93 research outputs found

    Switching magnetic vortex core by a single nanosecond current pulse

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    In a ferromagnetic nanodisk, the magnetization tends to swirl around in the plane of the disk and can point either up or down at the center of this magnetic vortex. This binary state can be useful for information storage. It is demonstrated that a single nanosecond current pulse can switch the core polarity. This method also provides the precise control of the core direction, which constitutes fundamental technology for realizing a vortex core memory.Comment: 13 pages, 4 figure

    Current-driven resonant excitation of magnetic vortex

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    A magnetic vortex core in a ferromagnetic circular nanodot has a resonance frequency originating from the confinement of the vortex core. By the micromagnetic simulation including the spin-transfer torque, we show that the vortex core can be resonantly excited by an AC (spin-polarized) current through the dot and that the resonance frequency can be tuned by the dot shape. The resistance measurement under the AC current successfully detects the resonance at the frequency consistent with the simulation.Comment: 16 pages, 4 figure

    留学生とのカウンセリングにおける言語的/非言語的コミュニケーション

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    When seeing international students, we tend to be conscious of the problem of language skills. However, it is not easy to arrange enough staffs who are fluent in foreign languages in each students supporting facility. Therefore, finding better ways to support international students without enough language skills is also important. In this paper, I presented clinical case vignett with a international student. Then, based on Beebe and Lachmann’s dyadic systems theory, I discussed how verval/nonverval interaction was going on in our relationship.Although it was difficult to develop mutual understanding verbally, we interacted fully innonverbal level. Regulating speaking speed, nodding, facial expression and so forth had a really important function to regulate our arousal level. It shows that even if we don’t have enough language skills, it would not matter for international students as long as we are able to communicate smoothly in nonverbal level

    Ependymoma associated protein Zfta is expressed in immature ependymal cells but is not essential for ependymal development in mice

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    The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF‑κB signalling, RELA (ZFTA‑RELA), is expressed in more than two‑thirds of supratentorial ependymoma (ST‑EPN‑RELA), but ZFTA¿s expression profile and functional analysis in multiciliated ependymal (E1) cells have not been examined. Here, we showed the mRNA expression of mouse Zfta peaks on embryonic day (E) 17.5 in the wholemount of the lateral walls of the lateral ventricle. Zfta was expressed in the nuclei of FoxJ1‑positive immature E1 (pre‑E1) cells in E18.5 mouse embryonic brain. Interestingly, the transcription factors promoting ciliogenesis (ciliary TFs) (e.g., multicilin) and ZFTA‑RELA upregulated luciferase activity using a 5′ upstream sequence of ZFTA in cultured cells. Zftatm1/tm1 knock‑in mice did not show developmental defects or abnormal fertility. In the Zftatm1/tm1 E1 cells, morphology, gene expression, ciliary beating frequency and ependymal flow were unaffected. These results suggest that Zfta is expressed in pre‑E1 cells, possibly under the control of ciliary TFs, but is not essential for ependymal development or flow. This study sheds light on the mechanism of the ZFTA‑RELA expression in the pathogenesis of ST‑EPNRELA: Ciliary TFs initiate ZFTA‑RELA expression in pre‑E1 cells, and ZFTA‑RELA enhances its own expression using positive feedback

    Dynamical pinning of domain wall in magnetic nanowire induced by Walker breakdown

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    Transmission probability of a domain wall through a magnetic nanowire is investigated as a function of the external magnetic field. Very intriguing phenomenon is found that the transmission probability shows a significant drop after exceeding the threshold driving field, which contradicts our intuition that a domain wall is more mobile in the higher magnetic field. The micromagnetics simulation reveals that the domain wall motion in the wire with finite roughness causes the dynamical pinning due to the Walker breakdown, which semi-quantitatively explains our experimental results.Comment: 17 pages, 4 figure

    Targeted Proteomics of Isolated Glomeruli from the Kidneys of Diabetic Rats: Sorbin and SH3 Domain Containing 2 Is a Novel Protein Associated with Diabetic Nephropathy

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    To evaluate proteins associated with the development of diabetic nephropathy, a major cause of the end-stage renal disease, we analyzed protein expression in isolated glomeruli from spontaneous type 2 diabetic (OLETF) rats and their age-matched control littermates (LETO) in the early and proteinuric stages of diabetic nephropathy using QSTAR Elite LC-MS/MS. Among the 191 and 218 proteins that were altered significantly in the OLETF rats, twenty-four were actin cytoskeleton-associated proteins implicated in the formation of stress fibers, and the impairment of actin polymerization, intermediate filaments and microtubules. Importantly, sorbin and SH3 domain containing 2 (SORBS2), which is involved in the formation of stress fibers, was significantly upregulated in both stages of diabetic nephropathy (1.49- and 1.97-fold, resp.). Immunohistochemical and quantitative-PCR analyses revealed upregulation of SORBS2 in podocytes of glomeruli of OLETF rats. Our findings suggested that SORBS2 may be associated with the development of diabetic nephropathy possibility by reorganization of actin filaments

    Honeydew-associated microbes elicit defense responses against brown planthopper in rice

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    Feeding of sucking insects, such as the rice brown planthopper (Nilaparvata lugens; BPH), causes only limited mechanical damage on plants that is otherwise essential for injury-triggered defense responses against herbivores. In pursuit of complementary BPH elicitors perceived by plants, we examined the potential effects of BPH honeydew secretions on the BPH monocot host, rice (Oryza sativa). We found that BPH honeydew strongly elicits direct and putative indirect defenses in rice, namely accumulation of phytoalexins in the leaves, and release of volatile organic compounds from the leaves that serve to attract natural enemies of herbivores, respectively. We then examined the elicitor active components in the honeydew and found that bacteria in the secretions are responsible for the activation of plant defense. Corroborating the importance of honeydew-associated microbiota for induced plant resistance, BPHs partially devoid of their microbiota via prolonged antibiotics ingestion induced significantly less defense in rice relative to antibiotic-free insects applied to similar groups of plants. Our data suggest that rice plants may additionally perceive herbivores via their honeydew-associated microbes, allowing them to discriminate between incompatible herbivores—that do not produce honeydew—and those that are compatible and therefore dangerous

    Probing the spin polarization of current by soft X-ray imaging of current-induced magnetic vortex dynamics

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    Time-resolved soft X-ray transmission microscopy is applied to image the current-induced resonant dynamics of the magnetic vortex core realized in a micronsized Permalloy disk. The high spatial resolution better than 25 nm enables us to observe the resonant motion of the vortex core. The result also provides the spin polarization of the current to be 0.67 +/-0.16 for Permalloy by fitting the experimental results with an analytical model in the framework of the spin-transfer torque.Comment: 13 pages, 3 figure
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