temporal nature of magnetic reconnection at the magnetopause has been an active area of research. Both temporally steady and intermittent reconnection have been reported. We examine the steadiness of reconnection using space-ground conjunctions under quasi-steady solar wind driving. The spacecraft suggests that reconnection is first inactive, and then activates. The radar further suggests that after activation, reconnection proceeds continuously but unsteadily. The reconnection electric field shows variations at frequencies below 10 mHz with peaks at 3 and 5 mHz. The variation amplitudes are ∼10-30 mV/m in the ionosphere, and 0.3-0.8 mV/m at the equatorial magnetopause. Such amplitudes represent 30%-60% of the peak reconnection electric field. The unsteadiness of reconnection can be plausibly explained by the fluctuating magnetic field in the turbulent magnetosheath. A comparison with a previous global hybrid simulation suggests that it is the foreshock waves that drive the magnetosheath fluctuations, and hence modulate the reconnection
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