Concomitant use of isotretinoin and lasers with implications for future guidelines: An updated systematic review

It is generally believed that intervention on skin while on isotretinoin or within 6 to 12 months after treatment can lead to prolonged healing and abnormal scarring. The objective of this systematic review is to evaluate the body of evidence on concomitant use of isotretinoin and lasers for adverse events as a consequence of treatment. A PRISMA‐compliant systematic review (Systematic Review Registration Number: CRD42017056492) of 12 electronic databases was conducted for the terms “laser” and “isotretinoin” or associated brand names from inception until June 2020. Subsequent reference search of studies meeting predefined inclusion criteria were conducted, and all articles were evaluated for bias and assigned levels of evidence to facilitate data synthesis. The search strategy produced 29 studies. Of 871 patients included in the studies of interest, 12 experienced transient adverse effects that resolved spontaneously, and only two presented with keloid formation, both from case reports. This systematic review suggests the risk associated with concomitant isotretinoin and laser use is small to absent. Further studies are needed, but these results suggest that current contraindications may be overly cautious.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163929/1/dth14022.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163929/2/dth14022_am.pd

Civic Education and Intercultural issues in Switzerland : Psychosocial dimensions of an education to "otherness"

In contemporary democratic societies that deal with cultural and linguistic diversity, education faces new challenges such as how to promote a shared knowledge and competence framework about “citizenship,” how to prepare the young generation to enter a complex world, and how to help immigrant students to integrate into the school system. Some of the European recommendations focus on the importance of promoting “intercultural education”. However, so far little is known about concrete practices and their outcomes. This paper aims at documenting and providing elements of reflections about the difficulties and contradictions faced by both teachers and students involved in pedagogical intercultural activities in Switzerland. From the results of a qualitative research based on a sociocultural perspective, identity and institutional issues of addressing “otherness” in school are discussed. It stresses the importance of a frame in order to allow elaboration and transformation of personal and emotional experiences into thinking and reflexive processes

Can we Learn through Disagreements ? A Sociocultural Perspective on Argumentative Interactions in a Pedagogical Setting in Higher Education

It has been well established by educational research that social interactions play a role in learning and development. In this paper, we draw on recent advances in a sociocultural perspective in psychology that have showed the dialogical dimension of learning, and allowed to consider social interactions as a matrix for its development rather than a variable merely “influencing” psychological processes

Gravitomagnetic Resonance Shift due to a Slowly Rotating Compact Star

The effect of a slowly rotating mass on a forced harmonic oscillator with two degrees of freedom is studied in the weak field approximation. It is found that according to the general theory of relativity there is a shift in the resonat frequency of the oscillator which depends on the density and rotational frequency of the gravitational source. The proposed shift is quite small under normal physical situations however it is estimated that for compact x-ray sources such as white dwarfs, pulsars, and neutron stars the shift is quite appreciable.Comment: 8 pages, 2 figures, Accepted for Publication in Inter. Journal of Modern Physics