961 research outputs found
Hybrid dispersion laser scanner.
Laser scanning technology is one of the most integral parts of today's scientific research, manufacturing, defense, and biomedicine. In many applications, high-speed scanning capability is essential for scanning a large area in a short time and multi-dimensional sensing of moving objects and dynamical processes with fine temporal resolution. Unfortunately, conventional laser scanners are often too slow, resulting in limited precision and utility. Here we present a new type of laser scanner that offers ∼1,000 times higher scan rates than conventional state-of-the-art scanners. This method employs spatial dispersion of temporally stretched broadband optical pulses onto the target, enabling inertia-free laser scans at unprecedented scan rates of nearly 100 MHz at 800 nm. To show our scanner's broad utility, we use it to demonstrate unique and previously difficult-to-achieve capabilities in imaging, surface vibrometry, and flow cytometry at a record 2D raster scan rate of more than 100 kHz with 27,000 resolvable points
Homeostatic synaptic plasticity: from single synapses to neural circuits.
Homeostatic synaptic plasticity remains an enigmatic form of synaptic plasticity. Increasing interest on the topic has fuelled a surge of recent studies that have identified key molecular players and the signaling pathways involved. However, the new findings also highlight our lack of knowledge concerning some of the basic properties of homeostatic synaptic plasticity. In this review we address how homeostatic mechanisms balance synaptic strengths between the presynaptic and the postsynaptic terminals and across synapses that share the same postsynaptic neuron
Exploiting Inter- and Intra-Memory Asymmetries for Data Mapping in Hybrid Tiered-Memories
Modern computing systems are embracing hybrid memory comprising of DRAM and
non-volatile memory (NVM) to combine the best properties of both memory
technologies, achieving low latency, high reliability, and high density. A
prominent characteristic of DRAM-NVM hybrid memory is that it has NVM access
latency much higher than DRAM access latency. We call this inter-memory
asymmetry. We observe that parasitic components on a long bitline are a major
source of high latency in both DRAM and NVM, and a significant factor
contributing to high-voltage operations in NVM, which impact their reliability.
We propose an architectural change, where each long bitline in DRAM and NVM is
split into two segments by an isolation transistor. One segment can be accessed
with lower latency and operating voltage than the other. By introducing tiers,
we enable non-uniform accesses within each memory type (which we call
intra-memory asymmetry), leading to performance and reliability trade-offs in
DRAM-NVM hybrid memory. We extend existing NVM-DRAM OS in three ways. First, we
exploit both inter- and intra-memory asymmetries to allocate and migrate memory
pages between the tiers in DRAM and NVM. Second, we improve the OS's page
allocation decisions by predicting the access intensity of a newly-referenced
memory page in a program and placing it to a matching tier during its initial
allocation. This minimizes page migrations during program execution, lowering
the performance overhead. Third, we propose a solution to migrate pages between
the tiers of the same memory without transferring data over the memory channel,
minimizing channel occupancy and improving performance. Our overall approach,
which we call MNEME, to enable and exploit asymmetries in DRAM-NVM hybrid
tiered memory improves both performance and reliability for both single-core
and multi-programmed workloads.Comment: 15 pages, 29 figures, accepted at ACM SIGPLAN International Symposium
on Memory Managemen
Experimental Study of Dispersion and Modulational Instability of Surface Gravity Waves on Constant Vorticity Currents
This paper examines experimentally the dispersion and stability of weakly nonlinear waves on opposing linearly vertically sheared current profiles (with constant vorticity). Measurements are compared against predictions from the unidirectional (1D + 1) constant vorticity nonlinear Schrödinger equation (the vor-NLSE) derived by Thomas et al. (Phys. Fluids, vol. 24, no. 12, 2012, 127102). The shear rate is negative in opposing currents when the magnitude of the current in the laboratory reference frame is negative (i.e. opposing the direction of wave propagation) and reduces with depth, as is most commonly encountered in nature. Compared to a uniform current with the same surface velocity, negative shear has the effect of increasing wavelength and enhancing stability. In experiments with a regular low-steepness wave, the dispersion relationship between wavelength and frequency is examined on five opposing current profiles with shear rates from 0 to −0.87 s−1. For all current profiles, the linear constant vorticity dispersion relation predicts the wavenumber to within the 95 % confidence bounds associated with estimates of shear rate and surface current velocity. The effect of shear on modulational instability was determined by the spectral evolution of a carrier wave seeded with spectral sidebands on opposing current profiles with shear rates between 0 and −0.48 s−1. Numerical solutions of the vor-NLSE are consistently found to predict sideband growth to within two standard deviations across repeated experiments, performing considerably better than its uniform-current NLSE counterpart. Similarly, the amplification of experimental wave envelopes is predicted well by numerical solutions of the vor-NLSE, and significantly over-predicted by the uniform-current NLSE
Tsunami evacuation plans for future megathrust earthquakes in Padang, Indonesia, considering stochastic earthquake scenarios
This study develops tsunami evacuation plans in Padang, Indonesia, using
a stochastic tsunami simulation method. The stochastic results are based on
multiple earthquake scenarios for different magnitudes (Mw 8.5,
8.75, and 9.0) that reflect asperity characteristics of the 1797 historical
event in the same region. The generation of the earthquake scenarios involves
probabilistic models of earthquake source parameters and stochastic synthesis
of earthquake slip distributions. In total, 300 source models are generated
to produce comprehensive tsunami evacuation plans in Padang. The tsunami
hazard assessment results show that Padang may face significant tsunamis
causing the maximum tsunami inundation height and depth of 15 and
10 m, respectively. A comprehensive tsunami evacuation plan –
including horizontal evacuation area maps, assessment of temporary shelters
considering the impact due to ground shaking and tsunami, and integrated
horizontal–vertical evacuation time maps – has been developed based on the
stochastic tsunami simulation results. The developed evacuation plans
highlight that comprehensive mitigation policies can be produced from the
stochastic tsunami simulation for future tsunamigenic events
The 2016 Kumamoto Earthquakes: Cascading Geological Hazards and Compounding Risks
A sequence of two strike-slip earthquakes occurred on April 14 and 16, 2016 in the intraplate region of Kyushu Island, Japan, apart from subduction zones, and caused significant damage and disruption to the Kumamoto region. The analyses of regional seismic catalog and available strong motion recordings reveal striking characteristics of the events, such as migrating seismicity, earthquake surface rupture, and major foreshock-mainshock earthquake sequences. To gain valuable lessons from the events, a UK Earthquake Engineering Field Investigation Team (EEFIT) was dispatched to Kumamoto, and earthquake damage surveys were conducted to relate observed earthquake characteristics to building and infrastructure damage caused by the earthquakes. The lessons learnt from the reconnaissance mission have important implications on current seismic design practice regarding the required seismic resistance of structures under multiple shocks and the seismic design of infrastructure subject to large ground deformation. The observations also highlight the consequences of cascading geological hazards on community resilience. To share the gathered damage data widely, geo-tagged photos are organized using Google Earth and the kmz file is made publicly available.The work is funded by the EPSRC grant (EP/I01778X/1) for the Earthquake Engineering Field Investigation Team (EEFIT). The financial supports for industrial members (GC, LH, LK, and RM) are provided by Arup, Mott MacDonald, and Willis
Hot new directions for quasi-Monte Carlo research in step with applications
This article provides an overview of some interfaces between the theory of
quasi-Monte Carlo (QMC) methods and applications. We summarize three QMC
theoretical settings: first order QMC methods in the unit cube and in
, and higher order QMC methods in the unit cube. One important
feature is that their error bounds can be independent of the dimension
under appropriate conditions on the function spaces. Another important feature
is that good parameters for these QMC methods can be obtained by fast efficient
algorithms even when is large. We outline three different applications and
explain how they can tap into the different QMC theory. We also discuss three
cost saving strategies that can be combined with QMC in these applications.
Many of these recent QMC theory and methods are developed not in isolation, but
in close connection with applications
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