Pseudo Goldstone Bosons Phenomenology in Minimal Walking Technicolor

We construct the non-linear realized Lagrangian for the Goldstone Bosons associated to the breaking pattern of SU(4) to SO(4). This pattern is expected to occur in any Technicolor extension of the standard model featuring two Dirac fermions transforming according to real representations of the underlying gauge group. We concentrate on the Minimal Walking Technicolor quantum number assignments with respect to the standard model symmetries. We demonstrate that for, any choice of the quantum numbers, consistent with gauge and Witten anomalies the spectrum of the pseudo Goldstone Bosons contains electrically doubly charged states which can be discovered at the Large Hadron Collider.Comment: 25 pages, 5 figure

The effect of hippocampal function, volume and connectivity on posterior cingulate cortex functioning during episodic memory fMRI in mild cognitive impairment

Objectives: Diminished function of the posterior cingulate cortex (PCC) is a typical finding in early Alzheimer’s disease (AD). It is hypothesized that in early stage AD, PCC functioning relates to or reflects hippocampal dysfunction or atrophy. The aim of this study was to examine the relationship between hippocampus function, volume and structural connectivity, and PCC activation during an episodic memory task-related fMRI study in mild cognitive impairment (MCI). Method: MCI patients (n = 27) underwent episodic memory task-related fMRI, 3D-T1w MRI, 2D T2-FLAIR MRI and diffusion tensor imaging. Stepwise linear regression analysis was performed to examine the relationship between PCC activation and hippocampal activation, hippocampal volume and diffusion measures within the cingulum along the hippocampus. Results: We found a significant relationship between PCC and hippocampus activation during successful episodic memory encoding and correct recognition in MCI patients. We found no relationship between the PCC and structural hippocampal predictors. Conclusions: Our results indicate a relationship between PCC and hippocampus activation during episodic memory engagement in MCI. This may suggest that during episodic memory, functional network deterioration is the most important predictor of PCC functioning in MCI. Key Points: • PCC functioning during episodic memory relates to hippocampal functioning in MCI. • PCC functioning during episodic memory does not relate to hippocampal structure in MCI. • Functional network changes are an important predictor of PCC functioning in MCI

The influence of cerebral small vessel disease on default mode network deactivation in mild cognitive impairment

Introduction Cerebral small vessel disease (CSVD) is thought to contribute to cognitive dysfunction in patients with mild cognitive impairment (MCI). The underlying mechanisms, and more specifically, the effects of CSVD on brain functioning in MCI are incompletely understood. The objective of the present study was to examine the effects of CSVD on brain functioning, activation and deactivation, in patients with MCI using task-related functional MRI (fMRI). Methods We included 16 MCI patients with CSVD, 26 MCI patients without CSVD and 25 controls. All participants underwent a physical and neurological examination, neuropsychological testing, structural MRI, and fMRI during a graded working memory paradigm. Results MCI patients with and without CSVD had a similar neuropsychological profile and task performance during fMRI, but differed with respect to underlying (de)activation patterns. MCI patients with CSVD showed impaired deactivation in the precuneus/posterior cingulate cortex, a region known to be involved in the default mode network. In MCI patients without CSVD, brain activation depended on working memory load, as they showed relative 'hyperactivation' during vigilance, and 'hypoactivation' at a high working memory load condition in working memory related brain regions. Conclusions We present evidence that the potential underlying mechanism of CSVD affecting cognition in MCI is through network interference. The observed differences in brain activation and deactivation between MCI patients with and without CSVD, who had a similar 'clinical phenotype', support the view that, in patients with MCI, different types of pathology can contribute to cognitive impairment through different pathways

Concurrent and Reactive Constraint Programming

The Italian Logic Programming community has given several contributions to the theory of Concurrent Constraint Programming. In particular, in the topics of semantics, verification, and timed extensions. In this paper we review the main lines of research and contributions of the community in this fiel

Black Hole Thermodynamics and Statistical Mechanics

We have known for more than thirty years that black holes behave as thermodynamic systems, radiating as black bodies with characteristic temperatures and entropies. This behavior is not only interesting in its own right; it could also, through a statistical mechanical description, cast light on some of the deep problems of quantizing gravity. In these lectures, I review what we currently know about black hole thermodynamics and statistical mechanics, suggest a rather speculative "universal" characterization of the underlying states, and describe some key open questions.Comment: 35 pages, Springer macros; for the Proceedings of the 4th Aegean Summer School on Black Hole

A parameterized unfold/fold transformation framework for definite logic programs

Given a program P, an unfold/fold program transformation system derives a sequence of programs P = P0, P1,:::, Pn, such that Pi+1 is derived from Pi by application of either an unfolding or a folding step. Existing unfold/fold transformation systems for definite logic programs differ from one another mainly in the kind of folding transformations they permit at each step. Some allow folding using a single (possibly recursive) clause while others permit folding using multiple non-recursive clauses. However, none allow folding using multiple recursive clauses that are drawn from some previous program in the transformation sequence. In this paper we develop a parameterized framework for unfold/fold transformations by suitably abstracting and extending the proofs of existing transformation systems. Various existing unfold/fold transformation systems can be obtained by instantiating the parameters of the framework. This framework enables us to not only understand the relative strengths and limitations of these systems but also construct new transformation systems. Specifically we present a more general transformation system that permits folding using multiple recursive clauses that can be drawn from any previous program in the transformation sequence. This new transformation system is also obtained by instantiating our parameterized framework

Affective (self-) transformations: Empathy, neoliberalism and international development

Affective self-transformation premised on empathy has been understood within feminist and anti-racist literatures as central to achieving social justice. Through juxtaposing debates about empathy within feminist and anti-racist theory with rhetorics of empathy in international development, and particularly writing about ‘immersions’, this article explores how the workings of empathy might be reconceptualised when relations of postcoloniality and neoliberalism are placed in the foreground. I argue that in the neoliberal economy in which the international aid apparatus operates, empathetic self-transformation can become commodified in ways that fix unequal affective subjects. Empathy may function here less to produce more intersubjective relations and ways of knowing than it does to augment the moral and affective capacities of development professionals. Yet, I suggest, it is in the ambivalences, tensions and contradictions of both emotion and neoliberalism that spaces for thinking and feeling transnational encounters differently might be cultivated