Synergia of a heparinoid and promethazine hydrochloride against liver cell necrosis

The effects of combined treatment with a heparinoid-sodium pentosan polysulfate - and an antihistamine-promethazine hydrochloride - against thioacetamide-induced rat liver injury were studied. Treatment by promethazine hydrochloride at 0 and 6 hrs by 2.5 and 1.25 mg per 100 g body weight or by 1.5 mg pentosan polysulfate did not afford a real protection against liver injury. The combined, however, of these two incompletely acting schedules treatment inhibited substantially the development of liver cellnecrosis up to 96 hrs. A synergic action of the above protective agents could be supposed. © 1974 Springer-Verlag

Primary causes of perinatal death: An autopsy study of 556 cases in Greek infants

The primary causes of death in 556 autopsy cases of perinatal death during the six years from 1979 through 1984 are discussed. On the basis of the clinical data and gross and microscopic findings, each case was assigned to one of the following categories of primary causes of death: a pulmonary hyaline membrane disease, infection, malformation, anoxia, immaturity, maternal causes, other causes, and unaccounted for. Definitions of Perinatal infant diseases, essential points of diagnosis, and statistics relating to perinatal infant death are also discussed. © 1986, Gustav Fischer Verlag · Stuttgart · New York. All rights reserved