12 research outputs found
Pervasive gaps in Amazonian ecological research
- Author
- Aguiar Daniel Praia Portela de
- Aguiar Hilton Jeferson Alves Cardoso de
- Albernaz Ana Luisa
- Albuquerque Bianca Weiss
- Aleixo Alexandre
- Alencar Luana
- Almeida Daniely da Frota
- Almeida Marllus Rafael Negreiros
- Almeida Morgana
- Almeida Rony Peterson Santos
- Almeida Wanessa Rejane de
- Alvarado Swanni T.
- Alverga Paula Palhares de Polari
- Alves da Rosa Clarissa
- Alves-Martins Fernanda
- Alves-Martins Fernanda
- Amado Lílian Lund
- Amaral Dário Dantas do
- Anacléto Maria José Pinheiro
- Andrade Ana Luiza
- Andrade Rafael Barreto de
- Andrade-Silva Joudellys
- Andresen Ellen
- Andretti Christian Borges
- Andriolo Aline
- André Thiago
- Anjos Diego V.
- Aragão Luiz
- Aragão Luiz
- Arantes Caroline C.
- Arenas Edith Rosario Clemente
- Arrolho Solange
- Arruda Filipe Viegas de
- Assis Rafael Leandro de
- Azara Ludson
- Azevêdo Carlos Augusto Silva de
- Baccaro Fabricio B.
- Baccaro Fabricio B.
- Baider Cláudia
- Baker Timothy R.
- Barbosa Edelcilio Marques
- Barbosa Julianna Freires
- Barbosa Reinaldo Imbrozio
- Barbosa Thiago Augusto Pedroso
- Barlow Jos
- Barlow Jos
- Barni Paulo Eduardo
- Barros Gabriel Gazzana
- Barroso Jorcely G.
- Barthem Ronaldo
- Bastos Douglas
- Bastos Rafael Costa
- Batista Anderson Pedro Bernadina
- Begot Tiago Octavio
- Beiroz Wallace
- Benetti Cesar João
- Benone Naraiana Loureiro
- Bentos Tony Vizcarra
- Berenguer Erika
- Berenguer Erika
- Bispo Pitágoras C.
- Boldrini Rafael
- Bonates Luiz Carlos de Matos
- Borba Gabriel Costa
- Borges Augusto
- Borges Luiz Henrique Medeiros
- Borges Sérgio Henrique
- Braga Danielle de Lima
- Braga Rafael Benzi
- Brando Paulo
- Brasil Leandro Schlemmer
- Brejão Gabriel Lourenço
- Brito Maiara Tábatha da Silva
- Brito Thaline de Freitas
- Brocardo Carlos Rodrigo
- Brown Irving Foster
- Brulinger Luciane Ferreira Barbosa
- Bueno Anderson S.
- Cabeceira Fernando Gonçalves
- Cabette Helena Soares Ramos
- Cabral Guilherme Sampaio
- Cajaiba Reinaldo Lucas
- Callisto Marcos
- Calor Adolfo Ricardo
- Calvão Lenize Batista
- Camargo José Luís
- Camargo Plínio Barbosa de
- Campana Débora Rodrigues de Souza
- Campos Nubia
- Campos-Filho Eduardo Malta
- Cardoso Maira Rodrigues
- Carim Marcelo de Jesus Veiga
- Carmo Guilherme Henrique Pompiano do
- Carniello Maria Antonia
- Carpanedo Rainiellen de Sá
- Carreiras João
- Carvalho Fernanda Antunes
- Carvalho Fernando Geraldo
- Carvalho Fernando Rogério de
- Carvalho Karine Santana
- Carvalho Lidiany Camila da Silva
- Carvalho Lucélia Nobre
- Carvalho Raquel L.
- Carvalho Raquel L.
- Casadei-Ferreira Alexandre
- Casatti Lílian
- Castello Leandro
- Castello Leandro
- Castilho Carolina
- Castro Arlison Bezerra
- Castro Flávio Siqueira de
- Castro Wendeson
- Catarino Michel
- Cavalheiro Larissa
- Cerqueira Silva Július César
- Cerqueira Pablo Vieira
- Cintra Bruno B.L.
- Cochrane Mark A.
- Coelho de Souza Fernanda
- Coelho Luiz de Souza
- Coletti Fabrício
- Cordeiro Carlos Leandro
- Cornelius Cintia
- Correa Anne Sthephane A.S.
- Costa Batista Michela
- Costa Daniel da Silva
- Costa Flavia R.C.
- Costa Flavia R.C.
- Costa Janaina Barbosa Pedrosa
- Costa Jessica Gomes
- Costa Maria Katiane Sousa
- Costa Marília Maria Silva da
- Couceiro Sheyla Regina Marques
- Cravo Jessica Soares
- Crema Luciana Carvalho
- Cruz Paulo Vilela
- Cruz Wesley Jonatar Alves da
- Cunha Erlane José Rodrigues da
- da Rocha Maíra
- da Silva Guimarães José Renan
- da Silva Menger Juliana
- da Silva Elidiomar R.
- da Silva Gustavo Cardoso
- da Silva Júlia Santana
- da Silva Karina Dias
- da Silva Letícia Fernandes
- da Silva Márcio Joaquim
- da Silva Pedro Giovâni
- da Silva Rogério Rosa
- Daly Douglas
- Damasco Gabriel
- Davis Bradley
- de Abreu Jadson Coelho
- de Albuquerque Emília Zoppas
- de Brito Janaina Gomes
- de Faria Falcão Jéssica Caroline
- de Lima Alves Adriana
- de Matos Liliane Stedile
- de Oliveira Melo Lia
- de Resende Bethânia Oliveira
- de Sousa Gorayeb Inocêncio
- de Toledo José Julio
- Delabie Jacques Hubert Charles
- Demarchi Layon Oreste
- Desidério Gleison Robson
- Deus Claudia Pereira de
- Dias Murilo S.
- do Vale Julio Daniel
- Domingues Tomas F.
- Doria Carolina Rodrigues da Costa
- dos Anjos Marcelo Rodrigues
- Douglas Danyhelton
- Duarte Ritter Camila
- Dumas Leandro Lourenço
- Durgante Flavia
- Dutra Dhâmyla Bruna de Souza
- Dutra Silvia Leitão
- Dáttilo Wesley
- d’Horta Fernando Mendonça
- e Gomes Jerrian Oliveira
- e Pérez Raúl Enriqu Pirela
- Edwards David P.
- Elias Fernando
- Elias Fernando
- Emilio Thaise
- Esposito Maria Cristina
- Espírito Santo Nádia Barbosa
- Espírito-Santo Helder M.V.
- Fadini Rodrigo Ferreira
- Fares Ana Luisa
- Faria Ana Paula Justino
- Farias Emanuelle de Sousa
- Feitosa Rodrigo Machado
- Feitosa Yuri
- Feldpausch Ted R.
- Fernandes Itanna Oliveira
- Fernandes Izaias
- Ferreira Aurélia Bentes
- Ferreira Joice
- Ferreira Joice
- Ferreira Leandro Valle
- Ferreira Nelson
- Ferreira-Ferreira Jefferson
- Firmino Viviane
- Flores Bernardo M.
- Florêncio Fernando Prado
- Fontenele Luane
- França Filipe
- França Filipe M.
- Freitas Carlos
- Freitas Madson Antonio Benjamin
- Freitas Marina Guimarães
- Félix Nathalia Silva
- Galuch André V.
- Gama Neto Jaime de Liege
- Gastauer Markus
- Geber Filho Adem Nagibe dos Santos
- Ghidini André Ricardo
- Giacomin Leandro
- Giarrizzo Tommaso
- Giehl Nubia França da Silva
- Godoy Bruno Spacek
- Gomes Vitor Hugo Freitas
- Gontijo Alexandre
- Gonçalves Inês Correa
- Graça Paulo Mauricio de Alencastro
- Griffiths Hannah
- Gris Darlene
- Gualberto Cláudia G.
- Guedes Marcelino Carneiro
- Guedes Matheus L.
- Guedes Matheus L.
- Guerrero Jesús Enrique Burgos
- Guilherme Edson
- Guimaraes Aretha Franklin
- Guimarães David Pedroza
- Görgens Eric Bastos
- Hamada Neusa
- Haugaasen Torbjørn
- Hawes Joseph E.
- Hercos Alexandre
- Hilário Renato Richard
- Holanda de Andrade André Luiz Ramos
- Holmgren Milena
- Householder Ethan
- Irume Mariana Victória
- Isaac Victoria
- Isaac Victoria
- Ivanauskas Natalia Macedo
- Izzo Thiago Junqueira
- Jakovac Catarina C.
- Jardim Gabriela Abrantes
- Juen Leandro
- Juen Leandro
- Junqueira André Braga
- Korasaki Vanesca
- Koroiva Ricardo
- Krolow Tiago Kütter
- Kunz Sustanis Horn
- Landeiro Victor Lemes
- Lanna João
- Laranjeiras Thiago Orsi
- Lasky Jesse R.
- Lasmar Chaim
- Laurance Susan
- Laurance William
- Leal Cecilia G.
- Leal Cecilia G.
- Lees Alexander C.
- Lees Alexander C.
- Leitão Rafael Pereira
- Levis Carolina
- Leão Híngara
- Ligeiro Raphael
- Lima Gisiane Rodrigues
- Lima Jônatas
- Lima Ysadhora Gomes de
- Lobato Cleonice Maria Cardoso
- Lopes Aline
- Lopes Maria Aparecida
- Lourenço Luzia da Silva
- Louzada Julio
- Luize Bruno Garcia
- Luther David
- Machado Tatiana Lemos da Silva
- Maciel Rafaella
- Maciel Rafaella
- Magalhães José Leonardo Lima
- Magnusson William E.
- Mahood Simon
- Maia Laís Ferreira
- Maldaner Maria Eduarda
- Malhi Yadvinder
- Manzatto Angelo Gilberto
- Maracahipes Leandro
- Maracahipes-Santos Leonardo
- Mariano Rodolfo
- Marimon Beatriz S.
- Marimon-Junior Ben Hur
- Marques Elineide E.
- Marsh Charles J.
- Martins Maria Pires
- Martins Mila Ferraz de Oliveira
- Martins Renato Tavares
- Massam Mike R.
- Matavelli Rodrigo
- Maximiano Marina Franco de Almeida
- Mazzei Lucas
- Medeiros Herison
- Medeiros Marcelo Brilhante de
- Medeiros Natália
- Melgaço Karina
- Melinski Ramiro Dário
- Melo Lima Diego Viana
- Melo Antonio Willian Flores de
- Melo Bruna Santos Bitencourt de
- Melo Gracilene da Costa de
- Mendes Aguiar Jonas José
- Mendes Keila Rêgo
- Mendes Raimundo N.G.
- Mendes Thiago Pereira
- Mendonça Fernando P.
- Menezes Andressa Silvana Oliveira de
- Mestre Luiz A.M.
- Metcalf Oliver Charles
- Michelan Thaisa Sala
- Miguel Thiago Barros
- Milheiras Sérgio
- Milliken William
- Miranda Ires Paula de Andrade
- Miranda Patrícia Nakayama
- Montag Luciano Fogaça de Assis
- Monteiro Jr. Cláudio da Silva
- Monteiro Marcília Gabriella Tavares
- Morandi Paulo S.
- Morato Elder Ferreira
- Moreira Felipe F.F.
- Mormul Roger Paulo
- Mortati Amanda Frederico
- Moser Pamela
- Moura Mario R.
- Moura Mario R.
- Muelbert Adriane Esquivel
- Muñoz Gutiérrez Jhonatan Andrés
- Naka Luciano Nicolas
- Nascimento Henrique Eduardo Mendonça
- Nascimento Marcelo Trindade
- Nascimento Rodrigo O.
- Nascimento Rodrigo O.
- Navarro Paolucci Lucas
- Nelson Bruce
- Nessimian Jorge Luiz
- Neto Francisco Valente-
- Nichols Elizabeth
- Nienow Samuel
- Nogueira Denis Silva
- Nonato Flávia Alessandra da Silva
- Noriega Jorge Ari
- Noronha Janaína Costa
- Novo Evlyn Márcia Moraes de Leão
- Nunes Cassio A.
- Nunes Cassio A.
- Nunes Luis Gabriel de Oliveira
- o Santos Marcos Pérsi Dantas
- Obermuller Flávio Amorim
- Oliveira Pes Ana Maria
- Oliveira Alexandre Adalardo de
- Oliveira Amanda Batista da Silva de
- Oliveira Cinthia Pereira de
- Oliveira Edmar Almeida de
- Oliveira Fabiana Ferreira de
- Oliveira José Max B.
- Oliveira Marco Antonio de
- Oliveira Marcus Vinicio Neves D.
- Oliveira Rodrigo Leonardo Costa de
- Oliveira Sérgio Augusto Vidal de
- Oliveira Victor Hugo Fonseca
- Oliveira Vívian Campos de
- Oliveira Washington Luis de
- Olivo Neto Antonio Miguel
- Pansonato Marcelo Petratti
- Passos Maria Inês S.
- Paula William Sousa de
- Pauletto Daniela
- Pedroza Diego
- Peixoto Ualerson
- Penagos Cristian Camilo Mendoza
- Perdiz Ricardo de Oliveira
- Pereira Jorge Luiz da Silva
- Peres Carlos A.
- Peruquetti Patricia Santos Ferreira
- Phillips Oliver L.
- Phillips Oliver L.
- Piedade Alexandra Rocha da
- Piedade Maria Teresa Fernandez
- Pombo Maihyra Marina
- Pompeu Paulo dos Santos
- Pontes-Lopes Aline
- Pozzobom Ully Mattilde
- Prado Livia Pires do
- Prance Ghillean T.
- Pringle Elizabeth G.
- Prist Paula
- Prudente Bruno da Silveira
- Puker Anderson
- Pérez-Mayorga María Angélica
- Quaresma Adriano
- Queiroz Antonio C.M.
- Queiroz Helder Lima de
- r Costa Neto Salustiano Vila da
- Raseira Marcelo Bassols
- Rechetelo Juliana
- Reis Fagno
- Reis Leonardo Pequeno
- Resende Angelica F.
- Resende Angelica F.
- Revilla Juan David Cardenas
- Ribas Carla Rodrigues
- Ribeiro José Moacir Ferreira
- Ribeiro Rodrigo Arison Barbosa
- Ribeiro Sabina Cerruto
- Ribeiro Sérvio Pontes
- Ribeiro Vanessa Soares
- Rodrigues Domingos de Jesus
- Rodrigues Silvia Barbosa
- Rodrigues Taís Helena Araujo
- Roque Fabio de Oliveira
- Rosa Dian Carlos Pinheiro
- Rosalino L. M.
- Rousseau Guillaume Xavier
- Ruschel Ademir
- Rutt Cameron L.
- s de Lima Robson Borge
- Salcedo Ana Karina Moreyra
- Sales Francisco Matheus da Silva
- Salles Frederico Falcão
- Salomão Rafael P.
- Salomão Renato Portela
- Santana Edrielly Carolinne Carvalho de
- Santana Flávia Delgado
- Santiago Wagner Tadeu Vieira
- Santos Ferreira Victor Rennan
- Santos Neto Cláudio Rabelo dos
- Santos Allan Paulo Moreira dos
- Santos Bruno Borges
- Santos Cleverson Rannieri Meira dos
- Santos Cássia Anicá dos
- Santos Deane Cabral dos
- Santos Ednaira Alencar dos
- Santos Isis Caroline Siqueira
- Santos Jean Carlos
- Santos Talitha Ferreira dos
- Sarmento Priscila S. de M.
- Schietti Juliana
- Schietti Juliana
- Schmidt Fernando Augusto
- Schmidt Fernando Augusto
- Schwartz Gustavo
- Schöngart Jochen
- Scudeller Veridiana Vizoni
- Shimabukuro Yosio Edemir
- Shimano Yulie
- Shutt Jack
- Shutt Jack
- Silva Brito Joás
- Silva Camila V.J.
- Silva Celice Alexandre
- Silva Dennis Rodrigues da
- Silva Diego Armando Silva da
- Silva Fernando Augusto Barbosa
- Silva José Orlando de Almeida
- Silva Otávio Guilherme Morais da
- Silva Ricardo José da
- Silva Richarlly da Costa
- Silva Robson dos Santos Alves da
- Silva Sonaira Souza da
- Silva Thiago Sanna Freire
- Silva Victória de Nazaré Gama
- Silva Wegliane Campelo da
- Silva Wheriton Fernando Moreira da
- Silvano Renato Azevedo Matias
- Silveira Juliana M.
- Silveira Juliana M.
- Silveira Luis Fábio
- Silveira Marcos
- Silveira Maria Aurea Pinheiro de Almeida
- Silvério Divino V.
- Simon Marcelo Fragomeni
- Siqueira Emely Laiara Silva de
- Solar Ricardo
- Sousa Sidney Araújo de
- Sousa Thaiane
- Souto Paula
- Souza Flávia Kelly Siqueira de
- Souza Jorge Luiz Pereira de
- Souza Mateus Fernando de
- Souza Márcia Regina de
- Souza Priscila
- Stegmann Lis
- Stegmann Lis
- Storck-Tonon Danielle
- Stropp Juliana
- Targhetta Natalia
- ter Steege Hans
- ter Steege Hans
- Todeschini Felipe
- Triana Stefania Pinzón
- Uehara-Prado Marcio
- van den Berg Eduardo
- Vasconcelos Heraldo L.
- Vaz-de-Mello Fernando
- Vaz-de-Mello Fernando
- Vedovato Laura Barbosa
- Venticinque Eduardo M.
- Venticinque Eduardo M.
- Veras Daniel Silas
- Vicente Ricardo Eduardo
- Vicentini Alberto
- Vidal Edson
- Vieira Daniel Luis Mascia
- Vieira Ima Célia Guimarães
- Vieira Ima Célia Guimarães
- Vieira Lisandro
- Vieira Simone Aparecida
- Villa Boris
- Vital Marcos José Salgado
- Vulinec Kevina
- Wilker Icaro
- Williamson Bruce
- Wittmann Florian
- Wolfe Jared
- Yamamoto Kedma Cristine
- Zanetti Ronald
- Zanzini Antonio Carlos da Silva
- Zanzini Lucas Pereira
- Zuanon Jansen
- Zuanon Jansen
- Publication venue
- Cell Press
- Publication date
- 01/08/2023
- Field of study
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In
the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio
Pervasive gaps in Amazonian ecological research
- Author
- Aguiar Daniel Praia Portela de
- Aguiar Hilton Jeferson Alves Cardoso de
- Albernaz Ana Luisa
- Albuquerque Bianca Weiss
- Aleixo Alexandre
- Alencar Luana
- Almeida Daniely da Frota
- Almeida Marllus Rafael Negreiros
- Almeida Morgana
- Almeida Rony Peterson Santos
- Almeida Wanessa Rejane de
- Alvarado Swanni T.
- Alverga Paula Palhares de Polari
- Alves da Rosa Clarissa
- Alves-Martins Fernanda
- Amado Lílian Lund
- Amaral Dário Dantas do
- Anacléto Maria José Pinheiro
- Andrade Ana Luiza
- Andrade Rafael Barreto de
- Andrade-Silva Joudellys
- Andresen Ellen
- Andretti Christian Borges
- Andriolo Aline
- André Thiago
- Anjos Diego V.
- Aragão Luiz
- Arantes Caroline C.
- Arenas Edith Rosario Clemente
- Arrolho Solange
- Arruda Filipe Viegas de
- Assis Rafael Leandro de
- Azara Ludson
- Azevêdo Carlos Augusto Silva de
- Baccaro Fabricio B.
- Baider Cláudia
- Baker Timothy R.
- Barbosa Edelcilio Marques
- Barbosa Julianna Freires
- Barbosa Reinaldo Imbrozio
- Barbosa Thiago Augusto Pedroso
- Barlow Jos
- Barni Paulo Eduardo
- Barros Gabriel Gazzana
- Barroso Jorcely G.
- Barthem Ronaldo
- Bastos Douglas
- Bastos Rafael Costa
- Batista Anderson Pedro Bernadina
- Begot Tiago Octavio
- Beiroz Wallace
- Benetti Cesar João
- Benone Naraiana Loureiro
- Bentos Tony Vizcarra
- Berenguer Erika
- Bispo Pitágoras C.
- Boldrini Rafael
- Bonates Luiz Carlos de Matos
- Borba Gabriel Costa
- Borges Augusto
- Borges Luiz Henrique Medeiros
- Borges Sérgio Henrique
- Braga Danielle de Lima
- Braga Rafael Benzi
- Brando Paulo
- Brasil Leandro Schlemmer
- Brejão Gabriel Lourenço
- Brito Maiara Tábatha da Silva
- Brito Thaline de Freitas
- Brocardo Carlos Rodrigo
- Brown Irving Foster
- Brulinger Luciane Ferreira Barbosa
- Bueno Anderson S.
- Cabeceira Fernando Gonçalves
- Cabette Helena Soares Ramos
- Cabral Guilherme Sampaio
- Cajaiba Reinaldo Lucas
- Callisto Marcos
- Calor Adolfo Ricardo
- Calvão Lenize Batista
- Camargo José Luís
- Camargo Plínio Barbosa de
- Campana Débora Rodrigues de Souza
- Campos Nubia
- Campos-Filho Eduardo Malta
- Cardoso Maira Rodrigues
- Carim Marcelo de Jesus Veiga
- Carmo Guilherme Henrique Pompiano do
- Carniello Maria Antonia
- Carpanedo Rainiellen de Sá
- Carreiras João
- Carvalho Fernanda Antunes
- Carvalho Fernando Geraldo
- Carvalho Fernando Rogério de
- Carvalho Karine Santana
- Carvalho Lidiany Camila da Silva
- Carvalho Lucélia Nobre
- Carvalho Raquel L.
- Casadei-Ferreira Alexandre
- Casatti Lílian
- Castello Leandro
- Castilho Carolina
- Castro Arlison Bezerra
- Castro Flávio Siqueira de
- Castro Wendeson
- Catarino Michel
- Cavalheiro Larissa
- Cerqueira Silva Július César
- Cerqueira Pablo Vieira
- Cintra Bruno B.L.
- Cochrane Mark A.
- Coelho de Souza Fernanda
- Coelho Luiz de Souza
- Coletti Fabrício
- Cordeiro Carlos Leandro
- Cornelius Cintia
- Correa Anne Sthephane A.S.
- Costa Batista Michela
- Costa Daniel da Silva
- Costa Flavia R.C.
- Costa Janaina Barbosa Pedrosa
- Costa Jessica Gomes
- Costa Maria Katiane Sousa
- Costa Marília Maria Silva da
- Couceiro Sheyla Regina Marques
- Cravo Jessica Soares
- Crema Luciana Carvalho
- Cruz Paulo Vilela
- Cruz Wesley Jonatar Alves da
- Cunha Erlane José Rodrigues da
- d'Horta Fernando Mendonça
- da Rocha Maíra
- da Silva Guimarães José Renan
- da Silva Menger Juliana
- da Silva Elidiomar R.
- da Silva Gustavo Cardoso
- da Silva Júlia Santana
- da Silva Karina Dias
- da Silva Letícia Fernandes
- da Silva Márcio Joaquim
- da Silva Pedro Giovâni
- da Silva Rogério Rosa
- Daly Douglas
- Damasco Gabriel
- Davis Bradley
- de Abreu Jadson Coelho
- de Albuquerque Emília Zoppas
- de Brito Janaina Gomes
- de Faria Falcão Jéssica Caroline
- de Lima Alves Adriana
- de Matos Liliane Stedile
- de Oliveira Melo Lia
- de Resende Bethânia Oliveira
- de Sousa Gorayeb Inocêncio
- de Toledo José Julio
- Delabie Jacques Hubert Charles
- Demarchi Layon Oreste
- Desidério Gleison Robson
- Deus Claudia Pereira de
- Dias Murilo S.
- do Vale Julio Daniel
- Domingues Tomas F.
- Doria Carolina Rodrigues da Costa
- dos Anjos Marcelo Rodrigues
- Douglas Danyhelton
- Duarte Ritter Camila
- Dumas Leandro Lourenço
- Durgante Flavia
- Dutra Dhâmyla Bruna de Souza
- Dutra Silvia Leitão
- Dáttilo Wesley
- e Gomes Jerrian Oliveira
- e Pérez Raúl Enriqu Pirela
- Edwards David P.
- Elias Fernando
- Emilio Thaise
- Esposito Maria Cristina
- Espírito Santo Nádia Barbosa
- Espírito-Santo Helder M.V.
- Fadini Rodrigo Ferreira
- Fares Ana Luisa
- Faria Ana Paula Justino
- Farias Emanuelle de Sousa
- Feitosa Rodrigo Machado
- Feitosa Yuri
- Feldpausch Ted R.
- Fernandes Itanna Oliveira
- Fernandes Izaias
- Ferreira Aurélia Bentes
- Ferreira Joice
- Ferreira Leandro Valle
- Ferreira Nelson
- Ferreira-Ferreira Jefferson
- Firmino Viviane
- Flores Bernardo M.
- Florêncio Fernando Prado
- Fontenele Luane
- França Filipe
- França Filipe M.
- Freitas Carlos
- Freitas Madson Antonio Benjamin
- Freitas Marina Guimarães
- Félix Nathalia Silva
- Galuch André V.
- Gama Neto Jaime de Liege
- Gastauer Markus
- Geber Filho Adem Nagibe dos Santos
- Ghidini André Ricardo
- Giacomin Leandro
- Giarrizzo Tommaso
- Giehl Nubia França da Silva
- Godoy Bruno Spacek
- Gomes Vitor Hugo Freitas
- Gontijo Alexandre
- Gonçalves Inês Correa
- Graça Paulo Mauricio de Alencastro
- Griffiths Hannah
- Gris Darlene
- Gualberto Cláudia G.
- Guedes Marcelino Carneiro
- Guedes Matheus L.
- Guerrero Jesús Enrique Burgos
- Guilherme Edson
- Guimaraes Aretha Franklin
- Guimarães David Pedroza
- Görgens Eric Bastos
- Hamada Neusa
- Haugaasen Torbjørn
- Hawes Joseph E.
- Hercos Alexandre
- Hilário Renato Richard
- Holanda de Andrade André Luiz Ramos
- Holmgren Milena
- Householder Ethan
- Irume Mariana Victória
- Isaac Victoria
- Ivanauskas Natalia Macedo
- Izzo Thiago Junqueira
- Jakovac Catarina C.
- Jardim Gabriela Abrantes
- Juen Leandro
- Junqueira André Braga
- Korasaki Vanesca
- Koroiva Ricardo
- Krolow Tiago Kütter
- Kunz Sustanis Horn
- Landeiro Victor Lemes
- Lanna João
- Laranjeiras Thiago Orsi
- Lasky Jesse R.
- Lasmar Chaim
- Laurance Susan
- Laurance William
- Leal Cecilia G.
- Lees Alexander C.
- Leitão Rafael Pereira
- Levis Carolina
- Leão Híngara
- Ligeiro Raphael
- Lima Gisiane Rodrigues
- Lima Jônatas
- Lima Ysadhora Gomes de
- Lobato Cleonice Maria Cardoso
- Lopes Aline
- Lopes Maria Aparecida
- Lourenço Luzia da Silva
- Louzada Julio
- Luize Bruno Garcia
- Luther David
- Machado Tatiana Lemos da Silva
- Maciel Rafaella
- Magalhães José Leonardo Lima
- Magnusson William E.
- Mahood Simon
- Maia Laís Ferreira
- Maldaner Maria Eduarda
- Malhi Yadvinder
- Manzatto Angelo Gilberto
- Maracahipes Leandro
- Maracahipes-Santos Leonardo
- Mariano Rodolfo
- Marimon Beatriz S.
- Marimon-Junior Ben Hur
- Marques Elineide E.
- Marsh Charles J.
- Martins Maria Pires
- Martins Mila Ferraz de Oliveira
- Martins Renato Tavares
- Massam Mike R.
- Matavelli Rodrigo
- Maximiano Marina Franco de Almeida
- Mazzei Lucas
- Medeiros Herison
- Medeiros Marcelo Brilhante de
- Medeiros Natália
- Melgaço Karina
- Melinski Ramiro Dário
- Melo Lima Diego Viana
- Melo Antonio Willian Flores de
- Melo Bruna Santos Bitencourt de
- Melo Gracilene da Costa de
- Mendes Aguiar Jonas José
- Mendes Keila Rêgo
- Mendes Raimundo N.G.
- Mendes Thiago Pereira
- Mendonça Fernando P.
- Menezes Andressa Silvana Oliveira de
- Mestre Luiz A.M.
- Metcalf Oliver Charles
- Michelan Thaisa Sala
- Miguel Thiago Barros
- Milheiras Sérgio
- Milliken William
- Miranda Ires Paula de Andrade
- Miranda Patrícia Nakayama
- Montag Luciano Fogaça de Assis
- Monteiro Cláudio da Silva
- Monteiro Marcília Gabriella Tavares
- Morandi Paulo S.
- Morato Elder Ferreira
- Moreira Felipe F.F.
- Mormul Roger Paulo
- Mortati Amanda Frederico
- Moser Pamela
- Moura Mario R.
- Muelbert Adriane Esquivel
- Muñoz Gutiérrez Jhonatan Andrés
- Naka Luciano Nicolas
- Nascimento Henrique Eduardo Mendonça
- Nascimento Marcelo Trindade
- Nascimento Rodrigo O.
- Navarro Paolucci Lucas
- Nelson Bruce
- Nessimian Jorge Luiz
- Neto Francisco Valente
- Nichols Elizabeth
- Nienow Samuel
- Nogueira Denis Silva
- Nonato Flávia Alessandra da Silva
- Noriega Jorge Ari
- Noronha Janaína Costa
- Novo Evlyn Márcia Moraes de Leão
- Nunes Cassio A.
- Nunes Luis Gabriel de Oliveira
- o Santos Marcos Pérsi Dantas
- Obermuller Flávio Amorim
- Oliveira Pes Ana Maria
- Oliveira Alexandre Adalardo de
- Oliveira Amanda Batista da Silva de
- Oliveira Cinthia Pereira de
- Oliveira Edmar Almeida de
- Oliveira Fabiana Ferreira de
- Oliveira José Max B.
- Oliveira Marco Antonio de
- Oliveira Marcus Vinicio Neves D.
- Oliveira Rodrigo Leonardo Costa de
- Oliveira Sérgio Augusto Vidal de
- Oliveira Victor Hugo Fonseca
- Oliveira Vívian Campos de
- Oliveira Washington Luis de
- Olivo Neto Antonio Miguel
- Pansonato Marcelo Petratti
- Passos Maria Inês S.
- Paula William Sousa de
- Pauletto Daniela
- Pedroza Diego
- Peixoto Ualerson
- Penagos Cristian Camilo Mendoza
- Perdiz Ricardo de Oliveira
- Pereira Jorge Luiz da Silva
- Peres Carlos A.
- Peruquetti Patricia Santos Ferreira
- Phillips Oliver L.
- Piedade Alexandra Rocha da
- Piedade Maria Teresa Fernandez
- Pombo Maihyra Marina
- Pompeu Paulo dos Santos
- Pontes-Lopes Aline
- Pozzobom Ully Mattilde
- Prado Livia Pires do
- Prance Ghillean T.
- Pringle Elizabeth G.
- Prist Paula
- Prudente Bruno da Silveira
- Puker Anderson
- Pérez-Mayorga María Angélica
- Quaresma Adriano
- Queiroz Antonio C.M.
- Queiroz Helder Lima de
- r Costa Neto Salustiano Vila da
- Raseira Marcelo Bassols
- Rechetelo Juliana
- Reis Fagno
- Reis Leonardo Pequeno
- Resende Angelica F.
- Revilla Juan David Cardenas
- Ribas Carla Rodrigues
- Ribeiro José Moacir Ferreira
- Ribeiro Rodrigo Arison Barbosa
- Ribeiro Sabina Cerruto
- Ribeiro Sérvio Pontes
- Ribeiro Vanessa Soares
- Rodrigues Domingos de Jesus
- Rodrigues Silvia Barbosa
- Rodrigues Taís Helena Araujo
- Roque Fabio de Oliveira
- Rosa Dian Carlos Pinheiro
- Rosalino Luís Miguel do Carmo
- Rousseau Guillaume Xavier
- Ruschel Ademir
- Rutt Cameron L.
- s de Lima Robson Borge
- Salcedo Ana Karina Moreyra
- Sales Francisco Matheus da Silva
- Salles Frederico Falcão
- Salomão Rafael P.
- Salomão Renato Portela
- Santana Edrielly Carolinne Carvalho de
- Santana Flávia Delgado
- Santiago Wagner Tadeu Vieira
- Santos Ferreira Victor Rennan
- Santos Neto Cláudio Rabelo dos
- Santos Allan Paulo Moreira dos
- Santos Bruno Borges
- Santos Cleverson Rannieri Meira dos
- Santos Cássia Anicá dos
- Santos Deane Cabral dos
- Santos Ednaira Alencar dos
- Santos Isis Caroline Siqueira
- Santos Jean Carlos
- Santos Talitha Ferreira dos
- Sarmento Priscila S.de M.
- Schietti Juliana
- Schmidt Fernando Augusto
- Schwartz Gustavo
- Schöngart Jochen
- Scudeller Veridiana Vizoni
- Shimabukuro Yosio Edemir
- Shimano Yulie
- Shutt Jack
- Silva Brito Joás
- Silva Camila V.J.
- Silva Celice Alexandre
- Silva Dennis Rodrigues da
- Silva Diego Armando Silva da
- Silva Fernando Augusto Barbosa
- Silva José Orlando de Almeida
- Silva Otávio Guilherme Morais da
- Silva Ricardo José da
- Silva Richarlly da Costa
- Silva Robson dos Santos Alves da
- Silva Sonaira Souza da
- Silva Thiago Sanna Freire
- Silva Victória de Nazaré Gama
- Silva Wegliane Campelo da
- Silva Wheriton Fernando Moreira da
- Silvano Renato Azevedo Matias
- Silveira Juliana M.
- Silveira Luis Fábio
- Silveira Marcos
- Silveira Maria Aurea Pinheiro de Almeida
- Silvério Divino V.
- Simon Marcelo Fragomeni
- Siqueira Emely Laiara Silva de
- Solar Ricardo
- Sousa Sidney Araújo de
- Sousa Thaiane
- Souto Paula
- Souza Flávia Kelly Siqueira de
- Souza Jorge Luiz Pereira de
- Souza Mateus Fernando de
- Souza Márcia Regina de
- Souza Priscila
- Stegmann Lis
- Storck-Tonon Danielle
- Stropp Juliana
- Targhetta Natalia
- ter Steege Hans
- Todeschini Felipe
- Triana Stefania Pinzón
- Uehara-Prado Marcio
- van den Berg Eduardo
- Vasconcelos Heraldo L.
- Vaz-de-Mello Fernando
- Vedovato Laura Barbosa
- Venticinque Eduardo M.
- Veras Daniel Silas
- Vicente Ricardo Eduardo
- Vicentini Alberto
- Vidal Edson
- Vieira Daniel Luis Mascia
- Vieira Ima Célia Guimarães
- Vieira Lisandro
- Vieira Simone Aparecida
- Villa Boris
- Vital Marcos José Salgado
- Vulinec Kevina
- Wilker Icaro
- Williamson Bruce
- Wittmann Florian
- Wolfe Jared
- Yamamoto Kedma Cristine
- Zanetti Ronald
- Zanzini Antonio Carlos da Silva
- Zanzini Lucas Pereira
- Zuanon Jansen
- Publication venue
- Publication date
- 21/08/2023
- Field of study
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost
Ocorrência de Trichopria sp. (Hymenoptera: Diapriidae) atacando pupas de Chrysomya putoria (Wiedemann) Diptera: Calliphoridae) na granja
- Author
- Angelo P. do Prado
- Axtell R.C.
- Berti Filho E.
- Boucek Z.
- Boucek Z.
- Bruno T.V.
- Costa V.A.
- De Santis L
- De Santis L.
- Ebert D.
- Guimarães J.H.
- Guimarães J.H.
- Huggert L.
- Hulley P.E.
- Hulley P.E.
- Kogan M.
- Legner E.F.
- Legner E.F.
- Legner E.F.
- Legner E.F.
- Legner E.F.
- Ludwig J.A.
- Madeira N.G.
- Marisa R. Monteiro
- Merchante M.E.
- Morgan P.B.
- Sereno F.P.S.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Shareholder wealth gains through better corporate governance—The case of European LBO-transactions
- Author
- A. Admati
- A. Agrawal
- A. Shleifer
- André Betzer
- B. Burrough
- B.J. Long De
- C. Loderer
- C. Weir
- C. Weir
- C. Weir
- C.I. Lee
- C.J. Corrado
- Charlie Weir
- Christian Andres
- E.F. Fama
- E.F. Fama
- G.L. Hite
- H. Angelo De
- H. Mehran
- J. Franks
- J. Mcconnell
- J. Tirole
- K. Lehn
- K. Peasnell
- L. Lowenstein
- L. Marais
- L.H.P. Lang
- L.M. Gucht Van Der
- M. Faccio
- M. Jensen
- M. Jensen
- M. Jensen
- M. Jensen
- N.G. Travlos
- P. Halpern
- R. La Porta
- R. Morck
- S. Beiner
- S.J. Brown
- S.J. Grossman
- S.N. Kaplan
- T. Opler
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Cell-Derived Microparticles and Acute Coronary Syndromes: Is there a Predictive Role for Microparticles?
- Author
- Abbas M.
- Antigoni Miliou
- Bekler A.
- Berckmans R.J.
- Berezin A.E.
- Bernal-Mizrachi L.
- Bernal-Mizrachi L.
- Bernard S.
- Biasucci L.M.
- Boulanger C.M.
- Chargaff E.
- Chiva-Blanch G.
- Chiva-Blanch G.
- Christersson C.
- Cimmino G.
- Crea F.
- Curtis A.M.
- Dignat-George F.
- Dimitrios Bertsias
- Dimitris Tousoulis
- Duran M.
- Dymicka-Piekarska V.
- Effimia Zacharia
- Empana J.P.
- Faille D.
- Fan Y.
- Fatih Ozlu,M.
- Gawaz M.
- George M.
- George-Angelo Papamikroulis
- Giannopoulos G.
- Giannopoulos G.
- Gonçalves S.
- Habersberger J.
- Han W.Q.
- Hargett L.A.
- Hartopo A.B.
- Horn P.
- Huisse M.G.
- Huisse M.G.
- Héloire F.
- Ilhan E.
- Jung C.
- Kafian S.
- Karabulut A.
- Katopodis J.N.
- Keuren J.F.
- Konstantinos Zacharias
- Levin G.
- Li M.
- Libby P.
- Libby P.
- Liu M.
- Liu Y.
- Lu Y.
- Lumsden N.G.
- Mackman N
- Mallat Z.
- Maly M.
- Matsumoto N.
- Matsumoto N.
- Mavroudis C.A.
- Michelsen A.E.
- Min P.K.
- Montoro-García S.
- Montoro-García S.
- Morel O.
- Morel O.
- Morel O.
- Morel O.
- Nijiati M.
- Nijiati M.
- Nikolaos Papageorgiou
- Nomura S.
- Porto I.
- Radecke C.E.
- Rautou P.E.
- Sinning J.M.
- Skeppholm M.
- Souza A.C.
- Stepien E.
- Steppich B.A.
- Suades R.
- Suades R.
- Sun C.
- Tsiantoulas D.
- van der Zee P.M.
- Vidal C.
- Wang L.
- Williams M.S.
- Wolf P
- Xie R.
- Ye S.
- Zhang Y.
- Zhou B.
- Zielinska M.
- Zoi Pallantza
- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study
Recent advances of CuAAC click reaction in building cyclic polymer
- Author
- A.J. Boydston
- B. Chen
- B. Laurent
- B. Zhang
- B. Zhang
- B.A. Laurent
- B.M. Rosen
- B.S. Sumerlin
- B.V.K.J. Schmidt
- C.J. Barrett
- C.J. Hawker
- C.J. Hawker
- C.M. Gothard
- C.Z. Zhou
- D. Han
- D. Wang
- D.A. Tomalia
- D.E. Lonsdale
- D.E. Lonsdale
- D.E. Lonsdale
- D.M. Eugene
- E.J. Shin
- F. Zhou
- F. Zhou
- F.A. Leibfarth
- F.P.V. Koch
- G.L. Lu
- G.M. Brooke
- G.M. Brooke
- G.M. Brooke
- G.Y. Shi
- G.Y. Shi
- G.Y. Shi
- G.Y. Shi
- H. Oike
- H.C. Kolb
- H.R. Kricheldorf
- I. Bidd
- J. Chiefari
- J. Jeong
- J. Kulis
- J. Louie
- J. Zhang
- J. Zhao
- J.A. Delaire
- J.B. Williams
- J.C. Barnes
- J.E. Poelma
- J.P. Sadighi
- J.S. Schumm
- K. Matyjaszewski
- K. Matyjaszewski
- K. Takizawa
- K. Takizawa
- K. Zhang
- L. Qin
- M. Igari
- M. Schappacher
- M.A. Cortez
- M.D. Hossain
- N. Hadjichristidis
- N. Sugai
- N. Sugai
- N.G. Angelo
- Nian-chen Zhou
- O. Coulembier
- O.D. Montagnat
- O.I. Paynter
- P. Rochon
- P.H. Rasmussen
- Q. Wang
- R. Chen
- R. Nicolaÿ
- R.B. Merrifield
- R.B. Merrifield
- R.E. Martin
- R.P. Quirk
- S. Binauld
- S. Binauld
- S. Honda
- S. Muthana
- S. Pfeifer
- S. Zhang
- T. Yamamoto
- T.G. Pedersen
- V. Duvigneaud
- V. Percec
- V. Percec
- W. Jeong
- W.M. Gibbons
- Wei Zhang
- X. Fan
- X. He
- X. Jiang
- X. Wan
- X. Zhu
- X.P. Qiu
- Xiu-lin Zhu
- Y. Cai
- Y. Li
- Y. Peng
- Y. Tezuka
- Y. Tezuka
- Y. Tomikawa
- Y. Tomikawa
- Y. Wang
- Y.Q. Dong
- Y.S. Ko
- Yan-yan Zhou
- Ying Li
- Z. Ge
- Z. Ge
- Z. Jia
- Z. Jia
- Z. Lin
- Zheng-biao Zhang
- Zhi-hao Huang
- Zi-mu Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Human Proteinpedia enables sharing of human protein data [4]
- Author
- Ahmed M. (Mukhtar)
- Ahn N.G. (Natalie G.)
- Alexandre H. (Hainard)
- Amanchy R. (Ramars)
- Andrews P.C. (Philip C.)
- Bader J.S. (Joel S.)
- Balgley B.M. (Brian M.)
- Bantscheff M. (Marcus)
- Bennett K.L. (Keiryn L.)
- Björling E. (Erik)
- Blagoev B. (Blagoy)
- Bose R. (Ron)
- Brahmachari S.K. (Samir K.)
- Burlingame A.S. (Alma S.)
- Bustelo X.R. (Xosé R.)
- Cagney G. (Gerard)
- Cantin G.T. (Greg T.)
- Cardasis H.L. (Helene L.)
- Celis J.E. (Julio E.)
- Chaerkady R. (Raghothama)
- Chu F. (Feixia)
- Cole P.A. (Philip A.)
- Costello C.E. (Catherine E.)
- Cotter R.J. (Robert J.)
- Crockett D. (David)
- De Marzo A.M. (Angelo M.)
- DeLany J.P. (James P.)
- DeSouza L.V. (Leroi V.)
- Deutsch E.W. (Eric W.)
- Dransfield E. (Eric)
- Drewes G. (Gerard)
- Droit A. (Arnaud)
- Dunn M.J. (Michael J.)
- Elenitoba-Johnson K. (Kojo)
- Ewing R.M. (Rob M.)
- Eyk J.V. (Jennifer Van)
- Faca V. (Vitor)
- Falkner J. (Jayson)
- Fang X. (Xiangming)
- Fenselau C. (Catherine)
- Figeys D. (Daniel)
- Gagné P. (Pierre)
- Gelfi C. (Cecilia)
- Gevaert K. (Kris)
- Gimble J.M. (Jeffrey M.)
- Gnad F. (Florian)
- Goel R. (Renu)
- Gromov P. (Pavel)
- Hanash S.M. (Samir M.)
- Hancock W.S. (William S.)
- Harsha H.C. (H. C.)
- Hart G. (Gerald)
- Hays F. (Faith)
- He F. (Fuchu)
- Hebbar P. (Prashantha)
- Helsens K. (Kenny)
- Hermeking H. (Heiko)
- Hide W. (Winston)
- Hjernø K. (Karin)
- Hochstrasser D.F. (Denis F.)
- Hofmann O. (Oliver)
- Horn D.M. (David M.)
- Hruban R.H. (Ralph H.)
- Ibarrola N. (Nieves)
- James P. (Peter)
- Jensen O.N. (Ole N.)
- Jensen P.H. (Pia Hønnerup)
- Jung P. (Peter)
- Kandasamy K. (Kumaran)
- Kheterpal I. (Indu)
- Kikuno R.F. (Reiko F.)
- Korf U. (Ulrike)
- Kuster B. (Bernhard)
- Kwon M.-S. (Min-Seok)
- Körner R. (Roman)
- Lee H.-J. (Hyoung-Joo)
- Lee Y.-J. (Young-Jin)
- Lefevre M. (Michael)
- Lehvaslaiho M. (Minna)
- Lescuyer P. (Pierre)
- Levander F. (Fredrik)
- Lim M.S. (Megan S.)
- Loo J.A. (Joseph A.)
- Löbke C. (Christian)
- Mann M. (Matthias)
- Martens L. (Lennart)
- Martinez-Heredia J. (Juan)
- Mathivanan S. (Suresh)
- McComb M. (Mark)
- McRedmond J. (James)
- Mehrle A. (Alexander)
- Menon R. (Rajasree)
- Michael Siu K.W. (K. W.)
- Miller C.A. (Christine A.)
- Mischak H. (Harald)
- Mohan S.S. (S. Sujatha)
- Mohmood R. (Riaz)
- Molina H. (Henrik)
- Moran M.F. (Michael F.)
- Morgan J.D. (James D.)
- Moritz R. (Robert)
- Morzel M. (Martine)
- Muddiman D.C. (David C.)
- Nalli A. (Anuradha)
- Navarro J.D. (J. Daniel)
- Neubert T.A. (Thomas A.)
- Ohara O. (Osamu)
- Oliva R. (Rafael)
- Omenn G.S. (Gilbert S.)
- Oyama M. (Masaaki)
- Paik Y.-K. (Young-Ki)
- Pandey A. (Akhilesh)
- Pennington K. (Kyla)
- Pepperkok R. (Rainer)
- Periaswamy B. (Balamurugan)
- Petricoin E.F. (Emanuel F.)
- Poirier G.G. (Guy G.)
- Prasad T.S.K. (T. S. Keshava)
- Purvine S.O. (Samuel O.)
- Rahiman B.A. (B. Abdul)
- Ramachandra Y.L. (Y. L.)
- Ramachandran P. (Prasanna)
- Rice R.H. (Robert H.)
- Rick J. (Jens)
- Ronnholm R.H. (Ragna H.)
- Salonen J. (Johanna)
- Sanchez J.-C. (Jean-Charles)
- Sayd T. (Thierry)
- Seshi B. (Beerelli)
- Shankari K. (Kripa)
- Sheng S.J. (Shi Jun)
- Shetty V. (Vivekananda)
- Shivakumar K. (K.)
- Simpson R.J. (Richard J.)
- Sirdeshmukh R. (Ravi)
- Smith J. C. (Jeffrey C.)
- Smith R.D. (Richard D.)
- States D.J. (David J.)
- Sugano S. (Sumio)
- Sullivan M. (Matthew)
- Superti-Furga G. (Giulio)
- Takatalo M. (Maarit)
- Thongboonkerd V. (Visith)
- Trinidad J.C. (Jonathan C.)
- Uhlen M. (Mathias)
- Vandekerckhove J. (Joël)
- Vasilescu J. (Julian)
- Veenstra T.D. (Timothy D.)
- Vidal-Taboada J.-M. (José-Manuel)
- Vihinen M. (Mauno)
- Wait R. (Robin)
- Wang X. (Xiaoyue)
- Wiemann S. (Stefan)
- Wu B. (Billy)
- Xu T. (Tao)
- Yates J.R. (John R.)
- Zhong J. (Jun)
- Zhou M. (Ming)
- Zhu Y. (Yunping)
- Zurbig P. (Petra)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2008
- Field of study
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals
- Author
- Abecasis G.R. (Goncalo R.)
- Abecasis G.R. (Goncalo R.)
- Abecasis G.R. (Gonçalo R.)
- Abecasis G.R. (Gonçalo)
- Adair L.S. (Linda)
- Allison M.A. (Matthew)
- Altshuler D. (David)
- Altshuler D. (David)
- Amin N. (Najaf)
- An P. (Ping)
- Ardlie K.G. (Kristin)
- Ardlie K.G. (Kristin)
- Ariyurek Y. (Yavuz)
- Aulchenko Y.S. (Yurii S.)
- Aulchenko Y.S. (Yurii S.)
- Aulchenko Y.S. (Yurii)
- Bacquer O.L. (Olivier)
- Balkau B. (Beverley)
- Balkau B. (Beverley)
- Ballantyne C. (Christie)
- Ballantyne C.M. (Christie M.)
- Ballantyne C.M. (Christie M.)
- Bandinelli S. (Stefania)
- Bandinelli S. (Stefania)
- Barbalic M. (maja)
- Barroso I.
- Barroso I.E. (Inês)
- Barroso I.E. (Inês)
- Barter P. (Phil)
- Beekman M. (Marian)
- Beilby J.P. (John)
- Ben-Shlomo Y.
- Benediktsson R. (Rafn)
- Benediktsson R. (Rafn)
- Bennett A.J. (Amanda)
- Bennett A.J. (Amanda)
- Bergman R.N. (Richard N.)
- Bergman R.N. (Richard N.)
- Bergman R.N. (Richard N.)
- Bergmann S.M. (Sven)
- Bidulescu A. (Aurelian)
- Bis J.C. (Joshua)
- Blagieva R. (Roza)
- Bochud M. (Murielle)
- Boehm B.O. (Bernhard)
- Boehnke M. (Michael)
- Boehnke M. (Michael)
- Boehnke M. (Michael)
- Boekholdt S.M. (Matthijs)
- Boerwinkle E. (Eric)
- Boerwinkle E. (Eric)
- Boerwinkle E.A. (Eric)
- Bonnefond A. (Amélie)
- Bonnycastle L.L. (Lori L.)
- Bonnycastle L.L. (Lori L.)
- Bonnycastle L.L. (Lori)
- Boomsma D.I. (Dorret I)
- Boomsma D.I. (Dorret I.)
- Boomsma D.I. (Dorret)
- Borch-Johnsen K.
- Borecki I.B. (Ingrid B)
- Borja J.B. (Judith)
- Boström K.B. (Kristina Bengtsson)
- Bouatia-Naji N. (Nabila)
- Bravenboer B. (Bert)
- Brunner E. (Eric)
- Buchanan T.A. (Thomas)
- Bumpstead S. (Suzannah)
- Bumpstead S. (Suzannah)
- Burtt N.P. (Noël P.)
- Burtt N.P. (Noël)
- Buxbaum S.G. (Sarah)
- Böhringer S. (Stefan)
- Böttcher Y. (Yvonne)
- Campbell H. (Harry)
- Campbell H. (Harry)
- Campbell H. (Harry)
- Cao A. (Antonio)
- Carlson O.D. (Olga)
- Cauchi S. (Stephane)
- Caulfield M. (Mark)
- Caulfield M.J. (Mark J.)
- Cavalcanti-Proença C. (Christine)
- Chambers J. (John)
- Chambers J.C. (John C.)
- Charpentier G. (Guillaume)
- Charpentier G. (Guillaume)
- Chasman D.I. (Daniel)
- Chen I. (Ida)
- Chen Y.-D.I. (Yii-Der Ida)
- Chen Y.D.I. (Yii-Der Ida)
- Chines P.S. (Peter S.)
- Chines P.S. (Peter)
- Cho Y.S. (Yoon Shin)
- Clarke R. (Robert)
- Coassin S. (Stefan)
- Coin L. (Lachlan)
- Collins F.S. (Francis S.)
- Collins F.S. (Francis S.)
- Collins F.S. (Francis)
- Cooper C. (Charles)
- Cooper C. (Cyrus)
- Cooper M.N. (Matthew)
- Cornelis M. (Marilyn)
- Cornelis M. (Marilyn)
- Couper D.J. (David J.)
- Couper D.J. (David)
- Crawford G. (Gabe)
- Crawford G. (Gabe)
- Crawford G. (Gabriel)
- Crisponi L. (Laura)
- Croteau-Chonka D.C. (Damien)
- Daly M.J. (Mark)
- Dam R.M. (Rob) van
- Dastani Z. (Zari)
- Day I.N.M. (Ian)
- Dedoussis G.V. (George)
- Dehghan A. (Abbas)
- Deloukas P. (Panagiotis)
- Deloukas P. (Panagiotis)
- Delplanque J. (Jerome)
- DIAGRAM+ Consortium
- Dina C. (Christian)
- Dina C. (Christian)
- Dominiczak A. (Anna)
- Dominiczak A.F. (Anna F.)
- Doney A.S.F. (Alex S. F.)
- Doney A.S.F. (Alex)
- Duijn C.M. (Cornelia) van
- Duncan B.B. (Bruce)
- Dupuis J. (Josée)
- Dupuis J. (Josée)
- Dupuis J. (Josée)
- Döring A. (Angela)
- Ebrahim S. (Shanil)
- Egan J.M. (Josephine)
- Egan J.M. (Josephine)
- Ejebe K.G. (Kenechi)
- Elliott A.L. (Amanda)
- Elliott A.L. (Amanda)
- Elliott K.S. (Katherine)
- Elliott P. (Paul)
- Erdmann J. (Jeanette)
- Erdmann J. (Jeanette)
- Erdos M.R. (Michael)
- Erdos M.R. (Michael)
- Evans D.M. (David)
- Faire U. (Ulf) de
- Fedson A.C. (Annette)
- Feitosa M.F. (Mary Furlan)
- Ferreira T. (Teresa)
- Ferrucci L. (Luigi)
- Ferrucci L. (Luigi)
- Fischer-Rosinsky A. (Antje)
- Florez J.C. (Jose C.)
- Florez J.C. (Jose)
- Florez J.C. (Jose)
- Forouhi N.G. (Nita)
- Fouchier S.W. (Sigrid)
- Fox C.S. (Caroline)
- Fox C.S. (Caroline)
- Franklin C.S. (Christopher)
- Franklin C.S. (Christopher)
- Franks P.W. (Paul)
- Frants R. (Rune)
- Frants R.R. (Rune)
- Franzosi M.
- Frayling T.M. (Timothy M.)
- Frayling T.M. (Timothy M.)
- Frayling T.M. (Timothy M.)
- Frayling T.M. (Timothy)
- Froguel P. (Philippe)
- Froguel P. (Philippe)
- Fuchsberger C. (Christian)
- Gabriel S.B. (Stacey)
- Galan P. (Pilar)
- Ganser M. (Martha)
- Garcia M.E. (M.)
- Geus E.J.C. (Eco) de
- Gieger C. (Christian)
- Gieger C. (Christian)
- Gieger C. (Christian)
- Gieger C. (Christian)
- Glazer N.L. (Nicole)
- GLGC Investigators
- Gloyn A.L. (Anna L.)
- Gloyn A.L. (Anna)
- Go M.J. (Min Jin)
- Goel A. (Anuj)
- Gonzalez E. (Elena)
- Goodarzi M. (Mark)
- Graessler J. (Jürgen)
- Grallert H. (Harald)
- Grallert H. (Harald)
- Grarup N. (Niels)
- Grarup N. (Niels)
- Green T. (Todd)
- Greenwood C.M.T. (Celia)
- Griffin S. (Simon)
- Grimsby J. (Jonna)
- Groop L. (Leif)
- Groop L. (Leif)
- Groop L. (Leif)
- Groves C.J. (Christopher)
- Groves C.J. (Christopher)
- Grundy S.M. (Scott)
- Gudnason V. (Vilmundur)
- Guiducci C. (Candace)
- Guiducci C. (Candace)
- Guo X. (Xiuqing)
- Guo X. (Xiuqing)
- Gwilliam R. (Rhian)
- Gyllensten U. (Ulf)
- Gyllensten U. (Ulf)
- Gyllensten U. (Ulf)
- Hadjadj S. (Samy)
- Hadjadj S. (Samy)
- Haeften T.W. (Timon) van
- Hagen K. (Knut)
- Hall A.S. (Alistair)
- Hallmans G. (Göran)
- Hammond N. (Naomi)
- Hamsten A. (Anders)
- Han X. (Xijing)
- Hansen T. (Torben)
- Haritunians T. (Talin)
- Harris T.B. (Tamara B.)
- Harris T.B. (Tamara)
- Hartikainen A.L.
- Hassanali N. (Neelam)
- Hassanali N. (Neelam)
- Hastie N. (Nick)
- Hattersley A.T. (Andrew)
- Haun M. (Margot)
- Havulinna A.S. (Aki)
- Hayward C.
- Hayward C. (Caroline)
- Heath S.C. (Simon)
- Heemst D. (Diana) van
- Hegele R.A. (Robert)
- Heid I.M. (Iris)
- Heid I.M. (Iris)
- Hengstenberg C. (Christian)
- Henneman P. (Peter)
- Henneman P. (Peter)
- Hercberg S. (Serge)
- Herder C. (Christian)
- Herder C. (Christian)
- Herpt T.W. (Thijs) van
- Hicks A.A. (Andrew A.)
- Hicks A.A. (Andrew)
- Hide W.A. (Winston)
- Hillman D.R. (David)
- Hingorani A. (Aroon)
- Hitman G.A. (Graham)
- Hivert M.-F. (Marie-France)
- Hoek M. (Mandy) van
- Hofman A.
- Hofman A. (Albert)
- Hofman A. (Albert)
- Hofman A. (Albert)
- Hofmann O.M. (Oliver)
- Holm H. (Hilma)
- Hottenga J.J. (Jouke Jan)
- Hottenga J.J. (Jouke Jan)
- Hovingh G.K. (Kees)
- Hu F.B. (Frank B)
- Hu F.B. (Frank B.)
- Hu F.B. (Frank)
- Hui J. (Jennie)
- Hung J. (Joe)
- Hunter D.J. (David)
- Huth C. (Cornelia)
- Hveem K. (Kristian)
- Igl W. (Wilmar)
- Illig T. (Thomas)
- Illig T. (Thomas)
- Ingelsson E. (Erik)
- Ingelsson E. (Erik)
- Ingelsson E. (Erik)
- Isaacs A. (Aaron)
- Isaacs A.J. (Aaron)
- Isomaa B. (Bo)
- Isomaa B. (Bo)
- Jackson A.U. (Anne)
- Jackson A.U. (Anne)
- Jarvelin M.-R. (Marjo-Riitta)
- Jarvelin M.-R. (Marjo-Riitta)
- Jarvelin M.-R. (Marjo-Riitta)
- Johansen C.T. (Christopher)
- Johansson A. (Åsa)
- Johnson P.R.V. (Paul R. V.)
- Johnson P.R.V. (Paul)
- Johnson T. (Toby)
- Johnson T. (Toby)
- Johnson T. (Toby)
- Jorgensen T. (Torben)
- Jorgensen T. (Torben)
- Jula A. (Antti)
- Jula A. (Antti)
- Kaakinen M. (Marika)
- Kanaya A. (Alka)
- Kanoni S. (Stavroula)
- Kanoni S. (Stavroula)
- Kao W.H.L. (W. H. Linda)
- Kao W.H.L. (Wen H. L.)
- Kao W.H.L. (Wen)
- Kao W.H.L. (Wen)
- Kaplan L. (Lee)
- Kaprio J. (Jaakko)
- Kapur K. (Karen)
- Karpe F. (Fredrik)
- Kastelein J.J.P. (John)
- Katsareli E. (Efi)
- Kedenko L. (Lyudmyla)
- Kesaniemi Y.A. (Antero)
- Khaw K.-T. (Kay-Tee)
- Khaw K.T.
- Kim Y-J. (Yong-Jin)
- Kim Y.J.
- Kivimaki M. (Mika)
- Kizer J.R. (Jorge)
- Klopp N. (Norman)
- Klopp N. (Norman)
- Kloppenburg M. (Margreet)
- Knight B. (Beatrice)
- Kong A. (Augustine)
- Kong A. (Augustine)
- Kooner J. (Jaspal)
- Koseki M. (Masahiro)
- Koskinen S. (Seppo)
- Kovacs P. (Peter)
- Kraft P. (Peter)
- Kristiansson K. (Kati)
- Kronenberg F. (Florian)
- Kronenberg F. (Florian)
- Kumari M. (Meena)
- Kuusisto J. (Johanna)
- Kuzawa C.W. (Christopher W.)
- Kuzawa C.W. (Christopher)
- Kyvik K.O. (Kirsten O.)
- Kyvik K.O. (Kirsten Ohm)
- Kähönen M. (Mika)
- König I.R. (Inke)
- Laakso M. (Markku)
- Laakso M. (Markku)
- Laakso M. (Markku)
- Laaksonen R. (Reijo)
- Ladouceur M. (Martin)
- Lajunen T. (Taina)
- Lakatta E.G. (Edward G.)
- Lamina C. (Claudia)
- Lamina C. (Claudia)
- Lange L.A. (Leslie)
- Lange L.A. (Leslie)
- Langenberg C. (Claudia)
- Langenberg C. (Claudia)
- Langenberg C. (Claudia)
- Langenberg C. (Claudia)
- Lathrop G. (GMark)
- Launer L.J. (Lenore J.)
- Lauritzen T. (Torsten)
- Lawlor D.A. (Debbie)
- Lecoeur C. (Cécile)
- Lee J.-Y. (Jong-Young)
- Lehtimäki T. (Terho)
- Lettre G. (Guillaume)
- Li M. (Man)
- Li M. (Man)
- Li X. (Xiaohui)
- Li X. (Xiaohui)
- Li Y. (Yun)
- Lieverse A.G. (Aloysius)
- Lindgren C.M. (Cecilia M.)
- Lindgren C.M. (Cecilia)
- Liu C.-T. (Ching-Ti)
- Liu Y. (YongMei)
- Lohman K. (Kurt)
- Lokki M.L.
- Loo B.-M. (Britt-Marie)
- Loos R.J.F. (Ruth)
- Loos R.J.F. (Ruth)
- Loos R.J.F. (Ruth)
- Luan J. (Jian’an)
- Luan J. (Jian’an)
- Luben R.N. (Robert)
- Lucas G. (Gavin)
- Lyssenko V. (Valeriya)
- Lyssenko V. (Valeriya)
- Lyytikäinen L.-P. (Leo-Pekka)
- MAGIC Consortium
- Magnusson P.K. (Patrik)
- Magnusson P.K.E. (Patrik K. E.)
- Mahley R. (Robert)
- Mangino M. (Massimo)
- Mangino M. (Massimo)
- Manning A.K. (Alisa K.)
- Manning A.K. (Alisa)
- Marmot M. (Michael)
- Marre M. (Michel)
- Marroni F. (Fabio)
- Martin N.G. (Nicholas)
- Martinez-Larrad M.T. (Maria Teresa)
- Masson D. (David)
- McArdle W.L. (Wendy)
- McAteer J.B. (Jarred)
- McCarroll S.A. (Steve)
- McCarroll S.A. (Steven)
- McCarthy M.I. (Mark I.)
- McCarthy M.I. (Mark I.)
- McCarthy M.I. (Mark)
- McCulloch L.J. (Laura J.)
- McCulloch L.J. (Laura)
- McPherson R. (Ruth)
- Meigs J.B. (James B.)
- Meigs J.B. (James)
- Meigs J.B. (James)
- Meisinger C. (Christa)
- Meitinger T. (Thomas)
- Meitinger T. (Thomas)
- Meitinger T. (Thomas)
- Melander O. (Olle)
- Melzer D. (David)
- Meneton P. (Pierre)
- Meulenbelt I. (Ingrid)
- Meyre D. (David)
- Midthjell K. (Kristian)
- Mitchell B.D. (Braxton)
- Mohlke K.L. (Karen L.)
- Mohlke K.L. (Karen L.)
- Mohlke K.L. (Karen L.)
- Mohlke K.L. (Karen)
- Mooser V. (Vincent)
- Mooser V. (Vincent)
- Mooser V.E. (Vincent E.)
- Morken M.A. (Mario A.)
- Morken M.A. (Mario)
- Morris A.D. (Andrew D.)
- Morris A.D. (Andrew)
- Morris A.P. (Andrew P.)
- Morris A.P. (Andrew P.)
- Morris A.P. (Andrew)
- Mukherjee S. (Sutapa)
- Munroe P. (Patricia)
- Musani S. (Solomon)
- Musunuru K. (Kiran)
- MuTHER Consortium
- Mägi R. (Reedik)
- Naitza S. (Silvia)
- Narisu N. (Narisu)
- Narisu N. (Narisu)
- Nathan D.M. (David)
- Navarro P. (Pau)
- Navarro P. (Pau)
- Neville M.J. (Matthew)
- Nickerson D.A. (Deborah A.)
- Nickerson D.A. (Deborah)
- Nieminen M.S. (Markku)
- Nilsson P. (Peter)
- Nuotio M.-L. (Marja-Liisa)
- Oostra B.A. (Ben A.)
- Oostra B.A. (Ben)
- Oostra B.A. (Ben)
- Ordovas J.M. (Jose M.)
- Ordovas J.M. (Jose)
- Orho-Melander M. (Marju)
- Orrù M. (Marco)
- Owen K.R. (Katharine)
- O’Connell J. (Jeffrey)
- Pakyz R. (Ruth)
- Palmer C. (Cameron)
- Palmer C.N.A. (Colin N. A.)
- Palmer C.N.A. (Colin)
- Pankow J.S. (James S.)
- Pankow J.S. (James)
- Paolisso G. (Giuseppe)
- Pare G. (Guillame)
- Park T. (Taesung)
- Parker A.N. (Alex)
- Pattaro C. (Cristian)
- Pattaro C. (Cristian)
- Pattou F. (François)
- Paulweber B. (Bernhard)
- Payne F. (Felicity)
- Payne F. (Felicity)
- Pearson D. (Daniel)
- Peden J. (John)
- Pedersen N.L. (Nancy)
- Pedersen O. (Oluf)
- Pedersen O. (Oluf)
- Peloso G.M. (Gina)
- Peltonen L. (Leena Johanna)
- Penninx B.W.J.H.
- Penninx B.W.J.H. (Brenda W. J. H.)
- Penninx B.W.J.H. (Brenda)
- Perola M. (Markus)
- Perola M. (Markus)
- Perola M. (Markus)
- Perry J.R.B. (John R. B.)
- Perry J.R.B. (John R. B.)
- Perry J.R.B. (John)
- Petersen A.K.
- Pfeiffer A.F.H. (Andreas)
- Pichler I. (Irene)
- Pichler I. (Irene)
- Platou C.P. (Carl)
- Polasek O. (Ozren)
- Posthuma D. (Danielle)
- Potter S.C. (Simon)
- Pouta A. (Anneli)
- Pramstaller P.P. (Peter P.)
- Pramstaller P.P. (Peter P.)
- Pramstaller P.P. (Peter Paul)
- Pramstaller P.P. (Peter Paul)
- Proença C. (Christine)
- Prokopenko I. (Inga)
- Prokopenko I. (Inga)
- Province M.A. (Mike)
- Psaty B.M. (Bruce M.)
- Psaty B.M. (Bruce)
- Qi L. (Lu)
- Qi L. (Lu)
- Quertermous T. (Thomas)
- Quertermous T. (Thomas)
- Rader D.J. (Daniel)
- Raitakari O. (Olli)
- Randall J.C. (Joshua)
- Rasmussen-Torvik L.J. (Laura)
- Rathmann W. (Wolfgang)
- Rathmann W. (Wolfgang)
- Raychaudhuri S. (Soumya)
- Rayner N.W. (Nigel W.)
- Rayner N.W. (Nigel William)
- Redline S. (Susan)
- Reilly M.P. (Muredach P.)
- Rice K.M. (Kenneth)
- Richards J.B. (J. Brent)
- Ricketts S.L. (Sally)
- Ridker P.M. (Paul)
- Rieder M. (Mark)
- Rieder M. (Mark)
- Ripatti S. (Samuli)
- Ripatti S. (Samuli)
- Rivadeneira Ramirez F. (Fernando)
- Roberts R. (Robert)
- Robertson N.R. (Neil)
- Roccasecca R.M.
- Rocheleau G. (Ghislain)
- Rocheleau G. (Ghislain)
- Roden M. (Michael)
- Roden M. (Michael)
- Rolandsson O. (Olov)
- Rose L.M. (Lynda)
- Rotter J.I. (Jerome I)
- Rudan I. (Igor)
- Rudan I. (Igor)
- Rudan I. (Igor)
- Ruokonen A. (Aimo)
- Ruokonen A. (Aimo)
- Rybin D. (Denis)
- Sabatti C. (Chiara)
- Saharinen J. (Juha)
- Salomaa V. (Veikko)
- Salomaa V. (Veikko)
- Salomaa V. (Veikko)
- Samani N.J. (Nilesh)
- Samani N.J. (Nilesh)
- Sampson M.J. (Michael J)
- Sampson M.J. (Michael)
- Sandbaek A. (Annelli)
- Sandhu M. (Manjinder)
- Sandhu M.S. (Manjinder)
- Sanna S. (Serena)
- Sanna S. (Serena)
- Sattar N. (Naveed)
- Saxena R. (Richa)
- Saxena R. (Richa)
- Sayer A.A.
- Schadt E.E. (Eric E.)
- Schadt E.E. (Eric)
- Scheet P. (Paul)
- Schlessinger D. (David)
- Schlessinger D. (David)
- Schunkert H. (Heribert)
- Schwarz P.E.H. (Peter)
- Scott L.J. (Laura J.)
- Scott L.J. (Laura)
- Scott R.A. (Robert)
- Scuteri A. (Angelo)
- Scuteri A. (Angelo)
- Scuteri A. (Angelo)
- Seedorf U. (Udo)
- Segrè A.V. (Ayellet)
- Seielstad M. (Mark)
- Semple R.K. (Robert K.)
- Serrano-Ríos M. (Manuel)
- Sethupathy P. (Praveen)
- Sharp S.J. (Stephen)
- Shields B.M. (Beverley)
- Shields B.M. (Beverley)
- Shrader P. (Peter)
- Shrader P. (Peter)
- Shuldiner A.R. (Alan)
- Sigurdsson G. (Gunnar)
- Sigursson G. (Gunnar)
- Sijbrands E. (Eric)
- Sijbrands E.J.G. (Eric J. G.)
- Sijbrands E.J.G. (Eric)
- Silander K. (Kaisa)
- Silander K. (Kaisa)
- Silveira A. (Angela)
- Sim X. (Xueling)
- Sim X. (Xueling)
- Simpson L. (Laila)
- Singleton A. (Andrew)
- Sinisalo J. (Juha)
- Siscovick D.S. (David)
- Siscovick D.S. (David)
- Sladek R. (Rob)
- Sladek R. (Rob)
- Slagboom P.E. (Eline)
- Small K.S. (Kerrin)
- Smith A.V. (Albert Vernon)
- Smith A.V. (Albert)
- Smith A.V. (Davey)
- Smith A.V. (Davey)
- Smith G.D. (George Davey)
- Smith J.D. (Joshua D.)
- Smith N.L. (Nicholas)
- Song K. (Kijoung)
- Soranzo N. (Nicole)
- Soranzo N. (Nicole)
- Sovio U. (Ulla)
- Sparsø T. (Thomas)
- Sparsø T. (Thomas)
- Spector T.D. (Tim D.)
- Spector T.D. (Timothy D.)
- Spector T.D. (Timothy)
- Spranger J. (Joachim)
- St Pourcain B. (Beate)
- Stefansson K. (Kari)
- Stefansson K. (Kari)
- Stein L.D. (Lincoln)
- Steinthorsdottir V. (Valgerdur)
- Steinthorsdottir V. (Valgerdur)
- Strachan D.P. (David)
- Strassburger K. (Klaus)
- Stringham H.M. (Heather M.)
- Stringham H.M. (Heather M.)
- Stringham H.M. (Heather)
- Stumvoll M. (Michael)
- Stylianou I.M. (Ioannis M.)
- Stylianou I.M. (Ioannis)
- Sun Q. (Qi)
- Surakka I. (Ida)
- Swift A.J. (Amy)
- Swift A.J. (Amy)
- Syddall H. (Holly)
- Syvänen A.C.
- Tai E.-S. (E-Shyong)
- Tai E.S. (Shyong)
- Tall A.R. (Alan R.)
- Tanaka T. (Toshiko)
- Taylor H.A. (Herman A.)
- Taylor H.A. (Herman)
- Teslovich T.M. (Tanya M.)
- Teslovich T.M. (Tanya M.)
- Thompson J.R. (John)
- Thompson J.R. (John)
- Thorand B. (Barbara)
- Thorand B. (Barbara)
- Thorleifsson G. (Gudmar)
- Thorleifsson G. (Gudmar)
- Thorleifsson G. (Gudmar)
- Thorsteinsdottir U. (Unnur)
- Thorsteinsdottir U. (Unnur)
- Thorsteinsdottir U. (Unnur)
- Thorsteinsdottir U. (Unnur)
- Tichet J. (Jean)
- Tichet J. (Jean)
- Timpson N.J. (Nicholas J.)
- Timpson N.J. (Nicholas)
- Tracy R.P. (Russell)
- Tuomi T. (Tiinamaija)
- Tuomi T. (Tiinamaija)
- Tuomilehto J. (Jaakko)
- Tuomilehto J. (Jaakko)
- Tuomilehto J. (Jaakko)
- Tönjes A. (Anke)
- Uda M. (Manuela)
- Uda M. (Manuela)
- Uh H.-W. (Hae-Won)
- Uitterlinden A. (Andre)
- Uitterlinden A.G. (Andre G.)
- Uitterlinden A.G. (André)
- Valle T.T. (Timo T.)
- van Duijn C. (Cornelia)
- van Duijn C.M. (Cornelia M.)
- van Duijn C.M. (Cornelia M.)
- van Hoek M. (Mandy)
- Varma D. (Dhiraj)
- Viikari J. (Jorma)
- Visvikis-Siest S. (Sophie)
- Vitart V. (Veronique)
- Vitart V. (Veronique)
- Vliet-Ostaptchouk J.V. (Jana) van
- Vogelzangs N. (Nicole)
- Voight B.F. (Benjamin F.)
- Voight B.F. (Benjamin F.)
- Voight B.F. (Benjamin)
- Vollenweider P. (Peter)
- Vollenweider P. (Peter)
- Vollenweider P. (Peter)
- Waeber G. (Gérard)
- Waeber G. (Gérard)
- Wagner P.J. (Peter)
- Walker M. (Mark)
- Walley A. (Andrew)
- Walters G. (GBragi)
- Walters G.B. (Bragi)
- Ward K.L. (Kim L.)
- Wareham N.J. (Nick J.)
- Wareham N.J. (Nick)
- Wareham N.J. (Nick)
- Watanabe R.M. (Richard M.)
- Watanabe R.M. (Richard)
- Waterworth D. (Dawn)
- Waterworth D. (Dawn)
- Waterworth D.M. (Dawn)
- Watkins H. (Hugh)
- Weedon M.N. (Michael)
- Weedon M.N. (Michael)
- Welch R.P. (Ryan)
- Wheeler E. (Eleanor)
- Whitfield J. (John)
- Wichmann H.-E. (H.-Erich)
- Wichmann H.E. (H. Erich)
- Wichmann H.E. (Heinz Erich)
- Wichmann H.E. (Heinz Erich)
- Wijmenga C. (Cisca)
- Wild S.H. (Sarah)
- Willems van Dijk J.A.P. (Ko)
- Willems S.M. (Sara)
- Willems-vanDijk K. (Ko)
- Willemsen G.
- Willemsen G.A.H.M. (Gonneke)
- Willer C.J. (Cristen J.)
- Willer C.J. (Cristen)
- Williams G.H. (Gordon)
- Wilson J.F. (James F.)
- Wilson J.F. (James)
- Wilson J.G. (James G.)
- Winkler T.W. (Thomas W.)
- Witteman J. (Jacqueline)
- Witteman J.C.M. (Jacqueline C. M.)
- Witteman J.C.M. (Jacqueline)
- Witteman J.C.M. (Jaqueline C. M.)
- Wong T.Y. (Tien Y.)
- Wood A.R. (Andrew)
- Wright A.F. (Alan)
- Wright A.F. (Alan)
- Wu G. (Guanming)
- Wu Y. (Ying)
- Yarnell J.W.G. (John W.)
- Yuan X. (Xin)
- Zabena C. (Carina)
- Zee R.Y.L. (Robert)
- Zeggini E. (Eleftheria)
- Zeggini E. (Eleftheria)
- Zelenika D. (Diana)
- Zethelius B. (Björn)
- Zhai G. (Guangju)
- Zhang W. (Weihua)
- Zhao J.H. (Jing Hua)
- Zhao J.H. (Jing Hua)
- Zhao J.H. (Jing Hua)
- Ziegler A. (Andreas)
- Zillikens M.C. (Carola)
- Zwart J-A. (John-Anker)
- Ódonnell C.J. (Christopher)
- Publication venue
- Publication date
- 01/01/2012
- Field of study
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide association studies in 39,883 individuals of European ancestry to identify genes associated with metabolic disease. We identified 8 novel loci associated with adiponectin levels and confirmed 2 previously reported loci (P = 4.5×10−8- 1.2 ×10−43). Using a novel method to combine data across ethnicities (N = 4,232 African Americans, N = 1,776 Asians, and N = 29,347 Europeans), we identified two additional novel loci. Expression analyses of 436 human adipocyte samples revealed that mRNA levels of 18 genes at candidate regions were associated with adiponectin concentrations after accounting for multiple testing (p<3×10−4). We next developed a multi-SNP genotypic risk score to test the association of adiponectin decreasing risk alleles on metabolic traits and diseases using consortia-level meta-analytic data. This risk score was associated with increased risk of T2D (p = 4.3×10−3, n = 22,044), increased triglycerides (p = 2.6×10−14, n = 93,440), increased waist-to-hip ratio (p = 1.8×10−5, n = 77,167), increased glucose two hours post oral glucose tolerance testing (p = 4.4×10−3, n = 15,234), increased fasting insulin (p = 0.015, n = 48,238), but with lower in HDL- cholesterol concentrations (p = 4.5×10−13, n = 96,748) and decreased BMI (p = 1.4×10−4, n = 121,335). These findings identify novel genetic determinants of adiponectin levels, which, taken together, influence risk of T2D and markers of insulin resistance
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Adamo P. (Pio) d'
- Adan R. (R.)
- Alavere H. (Helene)
- Albrecht E. (Eva)
- Alexander G. (Graeme)
- Alfredsson L. (Lars)
- Amin N. (Najaf)
- Amin N. (Najaf)
- Anderson C.A. (Carl A)
- Ando T. (Tetsuya)
- Ang W.Q. (Wei)
- Antel J. (J.)
- Aspelund T. (T.)
- Aspelund T. (Thor)
- Atalay M. (Mustafa)
- Baker J.H. (Jessica H)
- Barrett J.C. (Jeffrey)
- Barroso I.E. (Inês)
- Beijsterveldt C.E.M. (Toos) van
- Bencko V. (Vladimir)
- Benke K. (K.)
- Berenson G. (Gerald)
- Bergen A.W. (Andrew)
- Bergen N. (N.)
- Bergmann S.M. (Sven)
- Berrettini W. (Wade)
- Berry D. (Diane)
- Bierut L.J. (L. J.)
- Bierut L.J. (Laura)
- Blackburn H. (Hannah)
- Boerwinkle E. (E.)
- Boerwinkle E.A. (Eric)
- Boni C. (Claudette)
- Boomsma D.I. (Dorret)
- Boraska Perica V. (V.)
- Boyd H.A. (H. A.)
- Bradfield J.P. (Jonathan)
- Brandys M. (M.)
- Breen G. (Gerome)
- Breen G. (Gerome)
- Bruson A. (Alice)
- Bulik C.M. (C. M.)
- Burghardt R. (Roland)
- Buring J.E. (Julie)
- Busonero F.
- Busonero F. (F.)
- Byrne E.M. (E. M.)
- Byrne E.M. (Enda)
- Bühren K. (Katharina)
- Carlberg L. (Laura)
- Chanock S.J. (S. J.)
- Chanock S.J. (Stephen)
- Charoen P. (Pimphen)
- Chasman D.I. (Daniel)
- Cichon S. (Sven)
- Clementi M. (Maurizio)
- Cohen-Woods S. (Sarah)
- Coin L. (Lachlan)
- Collier D.A. (David)
- Cone R.D. (Roger D)
- Conlon P. (Peter)
- Conlon P.J. (Peter J)
- Cooper C. (C.)
- Cooper C. (Charles)
- Cornelis M. (Marilyn)
- Corre T. (Tanguy)
- Couper D.J. (David)
- Cousminer D.L. (Diana)
- Coviello A.D. (Andrea)
- Crawford S. (Steve)
- Crisponi L. (Laura)
- Crow S. (Scott)
- Danner U.N. (Unna N)
- Das S. (Shikta)
- Davey Smith G. (G.)
- Davis O.S.P. (Oliver S.)
- de Geus E.J. (E. J.)
- de Kove C. (Carolien)
- De Zwaan M. (M.)
- Dedoussis G.V. (G. V.)
- Dedoussis G.V. (George)
- Degortes D. (Daniela)
- Deloukas P. (Panagiotis)
- Demerath E.W. (E. W.)
- Demerath E.W. (Ellen)
- DeSocio J.E. (Janiece E)
- Dick D.M. (Danielle)
- Dmitrzak-Weglarz M. (Monika)
- Docampo E. (Elisa)
- Dominiczak A. (Anna)
- Dominiczak A. (Anna)
- Duijn C.M. (Cornelia) van
- Duncanson A. (Audrey)
- Döring A. (Angela)
- Econs M.J. (M. J.)
- Econs M.J. (Michael)
- Edkins T. (Ted)
- Egberts K. (Karin)
- Ehrlich S.M. (Stefan)
- Eiriksdottir G. (Gudny)
- Elburg A.A. (Annemarie) van
- Elks C.E. (Cathy)
- Elliott P. (P.)
- Elliott P. (Paul)
- Esko T. (T.)
- Esko T. (Tõnu)
- Espeseth T. (Thomas)
- Estivill X. (Xavier)
- Evans D.M. (D. M.)
- Faire U. (Ulf) de
- Farmer A.E. (Anne E)
- Favaro A. (Angela)
- Feenstra B. (B.)
- Feenstra B. (Bjarke)
- Fernández-Aranda F. (Fernando)
- Ferreli L. (Liana)
- Ferrucci L. (L.)
- Fichter M.M. (M. M.)
- Finan C. (Chris)
- Fischer K. (Krista)
- Flexeder C. (Claudia)
- Floyd J. (Jamie)
- Folsom A.R. (A. R.)
- Folsom A.R. (Aaron)
- Foretova L. (Lenka)
- Foroud T. (T.)
- Foroud T. (Tatiana)
- Forzan M. (Monica)
- Franceschini N. (Nora)
- Frayling T.M. (Timothy)
- Freathy R.M. (Rachel)
- Furth E.F. (Eric) van
- Föcker M. (M.)
- Gaborieau V. (Valerie)
- Gaillard R. (R.)
- Gambaro G. (Giovanni)
- Garcia M.E. (M.)
- Gasparini P. (P.)
- Gasparini P. (Paolo)
- Geller F. (Frank)
- Geus E.J.C. (Eco) de
- Gieger C. (Christian)
- Giegling I. (Ina)
- Gillman M.W. (Matthew W.)
- Goh L.K. (L. K.)
- Gonidakis F. (Fragiskos)
- Gorwood P. (Philip)
- Grant S.F.A. (S. F.A.)
- Grant S.F.A. (Struan)
- Gratacos M. (Monica)
- Gray E. (Emma)
- Groen-Blokhuis M. (Maria)
- Gudbjartsson D.F. (Daniel)
- Gudnason V. (V.)
- Guo Y. (Yongli)
- Guxens Junyent M. (Mònica)
- Hadley D. (D.)
- Hagen K. (Knut)
- Hakonarson H. (Hakon)
- Halmi K.A. (K. A.)
- Hankinson S.E. (S. E.)
- Harris T.B. (Tamara)
- Hattersley A.T. (Andrew)
- Hauser J. (J.)
- Haworth C.M.A. (Claire M.)
- Hayward C. (Caroline)
- He C. (C.)
- Hebebrand J. (J.)
- Heid I.M. (Iris)
- Heinrich J. (J.)
- Helder S. (Sietske)
- Hendriks J. (Judith)
- Herms S. (Stefan)
- Hernandez D.G. (Dena)
- Herpertz-Dahlmann B. (B.)
- Herzog W. (W.)
- Hilliard C.E. (Christopher E)
- Hinney A. (Anke)
- Hirschhorn J.N. (Joel)
- Hocher B. (Berthold)
- Hofman A. (Albert)
- Holloway J.W. (J. W.)
- Holst J.J.
- Horikoshi M. (Momoko)
- Hottenga J.J. (Jouke Jan)
- Hu F.B. (F. B.)
- Huckins L.M. (Laura M)
- Hudson J.I. (James I)
- Huemer J. (Julia)
- Huikari V. (Ville)
- Hunt S.E. (Sarah E)
- Hypponen E. (E.)
- Hypponen E. (Elina)
- Iezebrink K. (Kirsty)
- Illig T. (T.)
- Imgart H. (Hartmut)
- Ingelsson E. (Erik)
- Inoko H. (Hidetoshi)
- Iñiguez C. (C.)
- Jaddoe V.W. (V. W.)
- Jaddoe V.W.V. (Vincent)
- Jall S. (S.)
- Janout V. (Vladimir)
- Jarvelin M.-R. (Marjo-Riitta)
- Jarvelin M.R. (M. R.)
- Jiménez-Murcia G.E.S. (Geòrgia Escaramí Susana)
- Johnson A.D. (Andrew)
- Julia A. (Antonio)
- Kaakinen M. (M.)
- Kalsi G. (Gursharan)
- Kaplan A.S. (Allan S)
- Kaprio J. (Jaakko)
- Kaprio J. (Jaakko)
- Karasik D. (David)
- Karhunen L. (Leila)
- Karwautz A. (Andreas)
- Kas M.J.H. (Martien)
- Keel P. (Pamela)
- Kennedy J.L.
- Keski-Rahkonen A. (Anna)
- Kesselmeier M. (M.)
- Khaw K.T. (K. T.)
- Kiel D.P. (Douglas P.)
- Kilpeläinen T.O. (Tuomas)
- Klump K.L. (K. L.)
- Knudsen G.P.S. (Gun Peggy S.)
- Koeleman B.P.C. (Bobby P. C.)
- Koeleman B.P.C. (Bobby)
- Kolcic I. (Ivana)
- Koller D.L. (Daniel)
- Komaki G. (Gen)
- Koubek D. (Doris)
- Kowgier M. (Matthew)
- Kraft P. (Peter)
- Kutalik Z. (Zoltán)
- La Via M. (Maria)
- Lakka T.A. (Timo)
- Lange L.A. (Leslie)
- Langford C. (Cordelia)
- Launer L.J. (Lenore)
- Laven J.S. (J. S.)
- Lawlor D.A. (D. A.)
- Lawlor D.A. (Debbie)
- Le Hellard S. (Stephanie)
- Lehtimäki T. (Terho)
- Levitan R.D. (Robert D)
- Levy D. (D.)
- Lewin A. (Alex)
- Lewis C.M. (Cathryn)
- Li D. (Dong)
- Li S. (S.)
- Lichtenstein P. (Paul)
- Lilenfeld L. (Lisa)
- Lin P. (P.)
- Lindi V. (Virpi)
- Lissowska J. (Jolanta)
- Liu J. (J.)
- Logan D.W. (Darren W)
- Loos R.J.F. (Ruth)
- Lord G. (Graham)
- Lundervold A.J. (Astri)
- Lunetta K.L. (Kathryn)
- Maggi R. (Reedik)
- Magistretti P. (Pierre)
- Magnusson P.K. (Patrik)
- Maj M. (Mario)
- Mangino M. (Massimo)
- Marsal S. (Sara)
- Marsal S. (Sara)
- Martaskova D. (Debora)
- Martin N.G. (N. G.)
- Mattingsdal M. (Morten)
- Mattingsdal M. (Morten)
- Maxwell A.P. (A.)
- McArdle P.F. (P. F.)
- McCarthy M.I. (M. I.)
- McGinnis R. (Ralph)
- Mcguffin P. (Peter)
- Melbye M. (Mads)
- Merl E. (Elisabeth)
- Metspalu A. (Andres)
- Meulenbelt I. (Ingrid)
- Meurs J.B.J. (Joyce) van
- Middeldorp C.M. (Christel)
- Millwood I.Y. (Iona)
- Mitchell J. (James)
- Mohlke K.L. (Karen)
- Monteleone P. (Palmiero)
- Montgomery G.W. (G. W.)
- Mook-Kanamori D.O. (D. O.)
- Murabito J. (Joanne)
- Murray J.C. (Jeffrey)
- Männik K. (Katrin)
- Müller T.D.
- Nalls M.A. (Michael)
- Navarro P. (Pau)
- Navratilova M. (Marie)
- Nelis M. (M.)
- Nengut S.-G. (Suna-Gumuscu)
- Ness A.R. (A. R.)
- Ness A.R. (Andrew)
- Nivard M. (Michel)
- Nohr C. (Christian)
- Ntalla I. (Ioanna)
- O'Reilly P.F. (P. F.)
- Oken E. (Emily)
- Ong K.K. (K. K.)
- Oostra B.A. (Ben)
- Ophoff R.A. (Roel)
- Ouwehand W.H. (Willem)
- O’Toole J.K. (Julie K)
- Padyukov L. (L.)
- Padyukov L. (Leonid)
- Palmer C. (Cameron)
- Palotie A. (A.)
- Palotie A. (Aarno)
- Panoutsopoulou K. (K.)
- Pantel J. (Jacques)
- Papezova H. (Hana)
- Pararajasingham J. (Jennifer)
- Pare G. (Guillame)
- Parker A.N. (Alex)
- Peacock M. (M.)
- Peacock M. (Munro)
- Pearson E.R. (E. R.)
- Pedersen N.L. (Nancy)
- Peltonen L. (Leena Johanna)
- Pennell C.E. (Craig)
- Perry J.R. (J. R.)
- Pinto D. (Dalila)
- Pinto D. (Duane)
- Plump A.S. (A. S.)
- Polasek O. (Ozren)
- Porcu E. (Eleonora)
- Potter S.C. (Simon)
- Power C. (Christopher)
- Price T.S. (Thomas)
- Prokopenko I. (Inga)
- Rabionet R. (Raquel)
- Raevuori-Helkamaa A. (Anu)
- Rafnar T. (Thorunn)
- Raitakari O.T. (O. T.)
- Rajewski A. (Andrzej)
- Ramoz N. (Nicolas)
- Rayner N.W. (Nigel William)
- Reinvang I. (Ivar)
- Rice J.P. (John)
- Rich S.S. (Stephen)
- Ridker P.M. (Paul)
- Ring S.M. (Susan)
- Ripatti S. (Samuli)
- Ritchie G.R.S. (Graham R.S.)
- Rivadeneira Ramirez F. (Fernando)
- Rivadeneira F. (F.)
- Roberts M. (Marion)
- Rodriguez A. (A.)
- Rotondo A. (Alessandro)
- Rujescu D. (Dan)
- Rybakowski F. (Filip)
- Sala C. (Cinzia)
- Salem R.M. (Rany)
- Salomaa V. (Veikko)
- Sambrook J. (Jennifer)
- Sandford R. (Richard)
- Sanna S. (Serena)
- Santonastaso P. (Paolo)
- Saw S.M. (S. M.)
- Scherag A. (A.)
- Scherag A. (Andre)
- Scherer S.W. (Stephen W)
- Scherer S.W. (Stephen)
- Schlessinger D. (D.)
- Schmidt U. (Ulrike)
- Schosser A. (Alexandra)
- Schreiber S. (Stefan)
- Scuteri A. (A.)
- Scuteri A. (Angelo)
- Sebert S. (S.)
- Segrè A.V. (Ayellet)
- Sheerin N. (Neil)
- Siitonen N. (Niina)
- Simpkin D. (Douglas)
- Slachtova L. (Lenka)
- Sladek R. (Rob)
- Slagboom P.E. (Eline)
- Slof-Op’t Landt M.C.T. (Margarita C. T.)
- Slopien A. (Agnieszka)
- Smith A.V. (Albert)
- Smith A.V. (Davey)
- Smith A.V. (Davey)
- Soranzo N. (Nicole)
- Soranzo N. (Nicole)
- Southam L. (Lorraine)
- Sovio U. (Ulla)
- Spector T.D. (Timothy)
- Srinivasan S.R. (Sathanur)
- Steen V.M. (Vidar)
- Stephens J. (Jonathan)
- Stolk L. (Lisette)
- Strachan D.P. (David)
- Streeten E.A. (Elizabeth)
- Strengman E. (Eric)
- Strober M. (Michael)
- Sulem P. (Patrick)
- Sullivan P.F. (Patrick)
- Sunyer J. (J.)
- Sunyer J. (Jordi)
- Szatkiewicz J.P. (Jin P)
- Szeszenia-Dabrowska N. (Neonila)
- Sørensen T.I.A. (Thorkild)
- Taal H.R. (Rob)
- Tachmazidou I. (Ioanna)
- Taico C. (Chrysecolla)
- Tammesoo M.L. (M. L.)
- Tenconi E. (Elena)
- Teo Y.Y. (Y. Y.)
- Teo Y.Y. (Yik Ying)
- Thiering E. (Elisabeth)
- Thornton L.M. (Laura)
- Thorsteinsdottir U. (Unnur)
- Tiesler C. (C.)
- Tikkanen E. (Emmi)
- Timpson N.J. (Nicholas)
- Toniolo D. (Daniela)
- Tortorella A. (Alfonso)
- Tozzi F. (Federica)
- Trace S.E. (Sara E)
- Treasure J. (Janet)
- Tryggvadottir L. (Laufey)
- Tschop M. (Matthias)
- Tschöp M.H. (M. H.)
- Tsitsika A. (Artemis)
- Tsitsika A. (Artemis)
- Tyrer J. (J.)
- Tziouvas K. (Konstantinos)
- Uda M. (M.)
- Uitterlinden A.G. (André)
- Ulivi S. (Shelia)
- Valcárcel B. (Beatriz)
- van Dam R.M. (R. M.)
- Vannberg F.O. (Frederik O)
- Versini A. (Audrey)
- Visser J.A. (Jenny)
- Volckmar A.-L. (A. L.)
- Vollenweider P. (Peter)
- Waeber G. (Gérard)
- Wagner G. (Gudrun)
- Wareham N.J. (Nick)
- Warrington M. (M.)
- Warrington N.M. (Nicole)
- Waterworth D. (Dawn)
- Weedon M.N. (Michael)
- White S.J. (Stefan)
- Whittaker P. (Pamela)
- Wichmann H.E. (Heinz Erich)
- Widen E.
- Widen E. (E.)
- Willemsen G.A.H.M. (Gonneke)
- Wilson J.F. (J. F.)
- Wingerden S. (Sophie) van
- Winkler T.W. (Thomas W.)
- Woodside D.B. (D Blake)
- Wright A.F. (Alan)
- Yaghootkar H. (H.)
- Yilmaz Z. (Zeynep)
- Young L. (L.)
- Zeggini E. (Eleftheria)
- Zerwas S. (Stephanie)
- Zgaga L. (L.)
- Zhai G. (G.)
- Zhao J.H. (J. H.)
- Zhuang W.V. (W. V.)
- Zipfel S. (S.)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2017
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 × 10-5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 × 10-06/Pfemales: 3.45 × 10-07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation