Stabilization of dipole solitons in nonlocal nonlinear media

We address the stabilization of dipole solitons in nonlocal nonlinear materials by two different approaches. First, we study the properties of such solitons in thermal nonlinear media, where the refractive index landscapes induced by laser beams strongly depend on the boundary conditions and on the sample geometry. We show how the sample geometry impacts the stability of higher-order solitons in thermal nonlinear media and reveal that dipole solitons can be made dynami-cally stable in rectangular geometries in contrast to their counterparts in thermal samples with square cross-section. Second, we discuss the impact of the saturation of the nonlocal nonlinear response on the properties of multipole solitons. We find that the saturable response also stabi-lizes dipole solitons even in symmetric geometries, provided that the input power exceeds a criti-cal value.Comment: 29 pages, 8 figures, to appear in Phys. Rev.

Vortex soliton tori with multiple nested phase singularities in dissipative media

We show the existence of stable two- and three-dimensional vortex solitons carrying multiple, spatially separated, single-charge topological dislocations nested around a vortex-ring core. Such new nonlinear states are supported by elliptical gain landscapes in focusing nonlinear media with two-photon absorption. The separation between the phase dislocations is dictated mostly by the geometry of gain landscape and it only slightly changes upon variation of the gain or absorption strength.Comment: 17 pages, 5 figures, to appear in Physical Review

Approximate solutions and scaling transformations for quadratic solitons

We study quadratic solitons supported by two- and three-wave parametric interactions in chi-2 nonlinear media. Both planar and two-dimensional cases are considered. We obtain very accurate, 'almost exact', explicit analytical solutions, matching the actual bright soliton profiles, with the help of a specially-developed approach, based on analysis of the scaling properties. Additionally, we use these approximations to describe the linear tails of solitary waves which are related to the properties of the soliton bound states.Comment: 11 pages, 9 figures; submitted for publicatio

Soliton topology versus discrete symmetry in optical lattices

We address the existence of vortex solitons supported by azimuthally modulated lattices and reveal how the global lattice discrete symmetry has fundamental implications on the possible topological charges of solitons. We set a general ``charge rule'' using group-theory techniques, which holds for all lattices belonging to a given symmetry group. Focusing in the case of Bessel lattices allows us to derive also a overall stability rule for the allowed vortex solitons.Comment: 4 pages, 3 figures. To appear in Phys. Rev. Let

Enhanced soliton interactions by inhomogeneous nonlocality and nonlinearity

We address the interactions between optical solitons in the system with longitudinally varying nonlocality degree and nonlinearity strength. We consider a physical model describing light propagation in nematic liquid crystals featuring a strongly nonlocal nonlinear response. We reveal that the variation of the nonlocality and nonlinearity along the propagation direction can substantially enhance or weaken the interaction between out-of-phase solitons. This phenomenon manifests itself as a slowdown or acceleration of the soliton collision dynamics in one-dimensional geometries or of the soliton spiraling rate in bulk media. Therefore, one finds that by engineering the nonlocality and nonlinearity variation rate one can control the output soliton location.Comment: 22 pages, 5 figures, to appear in Physical Review

Changes in serotypes causing invasive pneumococcal disease (2005–2007 vs. 1997–1999) in children under 2 years of age in a population with intermediate coverage of the 7-valent pneumococcal conjugated vaccine

AbstractSerotypes causing invasive pneumococcal disease (IPD) in children aged <2 years in Catalonia (Spain) before and after licensing of the 7-valent pneumococcal conjugated vaccine (7vPCV) were assessed, using samples taken during 1997–1999 and 2005–2007 respectively. The distribution of serotypes causing IPD within these groups was obtained by serotyping strains sent by 22 Catalan hospitals to the Carlos III Health Institute, Madrid. Between 1997–99 and 2005–2007, the proportion of vaccine serotypes causing IPD in Catalonia fell from 70.54% to 31.67% (p <0.0001). The proportion of vaccine-related serotypes, mainly serotype 19A, increased from 9.82% to 32.50% (p <0.0001). The proportion of non-vaccine, non-related serotypes (serotypes not related to vaccine serotypes) rose from 19.64% to 35.83% (p <0.05). Within this group, the proportions of serotype 24F increased significantly. There has been a change in the distribution of serotypes isolated from cases of IPD in children <2 years old in Catalonia, comprising a reduction in the proportion of 7-valent vaccine serotypes, a rise in vaccine-related serotypes, especially 19A, and a smaller rise in non-vaccine, non-related serotypes, especially serotype 24F. A new 13-valent vaccine will cover 77.91% of the serotypes causing IPD in children <2 years old in Catalonia from 2005 to 2007

Stable spatiotemporal solitons in Bessel optical lattices

We investigate the existence and stability of three-dimensional (3D) solitons supported by cylindrical Bessel lattices (BLs) in self-focusing media. If the lattice strength exceeds a threshold value, we show numerically, and using the variational approximation, that the solitons are stable within one or two intervals of values of their norm. In the latter case, the Hamiltonian-vs.-norm diagram has a "swallowtail" shape, with three cuspidal points. The model applies to Bose-Einstein condensates (BECs) and to optical media with saturable nonlinearity, suggesting new ways of making stable 3D BEC solitons and "light bullets" of an arbitrary size.Comment: 9 pages, 4 figures, Phys. Rev. Lett., in pres

Usefulness of Clinical Definitions of Influenza for Public Health Surveillance Purposes

This study investigated the performance of various case definitions and influenza symptoms in a primary healthcare sentinel surveillance system. A retrospective study of the clinical and epidemiological characteristics of the cases reported by a primary healthcare sentinel surveillance network for eleven years in Catalonia was conducted. Crude and adjusted diagnostic odds ratios (aDORs) and 95% confidence intervals (CIs) of the case definitions and symptoms for all weeks and epidemic weeks were estimated. The most predictive case definition for laboratory-confirmed influenza was the World Health Organization (WHO) case definition for ILI in all weeks (aDOR 2.69; 95% CI 2.42-2.99) and epidemic weeks (aDOR 2.20; 95% CI 1.90-2.54). The symptoms that were significant positive predictors for confirmed influenza were fever, cough, myalgia, headache, malaise, and sudden onset. Fever had the highest aDOR in all weeks (4.03; 95% CI 3.38-4.80) and epidemic weeks (2.78; 95% CI 2.21-3.50). All of the case definitions assessed performed better in patients with comorbidities than in those without. The performance of symptoms varied by age groups, with fever being of high value in older people, and cough being of high value in children. In patients with comorbidities, the performance of fever was the highest (aDOR 5.45; 95% CI 3.43-8.66). No differences in the performance of the case definition or symptoms in influenza cases according to virus type were found

Topological light bullets supported by spatio-temporal gain

We reveal that the competition between diffraction, cubic nonlinearity, two-photon absorption, and gain localized in both space and time results in arrest of collapse, suppression of azimuthal modula-tion instabilities for spatiotemporal wavepackets, and formation of stable three-dimensional light bul-lets. We show that Gaussian spatiotemporal gain landscapes support bright, fundamental light bullets, while gain landscapes featuring a ring-like spatial and a Gaussian temporal shapes may support stable vortex bullets carrying topological phase dislocations.Comment: 19 pages, 5 figures, to appear in Physical Review