Foreign language teacher’s competence in using information and communication technologies

В названии статьи ошибочно указано The development o

Foreign language teacher’s competence in using information and communication technologies

В названии статьи ошибочно указано The development o

Modern Information and Communication Technologies in the Development of Learners’ Discourse Skills

AbstractThis paper addresses the issue of students’ discursive skills development via new modern information and communication technologies (ICT). The authors discuss the notion of discourse, define the structure of the discourse competence, and develop a nomenclature of discursive skills, which can be developed by the use of modern information and communication technologies

Modes of wording direct into indirect speech in intercultural communication

This paper aims to determine the modes of wording indirec

STRUCTURAL AND TECHNOLOGICAL ANALYSIS OF THE AIRCRAFT LIQUID-GAS SYSTEMS

Тhis article is devoted to the gas-liquid systems of the aircraft and their structural and technological analysis. The paper shows the characteristics of pipelines, considers the types of working fluids and gases and covers the range of perceived internal pressures. The paper presents the classification of pipelines of flying vehicles from the point of view of their working conditions, taking into account the perceived internal pressure. The article also shows the classification scheme of major groups and types of pipe connections and fittings. The article focuses on the scheme of permanent joints made with soldering and welding, as well as the split of mobile and fixed joints of different types. The authors study the combined connections. The authors have also developed classification schemes of aircraft piping systems that depend on the system pressure. A classification scheme of piping connections, depending on the method of connection, mobility, presence of seals is singled out. The research is ilustrated with examples of compounds of different types

Foreign language teacher’s competence in using information and communication technologies

В названии статьи ошибочно указано The development o

mRNA EXPRESSION OF SOME CHEMOKINES AND THEIR RECEPTORS IN NASAL MUCOSA OF HEALTHY PERSONS

Abstract.  Chemokines  are  a  key  factor  that ensures  the  participation  of  different  cell  types  in the  immunological  protection  of  mucosa.  In  our study  we  chose  some  chemokines  that  ensured  the chemotaxis of neutrophils (CXCL8/IL-8), eosinophils (CCL11/eotaxin,  CCL24/eotaxin-2),  monocytes  and T-lymphocytes  (CCL3/MIP-1α,  CCL4/MIP-1β, CCL5/RANTES),  as  well  as  their  receptors  (CCR1, CCR3, CCR5, CXCR1, CXCR2). mRNA expression of  chemokines  and  their  receptors  in  nasopharyngeal mucosa brush-biopsy specimens determined by RT-PCR in healthy persons, the level of the same chemokines in serum determined by multiplex chemiluminescent assay were analyzed according to smoking. The level of mRNA expression of IL-8 (p < 0.001) and RANTES (p < 0.001) in nasopharynx brush-biopsy specimens and  serum  levels  of  IL-8  (p  <  0.0001)  of  smokers  were  significantly  lower  as  compared  with  nonsmokers. Correlation analysis showed the dependence of the chemokine synthesis on the factor of smoking: the index of smoking (pack/years) is negatively correlated with mRNA levels of IL-8 (r = -0,67 p = 0,003) and RANTES (r = -0,58, p = 0,015) in nasopharynx brush-biopsy specimens and serum concentration of IL-8 (r = -0,89, p = 0,0000002). Thus, these data offer that smokers manifested a defect of the local synthesis of RANTES and IL-8 in nasopharyngeal mucosa in combination with systemic defect of IL-8 production in peripheral blood, that can lead to chronization of bacterial infection and prolonged persistence of viral infection. (Med. Immunol., 2011, vol. 13, N 6, pp 617-622