445 research outputs found

    The Doctor and Ovulation Determination

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    Do Progestins Regulate Menstrual Cycles?

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    Cotton insect control (1988)

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    "These recommendations are based on research conducted in Missouri and are designed to provide adequate yet economical pest insect control with a minimum of insecticide applications."--First page.Flernoy G. Jones and Raymond A. Nabors (Department of Entomology, College of Agriculture)Revised 3/88/6

    A STUDY OF FACULTY AND STUDENTS' PERCEIVED USE OF GOOD PRACTICES INSIDE AND OUTSIDE OF DEVELOPMENTAL MATHEMATICS CLASSROOMS

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    In this dissertation, which is written in a journal-ready format, results from three separate but related studies are reported. In the first study the extent to which developmental mathematics faculty (both full-time and adjunct) perceived they used the Seven Principles of Good Practice in Undergraduate Education was explored. Comparisons of median and boxplots indicated that most developmental mathematics faculty reported using most of the principles often or very often, but variability existed on several items. Active Learning items were the least implemented. In the second study comparisons were made between developmental mathematics faculty and their students at one community college on their reported use of the Seven Principles. Patterns observed in the confidence intervals indicated (a) consistent behaviors among students across classes and (b) incongruence among students and their teachers on most items. In the last study, the principle of Student-Faculty Contact was explored by examining how the use of electronic communication influenced the development of student-faculty relationships through the responses of students from one community college. Results indicated that (a) student initiated conversations were correlated to students’ Predicted Outcome Value, (b) instructor immediacy behaviors and students’ reasons for communicating were correlated, and (c) students’ reasons for communication was the largest predictor for students’ Predicted Outcome Value. Personal/Social, Clarification, Efficiency Reasons and Immediacy explained 33.9% of the variance in students’ Predicted Outcome Value. The ÎČ weight and structure coefficient suggested Personal/Social reasons was a possible suppressor

    A trapped-ion local field probe

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    We introduce a measurement scheme that utilizes a single ion as a local field probe. The ion is confined in a segmented Paul trap and shuttled around to reach different probing sites. By the use of a single atom probe, it becomes possible characterizing fields with spatial resolution of a few nm within an extensive region of millimeters. We demonstrate the scheme by accurately investigating the electric fields providing the confinement for the ion. For this we present all theoretical and practical methods necessary to generate these potentials. We find sub-percent agreement between measured and calculated electric field values

    Evaluation of an Afterschool Children’s Healthy Eating and Exercise Program

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    Background: The purpose of this study was to examine the feasibility of the Children’s Healthy Eating and Exercise Program (CHEE) in an afterschool program of an elementary school. Methods:Students in a low-income elementary school were recruited to participate in the program. Thirty-three children were in the intervention group. Twenty-four children in the comparison group were recruited from after school clubs in the same elementary school.The CHEE Program consisted of 18 sessions, featuring nutrition (20 min) and physical activity (40 min) lessons. Nutrition lessons were adapted from the Traffic Light Diet. Other lessons included MyPlate, my refrigerator, my lunchbox, and a healthy foods tasting activity. Multiple physical activities were utilized in the program including soccer, dance, relay races, tag, and other fun games. Data were collected at the beginning and end of the program. Results: Children in both groups reported eating more vegetables at the post-intervention measurement. Children in the intervention group indicated that they learned about healthy eating and new physical activities due to their participation in the program. Conclusions: Future studies are needed to discover barriers to behavior change as well as apply a more rigorous design to examine the impact of the CHEE Program

    MGMT Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical Trials.

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    The methylation status of the O <sup>6</sup> -methylguanine DNA methyltransferase (MGMT) gene promoter is predictive for benefit from temozolomide in glioblastoma (GBM). A clinically optimized cutoff was sought allowing patient selection for therapy without temozolomide, while avoiding to withhold it from patients who may potentially benefit.Experimental Design: Quantitative MGMT methylation-specific PCR data were obtained for newly diagnosed patients with GBM screened or treated with standard radiotherapy and temozolomide in four randomized trials. The pooled dataset was randomly split into a training and test dataset. The unsupervised cutoff was obtained at a 50% probability to be (un)methylated. ROC analysis identified an optimal cutoff supervised by overall survival (OS). For 4,041 patients valid MGMT results were obtained, whereof 1,725 were randomized. The unsupervised cutoff in the training dataset was 1.27 (log <sub>2</sub> [1,000 × (MGMT+1)/ACTB]), separating unmethylated and methylated patients. The optimal supervised cutoff for unmethylated patients was -0.28 (AUC = 0.61), classifying "truly unmethylated" (≀-0.28) and "gray zone" patients (>-0.28, ≀1.27), the latter comprising approximately 10% of cases. In contrast, for patients with MGMT methylation (>1.27) more methylation was not related to better outcome. Both methylated and gray zone patients performed significantly better for OS than truly unmethylated patients [HR = 0.35, 95% confidence interval (CI), 0.27-0.45, P < 0.0001; HR = 0.58, 95% CI, 0.43-0.78, P < 0.001], validated in the test dataset. The MGMT assay was highly reproducible upon retesting of 218 paired samples (R <sup>2</sup> = 0.94). Low MGMT methylation (gray zone) may confer some sensitivity to temozolomide treatment, hence the lower safety margin should be considered for selecting patients with unmethylated GBM into trials omitting temozolomide

    Full capacitance-matrix effects in driven Josephson-junction arrays

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    We study the dynamic response to external currents of periodic arrays of Josephson junctions, in a resistively capacitively shunted junction (RCSJ) model, including full capacitance-matrix effects}. We define and study three different models of the capacitance matrix Cr⃗,r⃗â€ČC_{\vec{r},\vec{r}'}: Model A includes only mutual capacitances; Model B includes mutual and self capacitances, leading to exponential screening of the electrostatic fields; Model C includes a dense matrix Cr⃗,r⃗â€ČC_{\vec{r},\vec{r}'} that is constructed approximately from superposition of an exact analytic solution for the capacitance between two disks of finite radius and thickness. In the latter case the electrostatic fields decay algebraically. For comparison, we have also evaluated the full capacitance matrix using the MIT fastcap algorithm, good for small lattices, as well as a corresponding continuum effective-medium analytic evaluation of a finite voltage disk inside a zero-potential plane. In all cases the effective Cr⃗,r⃗â€ČC_{\vec{r},\vec{r}'} decays algebraically with distance, with different powers. We have then calculated current voltage characteristics for DC+AC currents for all models. We find that there are novel giant capacitive fractional steps in the I-V's for Models B and C, strongly dependent on the amount of screening involved. We find that these fractional steps are quantized in units inversely proportional to the lattice sizes and depend on the properties of Cr⃗,r⃗â€ČC_{\vec{r},\vec{r}'}. We also show that the capacitive steps are not related to vortex oscillations but to localized screened phase-locking of a few rows in the lattice. The possible experimental relevance of these results is also discussed.Comment: 12 pages 18 Postscript figures, REVTEX style. Paper to appear in July 1, Vol. 58, Phys. Rev. B 1998 All PS figures include

    Modeling Single Electron Transfer in Si:P Double Quantum Dots

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    Solid-state systems such as P donors in Si have considerable potential for realization of scalable quantum computation. Recent experimental work in this area has focused on implanted Si:P double quantum dots (DQDs) that represent a preliminary step towards the realization of single donor charge-based qubits. This paper focuses on the techniques involved in analyzing the charge transfer within such DQD devices and understanding the impact of fabrication parameters on this process. We show that misalignment between the buried dots and surface gates affects the charge transfer behavior and identify some of the challenges posed by reducing the size of the metallic dot to the few donor regime.Comment: 11 pages, 7 figures, submitted to Nanotechnolog
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