Current-Voltage Characteristics of Long-Channel Nanobundle Thin-Film Transistors: A Bottom-up Perspective

By generalizing the classical linear response theory of stick percolation to nonlinear regime, we find that the drain current of a Nanobundle Thin Film Transistor (NB-TFT) is described under a rather general set of conditions by a universal scaling formula ID = A/LS g(LS/LC, rho_S * LS * LS) f(VG, VD), where A is a technology-specific constant, g is function of geometrical factors like stick length (LS), channel length (LC), and stick density (rho_S) and f is a function of drain (VD) and gate (VG) biasing conditions. This scaling formula implies that the measurement of full I-V characteristics of a single NB-TFT is sufficient to predict the performance characteristics of any other transistor with arbitrary geometrical parameters and biasing conditions

Thomas-Fermi Method For Particles Obeying Generalized Exclusion Statistics

We use the Thomas-Fermi method to examine the thermodynamics of particles obeying Haldane exclusion statistics. Specifically, we study Calogero-Sutherland particles placed in a given external potential in one dimension. For the case of a simple harmonic potential (constant density of states), we obtain the exact one-particle spatial density and a {\it closed} form for the equation of state at finite temperature, which are both new results. We then solve the problem of particles in a $x^{2/3} ~$ potential (linear density of states) and show that Bose-Einstein condensation does not occur for any statistics other than bosons.Comment: 10 pages (TeX), 2 figures available upon reques

Novel correlations in two dimensions: Some exact solutions

We construct a new many-body Hamiltonian with two- and three-body interactions in two space dimensions and obtain its exact many-body ground state for an arbitrary number of particles. This ground state has a novel pairwise correlation. A class of exact solutions for the excited states is also found. These excited states display an energy spectrum similar to the Calogero-Sutherland model in one dimension. The model reduces to an analog of the well-known trigonometric Sutherland model when projected on to a circular ring.Comment: 8 pages, REVTE

Tree-Level Stability Without Spacetime Fermions: Novel Examples in String Theory

Is perturbative stability intimately tied with the existence of spacetime fermions in string theory in more than two dimensions? Type 0'B string theory in ten-dimensional flat space is a rare example of a non-tachyonic, non-supersymmetric string theory with a purely bosonic closed string spectrum. However, all known type 0' constructions exhibit massless NSNS tadpoles signaling the fact that we are not expanding around a true vacuum of the theory. In this note, we are searching for perturbatively stable examples of type 0' string theory without massless tadpoles in backgrounds with a spatially varying dilaton. We present two examples with this property in non-critical string theories that exhibit four- and six-dimensional Poincare invariance. We discuss the D-branes that can be embedded in this context and the type of gauge theories that can be constructed in this manner. We also comment on the embedding of these non-critical models in critical string theories and their holographic (Little String Theory) interpretation and propose a general conjecture for the role of asymptotic supersymmetry in perturbative string theory.Comment: harvmac, 29 pages; v2 minor changes, version to appear in JHE

Kondo Effect of Quantum Dots in the Quantum Hall Regime

Quantum dots in the quantum Hall regime can have pairs of single Slater determinant states that are degenerate in energy. We argue that these pairs of many body states may give rise to a Kondo effect which can be mapped into an ordinary Kondo effect in a fictitious magnetic field. We report on several properties of this Kondo effect using scaling and numerical renormalization group analysis. We suggest an experiment to investigate this Kondo effect.Comment: To appear in Phys. Rev. B (5 pages, 4 figures); references added; several changes in tex

Novel Phases of Planar Fermionic Systems

We discuss a {\em family} of planar (two-dimensional) systems with the following phase strucure: a Fermi liquid, which goes by a second order transition (with non classical exponent even in mean-field) to an intermediate, inhomogeneous state (with nonstandard ordering momentum) , which in turn goes by a first order transition to a state with canonical order parameter. We analyze two examples: (i) a superconductor in a parallel magnetic field (which was discussed independently by Bulaevskii)for which the inhomogeneous state is obtained for $1.86 T_c \stackrel{\sim}{<} B \stackrel{\sim}{<} 1.86 \sqrt{2} T_c$ where $T_c$ is the critical temperature (in Kelvin) of the superconductor without a field and $B$ is measured in Tesla, and (ii) spinless (or, as is explained, spin polarized) fermions near half-filling where a similar, sizeable window (which grows in size with anisotropy) exists for the intermediate CDW phase at an ordering momentum different from $(\pi , \pi )$. We discuss the experimental conditions for realizing and observing these phases and the Renormalization Group approach to the transitions.Comment: ([email protected],[email protected]) 29 p Latex 4 figs uuencoded separatel

Androgen receptor mutations in prostate cancer

We analyzed the frequency and relevance of mutations in the coding region of the androgen receptor (AR) in genomic DNA extracted from 137 specimens of prostate cancer. The specimens were obtained from the primary tumors of patients affected by stage B disease [15 nonmicrodissected (group 1A) and 84 microdissected (group 1B)] and from the metastatic deposits of individuals with stage D1 disease [8 nonmicrodissected (group 2A) and 30 microdissected (group 2B)] who had not undergone androgen ablation therapy. The study was conducted by PCR-single strand conformational polymorphism (SSCP) analysis of exons 2-8 in the four groups and direct sequence analysis of exon 1 in group 1B. As positive and negative controls, we used genomic DNA extracted from genital skin fibroblasts of patients affected by various forms of androgen resistance with known mutations in the AR. To control for genetic instability, PCR-SSCP analysis of exon 2 of the human progesterone receptor was carried out on each specimen. The overall number of mutations detected was 11 (8%). No mutations were detected in any of the 99 patients with stage B disease. Eleven mutations were detected in exons 2-8 in 8 of the 38 patients with stage D1 disease (all in group 2B). Simultaneous analysis of exon 2 of the progesterone receptor was carried out, and no SSCP changes were identified. These data suggest that AR mutations are rare and presumably do not play a role in the initial phase of prostatic carcinogenesis. The presence of a significant number of AR mutations in metastatic disease indicates that mutations of this molecule may play a role in the most advanced phases of the natural history of this disease, either by facilitating growth or acquisition of the metastatic phenotype

Unified approach to photo and electro-production of mesons with arbitrary spins

A new approach to identify the independent amplitudes along with their partial wave multipole expansions, for photo and electro-production is suggested,which is generally applicable to mesons with arbitrary spin-parity. These amplitudes facilitate direct identification of different resonance contributions.Comment: 11 page

A human carboxypeptidase E/NF-alpha 1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice

Patients with Alzheimer's disease (AD), a common dementia among the aging population, often also suffer from depression. This comorbidity is poorly understood. Although most forms of AD are not genetically inherited, we have identified a new human mutation in the carboxypeptidase E (CPE)/neurotrophic factor-alpha 1 (NF-alpha 1) gene from an AD patient that caused memory deficit and depressive-like behavior in transgenic mice. This mutation consists of three adenosine inserts, introducing nine amino acids, including two glutamines into the mutant protein, herein called CPE-QQ. Expression of CPE-QQ in Neuro2a cells demonstrated that it was not secreted, but accumulated in the endoplasmic reticulum and was subsequently degraded by proteasomes. Expression of CPE-QQ in rat hippocampal neurons resulted in cell death, through increased ER stress and decreased expression of pro-survival protein, BCL-2. Transgenic mice expressing CPE-QQ did not show any difference in the processing enzyme activity of CPE compared with wild-type mice. However, the transgenic mice exhibited poor memory, depressive-like behavior, severely decreased dendrites in the hippocampal CA3 region and medial prefrontal cortex indicative of neurodegeneration, hyperphosphorylation of tau at Ser(396), and diminished neurogenesis in the dentate gyrus at 50 weeks old. All these pathologies are associated with AD and the latter with depression and were observed in 50-week-old mice. Interestingly, the younger CPE-QQ mice (11 weeks old) did not show deficits in dendrite outgrowth and neurogenesis. This study has uncovered a human CPE/NF-alpha 1 gene mutation that could lead to comorbidity of dementia and depression, emphasizing the importance of this gene in cognitive function

Observation of a new phase transition between fully and partially polarized quantum Hall states with charge and spin gaps at ν=2/3\nu = 2/3

The average electron spin-polarization $\cal P$ of two-dimensional electron gas confined in $\rm GaAs/GaAlAs$ multiple quantum-wells was measured by nuclear magnetic resonance (NMR) near the fractional quantum Hall state with filling factor $\nu={2/3}$. Above this filling factor (${{2/3}} \leq \nu < 0.85$), a strong depolarization is observed corresponding to two spin flips per additional flux quantum. The most remarkable behavior of the polarization is observed at $\nu ={{2/3}}$, where a quantum phase transition from a partially polarized (${\cal P} \approx {{3/4}}$) to a fully polarized (${\cal P} = 1$) state can be driven by increasing the ratio between the Zeeman and the Coulomb energy above a critical value $\eta_{c} = \frac{\Delta_{Z}}{\Delta_{C}} = 0.0185$.Comment: 4 pages including 4 figure