UPPER AND LOWER BOUNDS FOR THE SKEW HERMITIAN RANDIC ENERGY OF STANDARD GRAPHS

Abstract Let us consider a simple graph . The energy of the graph is defined as the sum of the absolute values of the eigen values of the adjacency matrix [1] & [2]. The energy of , denoted by , is called Skew- Hermitian Randić energy, which is defined as the sum of the absolute values of its eigenvalues of , that is, [9]. The total π electron energy of conjugated hydrocarbon molecules are closely connected with graph invariant[10],[11]. Recently based on the eigen values of graph matrices various energies are computed. For a graph matrix, we can determine the eigen values based on which we can compute the energy of the graph. In this paper, we have determined the Skew-Hermitian Randic Energy of some standard graphs[13],[14],[15]

A PERSPECTIVE REVIEW ON APPLICATIONS OF NANOPARTICLE MEDIATED DRUG DELIVERY TO THE CNS

Delivery of drugs into the brain is one of the most interesting and challenging areas of research. The blood-brain barrier (BBB) is a highly selective semipermeable membrane that separates blood from the brain in the central nervous system. It acts as a barrier to protect the brain from microbes, neurotoxins and other chemical substances and also blocks the entry of many drugs into the brain. An estimated 6.8 billion people die every year from CNS diseases like Parkinson’s disease, Alzheimer’s disease, sclerosis, brain stroke, dementia and others. According to WHO, one billion people are affected worldwide, about 50 million suffer from epilepsy and 24 million suffer from Alzheimer and other dementias. This indicates the importance of the delivery of drugs into the brain for treating various neurological diseases and psychological disorders. In drug targeting, a concept was introduced by Dr. Paul Ehrlich as a ‘magic bullet’ that gave tremendous hope for the researches to deliver drugs into the brain. This review discuses about various drug targeting strategies and applications of nanotechnology in designing drug delivery systems with the ability to cross through the BBB for treating neurological diseases

Immediate Effects of Trataka on Autonomic Function in Healthy Volunteers: A Randomized Controlled study

BACKGROUND: Glaucoma is the leading cause of irreversible blindness in many countries and can affect the quality of life with moderate to severe loss. This study is to evaluate the effect of selected Yogasanas on Intraocular pressure (IOP). METHODS: A total of 100 subjects aged 21.20±2.69 years were randomly assigned into 5 asana group after satisfying inclusion and exclusion criteria. Ushtrasana (n=20), Sedhubandhasana (n=20), Dhanurasana (n=20), Shalabhasana (n=20), & Ardha Chakrasana (n=20). All 5 asana group assessed at baseline IOP, then given intervention for 30 seconds, post IOP taken with immediately after intervention and followup IOP after 2min relaxation are taken for analysis. The tonometer used to assess IOP in this study is Topcon CT-80 non-contact tonometer.All the 100 subjects completed the study successfully. RESULTS: The study showed no significant changes between the group Analysis. However significant reduction of IOP in left eye was seen in Dhanurasana and Sedhubandhasana immediately after the practice, Ushtrasana showed significant reduction of IOP in left eye after 2 minutes of practice and ardha chakrasana showed significant reduction of IOP in right eye after 2 minutes of practice. CONCLUSION: Among selected 5 asana practice Dhanurasana, Sedubandasana, Ushtrasana and Ardha chakrasana showed significant reduction in IOP. Whereas there is no significant changes observed in Shalabhasana

N‐heterocyclic carbene catalyzed photoenolization/Diels–Alder reaction of acid fluorides

The combination of light activation and N‐heterocyclic carbene (NHC) organocatalysis has enabled the use of acid fluorides as substrates in a UVA‐light‐mediated photochemical transformation previously observed only with aromatic aldehydes and ketones. Stoichiometric studies and TD‐DFT calculations support a mechanism involving the photoactivation of an ortho‐toluoyl azolium intermediate, which exhibits “ketone‐like” photochemical reactivity under UVA irradiation. Using this photo‐NHC catalysis approach, a novel photoenolization/Diels–Alder (PEDA) process was developed that leads to diverse isochroman‐1‐one derivatives

Expression of Autoreactive B Cell (B-1a) in Periodontal Health and Disease: An Immunohistochemical Study.

BACKGROUND: Autoreactive B cell (B-1a) may play a role in the pathogenesis of periodontal disease and this study was undertaken to elicit the autoimmune nature of B-1a cell in periodontal health and disease. MATERIALS AND METHODS: Thirty gingival tissue samples were collected from two groups of patients (periodontal health-Group A and periodontal disease- Group B). The tissue sections were paraffanised and processed. B-1a cell expression in connective tissue was determined using CD5+ as a marker by immunohistochemical analysis. Intensity of staining was assessed and interexaminer error was calculated by kappa analysis. The mean labeling index was statistically analysed using independent ‘t’ test. RESULTS: A good interexaminer agreement was observed between two examiners while assessing intensity. Comparison of mean labeling index between the two study groups was not statistically significant since p value was >0.01 (p value = 0.276). CONCLUSION: An increase in the number of autoreactive B-1a cells (CD5+) has been found in periodontitis as compared to healthy gingival specimens, which was found to be statistically insignificant

NAPROXEN INDUCED ERYTHEMA MULTIFORME-A RARE CASE REPORT

Erythema multiforme (EM) is a hypersensitivity reaction characterized by varying degrees of blisters and ulcerations. We report a case of 4 y old girl child born for Non-custodial parents who has a history of seizures and a known case of carbamazepine-induced SLE (Systemic Lupus Erythematosus) when treated with anti-inflammatory drugs developed EM. The offending drug was identified and withdrawn. Steroid was given as a part of symptomatic treatment. Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed groups of drugs for a variety of indications. The patient gradually improved and got discharged

Sea Water Channel for Underwater Communication

A potential underwater communication technology is water communication. Because of the limited physical scale, testing underwater data transmission in the laboratory differs from testing in a real-world water environment. Albeit fake dispersing specialists have been utilized to reproduce submerged correspondence through water channels under various correspondence climate conditions after the last many years, the comparability between test water and regular water isn’t dependable, for instance, the likeness of recurrence area qualities. It examines a number of distinct substances that precisely alter the water’s coefficients. As a reliability criterion for water recreation, the frequency range of data transmission through the test water’s water channel is then measured and compared. The findings demonstrate that the nature of the substances and the size of the particles have a significant impact on the properties of this water, and that the concentration of substances has an effect on the frequency domain portion of the water communication signal. If the water between the gaps contains a separate tx and rx module. Modules enable us to inform the onboard monitoring manager of marine scientist interactions and biomedical conditions

Estimation of Channel Performance of Satellite Communication and Frequency Reader

ABSTRACT: National Remote Sensing Center (NRSC) receives data from different remote satellites like IRS-P6, IRS-P5, Cartosat-2, Cartosat-2a, etc., and processes it depending on the user requirements. The satellite data received in X band is in a particular data format. This data has to be frame synchronized using a special hardware. The receiver hardware setup must be ready at any time to make it ready it"s performance is to be tested continuously.The frequency with which satellite data is coming is also continuously tested . In the proposed project VHDL code has been developed for BER reader with differential encoding and decoding and frequency reader. The external frequency and number of errors in satellite data will be displayed on HP display devices. This project has been implemented and tested using the ALTERA EPLDs. This needs crystal oscillators, thumb wheel switches,7 segment display etc., must be programmed as per the requirement. The hardware required for this has been implemented on the wire-warp board

Beneficial health effects of cumin (Cuminum cyminum) seeds upon incorporation as a potential feed additive in livestock and poultry: A mini-review

Cumin (Cuminum cyminum Linn) is an annual plant of the family Umbelliferae, with its use dating back to ancient times when it was cultivated for its medicinal and culinary potential. Cumin seeds could contain a wide variety of phytochemicals, including alkaloids, coumarins, anthraquinones, flavonoids, glycosides, proteins, resins, saponins, tannins, and steroids. In particular, linoleic acid, one of the unsaturated fatty acids found in abundance in cumin oleoresin, is credited with promoting good health. Many of cumin's purported biological actions in livestock and poultry have been attributed to flavonoids such as apigenin, luteolin, and glycosides. Cumin has several healthful qualities, such as antibacterial, insecticidal, anti-inflammatory, analgesic, antioxidant, anticancer, anti-diabetic, anti-platelet aggregation, hypotensive, bronchodilatory, immunological, anti-amyloidogenic, and anti-osteoporotic properties. Cumin supplementation may improve milk production and reproductive function in dairy cows by altering the feeding pattern of bacteria in the rumen, encouraging the growth of beneficial microbes, or stimulating the secretion of certain digestive enzymes. Because of the low price of cumin seed, it could be concluded that its inclusion in the diet might be beneficial to the commercial poultry industry and reduce the overall cost of egg and meat production. In recent years a rise in cumin's popularity has been seen as a result of the herbal movement spearheaded by naturopaths, yoga gurus, advocates of alternative medicine, and manufacturers of feed additives. Animal nutritionists are exploring the use of cumin for its potential to boost growth, improve nutrient usage efficiency, and reduce greenhouse gas emissions. This mini-review discusses how cumin could be used as a feed ingredient to boost productivity and ensure healthy animal reproduction