2,612 research outputs found
Branching Brownian Motion Conditioned on Particle Numbers
We study analytically the order and gap statistics of particles at time
for the one dimensional branching Brownian motion, conditioned to have a fixed
number of particles at . The dynamics of the process proceeds in continuous
time where at each time step, every particle in the system either diffuses
(with diffusion constant ), dies (with rate ) or splits into two
independent particles (with rate ). We derive exact results for the
probability distribution function of , the
distance between successive particles, conditioned on the event that there are
exactly particles in the system at a given time . We show that at large
times these conditional distributions become stationary . We show that they are characterised by an exponential tail
for large gaps in the
subcritical () phases, and a power law tail
at the critical point (), independently of and . Some of these results for the critical case
were announced in a recent letter [K. Ramola, S. N. Majumdar and G. Schehr,
Phys. Rev. Lett. 112, 210602 (2014)].Comment: 19 pages, 5 figure
Reactions to Negative Feedback: The Role of Resilience and Implications for Counterproductivity
The model of Organizational Frustration (Spector, 1978) suggests that individuals are more likely to engage in counterproductive work behaviour (CWB) after having had a negative experience at work due to the negative emotions brought on by such an experience. The King and Rothstein (2010) model of resilience suggests that the degree to which an individual self-regulates after an adverse workplace experience influences how they subsequently behave. Using vignettes, participants were told they received either positive or negative feedback regarding their job performance and were asked to fill out measures of resilience and intentions to engage in CWB. In a sample of 292, employed, male participants, it was found that behavioural self-regulation moderates the relationship between feedback type and CWB, as mediated by affect. This suggests that the more one engages in self-regulation, the less CWB they will likely engage in after having a negative reaction to an adverse workplace experience
Effect of antiretroviral therapy on some liver enzymes in HIV/AIDS breast fed and non breast fed children
The relationship and effect of antiretroviral therapy with associated hepatotoxicity were investigated in different paediatric age groups using serum alanine and aspartate transaminases (ALT and AST) and alkaline phosphates (ALP) biomarkers. The study consisted of a total of onehundred and twenty (120) participants; fifteen (15) each from different age groups of HIV infected children at baseline and three (3) months after initiation of therapy as well as a control group. Ninety three percent (93%) of the children studied acquired HIV infection through vertical transmission with seventy percent (70%) having mixed feeding as their feeding pattern. Before treatment initiation, total serum ALT and AST values (mean±S.E.M.) (25.7±4.8 and 69.6±3.6 U/L) were significantly higher (p<0.05) among the baseline than the control groups (21.1±1.9 and 17.9±3.6 U/L). After treatment, total serum transaminases and ALP values were found to besignificantly lower (p<0.05) among the treated (24.4±3.6, 38.4±5.4 and 255.5±77.5 U/L) than the baseline (25.7±4.8, 69.6±3.6 and 262.1±114.8 U/L) groups, except for the children in the least age group. This study concluded that antiretroviral drugs have effect on liver enzymes and are risk factors for developing hepatotoxicity especially in children at lower age groups. Children therefore require frequent evaluation during antiretroviral therapy even in the absence of signs and symptoms of metabolic complications.Keywords: Antiretroviral therapy, hepatotoxicity, transaminases, paediatric
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3D Thermal Model of Laser Surface Glazing for Ti6Al4V alloy
t: Ti6Al4V alloy plays a significant role in the biomedical applications such as bioimplants for its excellent biocompatibility. Its usage can be further extended by improving the surface hardness and wear resistance. In this respect, laser surface glazing (LSG), an advanced surface modification technique, is very useful which can produce thin hardened surface layer and strong metallurgical bonding. Investigation of temporal and spatial temperature distributions of laser glazed surface of materials are essential because temperature plays significant role in achieving required surface properties. Therefore, in this study, a 3D Finite element analysis has been developed to perform transient thermal analysis of LSG for Ti64 alloy. The model investigated temperature distribution, depth of modified zone and heating and cooling. The results show that the peak temperature is attained 2095 K for 300 W laser power, 0.2 mm beam width and 0.15 ms residence time. Since this temperature is above the melting point (1933 K) of Ti64 alloy, the melt depth is calculated 22.5 μm. Furthermore, from the simulation results, the average heating and cooling rates are estimated 1.19×107 Ks-1 and 2.71×106 Ks-1 respectively which indicate the presence of hard phases in the modified zone
Can we rely on public data as a source of information for cancer registry in developing countries?
Background/aims: Although a "hospital-based cancer registry" is important in improving patient care, a "population-based cancer registry" with emphasis on epidemiology is important in allocating health care resources and prioritizing public health programs. Because of its reliance on retrieved clinical and para-clinical documents, there is some limitation in registering all cancer incidents in this system, especially in developing countries. In this study we examined the possibility of using public data as a complementary source of information for recording cancers in a population-based cancer registry. Methods: Along with the annual census in rural areas, a survey was performed in Golestan province in March 2004 to identify public awareness about cancer incidents in the community. Individuals were questioned about history of cancer in their close relatives during the last two years. Those who reported cancer in their relatives were also asked to name the main organ of involvement. A similar list was retrieved from the cancer registry at the Ministry of Health in Gorgan, and cases with upper GI (esophagus and gastric) cancer diagnosis from 21 March 2002 through 20 March 2004 were selected for this study. Finally, these two lists were compared for examining accuracy of the collected data. Results: We included 137 cases in our study with rural residence and known addresses. Only 35 (25.5%) cases were reported by the relatives and among them only 20 (57.1%) relatives correctly reported the tumor location. Although we found a difference in accurate reporting of cancer incidents by year of diagnosis (more correct cases reported during the second versus the first year), the difference was not statistically significant between the two years. Conclusion: In this study, we examined the possibility of using public awareness about cancer incidents as a complementary source of information for a population-based cancer registry. We found that this approach is not ideal for reducing limitations. Therefore, we recommend a nationwide cancer registry to record all cancer-related information at the time of diagnosis. This strategy will reduce the need for performing retrospective surveys in collecting cancer-related information
Effectiveness of Reactive Power Capability of Photo Voltaic Inverters to Maintain Voltage Profile in a Residential Distribution Feeder
Large penetration of rooftop PVs has resulted in unacceptable voltage profile in many residential distribution feeders. Limiting real power injection from PVs to alleviate over voltage problem is not feasible due to loss of green power and hence corresponding revenue loss. Reactive capability of the PV inverter can be a solution to address over voltage and voltage dip problems to some extent. This paper proposes an algorithm to utilize reactive capability of PV inverters and investigate their effectiveness for voltage improvement based on R/X ratio of the feeder. The length and loading level of the feeder for a particular R/X ratio to have acceptable voltage profile is also investigated. This can be useful for suburban design and residential distribution planning. Furthermore, coordination among different PVs using residential smart meters via a substation based controller is also proposed
Determinant criteria for designing Health benefit package in selected countries
Health benefit package described as primary health interventions that provided with government using general funds for all regardless their financial ability. This study was aimed at determine appropriate pattern for Iran using comparative survey of Health benefit package in various countries. A review exploration was done, scholars was selected population of both developed and developing countries, required information was also extracted by articles, searches and reports of reliable sources and date were analyzed by SPSS, in brief. The vast majority frequencies was respectively allocated to accessibility (40.7%), cost- effectiveness (29.6%), prioritize, efficacy and cost (22.2%). most countries located in WHO African region were selected cost-effectiveness and accessibility, WHO southeast Asia region were selected, coverage, prioritize, efficacy and quality and finally most WHO Europeans region were elected effectiveness and services costs for including services in Health benefit package. According to most Health benefit package designer emphasis on criteria including accessibility and costeffectiveness, to design Health benefit package for Iran, these criteria must be noticed
Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance
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