61 research outputs found
Ultra-High Energy Cosmic Ray production in the polar cap regions of black hole magnetospheres
We develop a model of ultra-high energy cosmic ray (UHECR) production via
acceleration in a rotation-induced electric field in vacuum gaps in the
magnetospheres of supermassive black holes (BH). We show that if the poloidal
magnetic field near the BH horizon is misaligned with the BH rotation axis,
charged particles, which initially spiral into the BH hole along the equatorial
plane, penetrate into the regions above the BH "polar caps" and are ejected
with high energies to infinity. We show that in such a model acceleration of
protons near a BH of typical mass 3e8 solar masses is possible only if the
magnetic field is almost aligned with the BH rotation axis. We find that the
power of anisotropic electromagnetic emission from an UHECR source near a
supermassive BH should be at least 10-100 times larger then UHECR power of the
source. This implies that if the number of UHECR sources within the 100 Mpc
sphere is ~100, the power of electromagnetic emission which accompanies proton
acceleration in each source, erg/s, is comparable to the typical
luminosities of active galactic nuclei (AGN) in the local Universe. We also
explore the acceleration of heavy nuclei, for which the constraints on the
electromagnetic luminosity and on the alignment of magnetic field in the gap
are relaxed
FGF4 Independent Derivation of Trophoblast Stem Cells from the Common Vole
The derivation of stable multipotent trophoblast stem (TS) cell lines from preimplantation, and early postimplantation mouse embryos has been reported previously. FGF4, and its receptor FGFR2, have been identified as embryonic signaling factors responsible for the maintenance of the undifferentiated state of multipotent TS cells. Here we report the derivation of stable TS-like cell lines from the vole M. rossiaemeridionalis, in the absence of FGF4 and heparin. Vole TS-like cells are similar to murine TS cells with respect to their morphology, transcription factor gene expression and differentiation in vitro into derivatives of the trophectoderm lineage, and with respect to their ability to invade and erode host tissues, forming haemorrhagic tumours after subcutaneous injection into nude mice. Moreover, vole TS-like cells carry an inactive paternal X chromosome, indicating that they have undergone imprinted X inactivation, which is characteristic of the trophoblast lineage. Our results indicate that an alternative signaling pathway may be responsible for the establishment and stable proliferation of vole TS-like cells
Graphite capsules for accommodating indicators of the temperature and the neutron flux in irradiation units
Systems containing hydrogen peroxide at high concentration Communication 15. The 10� solubility isotherm of the ternary system Ca(OH)2-H2O2-H2O and further characterization of the solid phases
The effect of division of the anterior and posterior roots of the spinal cord on the mitotic activity of the epidermis and the rate of healing of cutaneous wounds in rats
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