234 research outputs found

    Inductive measurements of third-harmonic voltage and critical current density in bulk superconductors

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    We propose an inductive method to measure critical current density JcJ_c in bulk superconductors. In this method, an ac magnetic field is generated by a drive current I0I_0 flowing in a small coil mounted just above the flat surface of superconductors, and the third-harmonic voltage V3V_3 induced in the coil is detected. We present theoretical calculation based on the critical state model for the ac response of bulk superconductors, and we show that the third-harmonic voltage detected in the inductive measurements is expressed as V3=G3ωI02/JcV_3= G_3\omega I_0^2/J_c, where ω/2π\omega/2\pi is the frequency of the drive current, and G3G_3 is a factor determined by the configuration of the coil. We measured the I0I_0-V3V_3 curves of a melt-textured YBa2Cu3O7δ\rm YBa_2Cu_3O_{7-\delta} bulk sample, and evaluated the JcJ_c by using the theoretical results.Comment: 3 pages, 1 figure, submitted to Appl. Phys. Let

    On the Mechanism of BaSi2 Thin Film Formation on Si Substrate by Vacuum Evaporation

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    AbstractWe report on the formation mechanism of BaSi2 thin film on Si substrate grown by vacuum evaporation using BaSi2 granules as source materials. Since the vapor flux at the initial stage of evaporation is known to be Ba-rich, Si supply from the substrate is of crucial importance to obtain homogeneous BaSi2 thin film. In fact, low substrate temperature and/or thick film deposition led to formation of rough film with voids, and the oxidation proceeded upon exposure to air. We revealed that appropriate choice of substrate temperature, film thickness, and post-growth in-situ annealing can provide enough diffusion of Si and Ba, leading to realization of homogeneous BaSi2 thin film

    ABO-Incompatible Kidney Transplantation

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    Previously, ABO-incompatible kidney transplantation (KTx) was believed to be a “taboo” for immunological reasons. In Japan, the Tokyo Women’s Medical University reported the first successful case of such transplantation, performed on January 19, 1989. Since then, we have been striving to improve the outcome of ABO-incompatible transplantation for a quarter of a century

    Generation of wavelength-tunable few-cycle pulses in the mid-infrared at repetition rates up to 10  kHz

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    We demonstrate a compact and tunable mid-infrared light source that provides carrier-envelope-phase (CEP)-locked pulses at repetition rates from 500 Hz to 10 kHz. The seed pulses were generated by intra-pulse difference frequency mixing of the output of an Yb:KGW regenerative amplifier that had been spectrally broadened by continuum generation using multiple plates. Then, a two-stage optical parametric amplifier was used to obtain output energies of about 100 µJ/pulse for center wavelengths between 2.8 and 3.5 µm. Owing to the intense pulse energies, it was possible to compress the multi-cycle pulses down to two-cycle pulses using YAG and Si plates

    Ecological Dynamics of Broad- and Narrow-Host-Range Viruses Infecting the Bloom-Forming Toxic Cyanobacterium Microcystis aeruginosa

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    アオコ感染性広域・狭域宿主ウイルスの動態 --アオコとウイルスはいかに共存するか--. 京都大学プレスリリース. 2023-02-24.Microcystis aeruginosa is predicted to interact and coexist with diverse broad- and narrow-host-range viruses within a bloom; however, little is known about their affects on Microcystis population dynamics. Here, we developed a real-time PCR assay for the quantification of these viruses that have different host ranges. During the sampling period, total Microcystis abundance showed two peaks in May and August with a temporary decrease in June. The Microcystis population is largely divided into three phylotypes based on internal transcribed sequences (ITS; ITS types I to III). ITS I was the dominant phylotype (66% to 88%) except in June. Although the ITS II and III phylotypes were mostly less abundant, these phylotypes temporarily increased to approximately equivalent abundances of the ITS I population in June. During the same sampling period, the abundances of the broad-host-range virus MVGF_NODE331 increased from April to May and from July to October with a temporary decrease in June, in which its dynamics were in proportion to the increase of total Microcystis abundances regardless of changes in host ITS population composition. In contrast, the narrow-host-range viruses MVG_NODE620 and Ma-LMM01 were considerably less abundant than the broad-host-range virus and generally did not fluctuate in the environment. Considering that M. aeruginosa could increase the abundance and sustain the bloom under the prevalence of the broad-host-range virus, host abundant and diverse antiviral mechanisms might contribute to coexistence with its viruses

    マウスの神経細胞において、Ischemic postconditioningはmitochondrial permeability transition poreとKATPチャネルの開口を介してNMDA受容体電流を低下させる。

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    Ischemic postconditioning (PostC) is known to reduce cerebral ischemia/reperfusion (I/R) injury; however, whether the opening of mitochondrial ATP-dependent potassium (mito-KATP) channels and mitochondrial permeability transition pore (mPTP) cause the depolarization of the mitochondrial membrane that remains unknown. We examined the involvement of the mito-KATP channel and the mPTP in the PostC mechanism. Ischemic PostC consisted of three cycles of 15 s reperfusion and 15 s re-ischemia, and was started 30 s after the 7.5 min ischemic load. We recorded N-methyl-D-aspartate receptors (NMDAR)-mediated currents and measured cytosolic Ca²⁺ concentrations, and mitochondrial membrane potentials in mouse hippocampal pyramidal neurons. Both ischemic PostC and the application of a mito-KATP channel opener, diazoxide, reduced NMDAR-mediated currents, and suppressed cytosolic Ca2+ elevations during the early reperfusion period. An mPTP blocker, cyclosporine A, abolished the reducing effect of PostC on NMDAR currents. Furthermore, both ischemic PostC and the application of diazoxide potentiated the depolarization of the mitochondrial membrane potential. These results indicate that ischemic PostC suppresses Ca²⁺ influx into the cytoplasm by reducing NMDAR-mediated currents through mPTP opening. The present study suggests that depolarization of the mitochondrial membrane potential by opening of the mito-KATP channel is essential to the mechanism of PostC in neuroprotection against anoxic injury.博士(医学)・甲第781号・令和3年3月15日© Springer Science+Business Media, LLC, part of Springer Nature 2020This is a post-peer-review, pre-copyedit version of an article published in Cellular and molecular neurobiology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10571-020-00996-y

    Interference effects in high-order harmonics from colloidal perovskite nanocrystals excited by an elliptically polarized laser

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    Halide perovskite nanocrystals are suitable materials for photonic devices because their highly efficient luminescence can be tuned over a wide wavelength range by changing the nanocrystal composition and size. Here, we report on the high-order harmonic generation in a solution-processed perovskite CsPbBr₃ nanocrystal film that is excited by a strong midinfrared laser. We observe harmonics up to the 13th order, which is ultraviolet light well above the band-gap energy. By using elliptically polarized laser light, we analyze the influence of the sample structure on the intensity of the 5th harmonic. It is also found that the randomness in the orientation of the nanocrystals in the film induces a reduction in the harmonic intensities due to the interference among the harmonics emitted from nanocrystals with different phases. Our observation of high-order harmonics from nanocrystal films opens a way towards the development of an intensity modulator that can be tuned simply by changing the excitation ellipticity

    The 1988-1989 explosive eruption of Tokachi-dake, central Hokkaido, Its sequence and mode

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    On December 16, 1988, after 26 years of dormancy since the last eruption in 1962, Tokachi-dake began to erupt from the 62-II crater. The eruption started with phreatic explosions. Then, on December 19, the activity changed into phreatomagmatic explosions of Vulcanian type and continued intermittently until March 5, 1989. Although the composition of the essential ejecta, mafic andesite, is similar to those of 1926 and 1962 eruptions, the mode of the present eruption is considerably diffrent The present eruption consists of a series of 23 discrete cannon-like explosions, being frequently accompanied with small-scale pyrcclastic surges and flows. The total volume of ejecta amounts to approximately 6×105 m3, of which about 20% is essential ejecta. A complete sequence of events was compiled and distribution maps of the ash-fall, ballistic blocks, and pyroclastic surges and flows were drawn for each of the larger eruptions. The pyrrolastic surges and flows of the present eruption were small scale, low temperature pyroclastic flows, rich in accessory clasts and unaccompanied by sector collapse. Therefore, the sudden melting of snow causing disastrous mudflows, as in the case of the 1926 eruption, fortunately did not occur

    Initial Condition Dependene of Dynamis and Evaporation of Polymer Spallation Partiles Flying in Polymer Ablated Arcs

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    This paper describes the influence of initial conditions for spallation particles flying in polymer ablation arcs on dynamics and evaporation of the polymer spallation particles using the numerical model. Through our previous experiments, we had found micro-sized `spallation particles\u27 ejected from polyamide materials by thermal plasma contact. To obtain the dynamics of spallation particles in polymer ablation arcs, we have developed a numerical model on dynamics of spallation particles flying in the polymer ablated arcs. The influence of pressure inside the polymer ablated arc, the initial particle diameter and the initial velocity of spallation particles were studied as parameters in the present paper. Under the given temperature and gas flow distributions in specified initial conditions, the trajectories of spallation particles flying in the polymer ablated arc were simulated numerically, considering the time variations in the temperature and the diameter of the particles. The results show that the highest flight altitude of the PA6 spallation particle flying in the PA6 ablated arc is affected by the initial particle diameter and velocity remarkably

    Long-term CMV monitoring and chronic rejection in renal transplant recipients

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    IntroductionCytomegalovirus (CMV) is well established to be an independent risk factor for graft loss after kidney transplantation (KTx). Monitoring for CMV in the chronic phase is not defined in the current guideline. The effects of CMV infection, including asymptomatic CMV viremia, in the chronic phase are unclear.MethodsWe performed a single-center retrospective study to investigate incidence of CMV infection in the chronic phase, defined as more than 1 year after KTx. We included 205 patients who received KTx between April 2004 and December 2017. The CMV pp65 antigenemia assays to detect CMV viremia were continuously performed every 1–3 months.ResultsThe median duration of the follow-up was 80.6 (13.1–172.1) months. Asymptomatic CMV infection and CMV disease were observed in 30.7% and 2.9% in the chronic phase, respectively. We found that 10–20% of patients had CMV infections in each year after KTx which did not change over 10 years. The history of CMV infection in the early phase (within 1 year after KTx) and chronic rejection were significantly associated with CMV viremia in the chronic phase. CMV viremia in the chronic phase was significantly associated with graft loss.DiscussionThis is the first study to examine the incidence of CMV viremia for 10 years post KTx. Preventing latent CMV infection may decrease chronic rejection and graft loss after KTx
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