4,133 research outputs found
Kinematics of terrestrial locomotion in harbor seals and gray seals: Importance of spinal flexion by amphibious phocids
Women's Activism in South Africa: Working Across Divides
Women's Activism in South Africa provides the most comprehensive collection of women's experiences within civil society since the 1994 transition. This book captures South African women's stories of collective activism and social change at a crucial point for the future of democracy in the country, if not the continent. Pulling together the voices of activists and scholars, South Africa's path to democracy and the assurance of gender rights emerge as a complex journey of both successes and challenges. The collection elucidates a new form of pragmatic feminism, building upon the elasticity between the state and civil society. What the cases demonstrate
is that while the state itself may not be a panacea, it still represents a key source of power and the primary locus of vital resources, including the rights of citizenship, access to basic needs, and the promise of protection from genderbased violence - all central to women's particular needs in South Africa
Vascular Injury After Whole Thoracic X-Ray Irradiation in the Rat
Purpose To study vascular injury after whole thoracic irradiation with single sublethal doses of X-rays in the rat and to develop markers that might predict the severity of injury. Methods and Materials Rats that received 5- or 10-Gy thorax-only irradiation and age-matched controls were studied at 3 days, 2 weeks, and 1, 2, 5, and 12 months. Several pulmonary vascular parameters were evaluated, including hemodynamics, vessel density, total lung angiotensin-converting enzyme activity, and right ventricular hypertrophy. Results By 1 month, the rats in the 10-Gy group had pulmonary vascular dropout, right ventricular hypertrophy, increased pulmonary vascular resistance, increased dry lung weights, and decreases in total lung angiotensin-converting enzyme activity, as well as pulmonary artery distensibility. In contrast, irradiation with 5 Gy resulted in only a modest increase in right ventricular weight and a reduction in lung angiotensin-converting enzyme activity. Conclusion In a previous investigation using the same model, we observed that recovery from radiation-induced attenuation of pulmonary vascular reactivity occurred. In the present study, we report that deterioration results in several vascular parameters for ≤1 year after 10 Gy, suggesting sustained remodeling of the pulmonary vasculature. Our data support clinically relevant injuries that appear in a time- and dose-related manner after exposure to relatively low radiation doses
Large Magnetic Fields and Motions of OH Masers in W75 N
We report on a second epoch of VLBA observations of the 1665 and 1667 MHz OH
masers in the massive star-forming region W75 N. We find evidence to confirm
the existence of very strong (~40 mG) magnetic fields near source VLA 2. The
masers near VLA 2 are dynamically distinct and include a very bright spot
apparently moving at 50 km/s relative to those around VLA 1. This fast-moving
spot may be an example of a rare class of OH masers seen in outflows in
star-forming regions. Due to the variability of these masers and the rapidity
of their motions, tracking these motions will require multiple observations
over a significantly shorter time baseline than obtained here. Proper motions
of the masers near VLA 1 are more suggestive of streaming along magnetized
shocks rather than Keplerian rotation in a disk. The motions of the easternmost
cluster of masers in W75 N (B) may be tracing slow expansion around an unseen
exciting source.Comment: 7 pages including 4 figures (2 color) & 3 tables, to appear in Ap
Uncharted waters: the unintended impacts of residual chlorine on water quality and biofilms
Disinfection residuals in drinking water protect water quality and public heath by limiting planktonic microbial regrowth during distribution. However, we do not consider the consequences and selective pressures of such residuals on the ubiquitous biofilms that persist on the vast internal surface area of drinking water distribution systems. Using a full scale experimental facility, integrated analyses were applied to determine the physical, chemical and biological impacts of different free chlorine regimes on biofilm characteristics (composition, structure and microbiome) and water quality. Unexpectedly, higher free chlorine concentrations resulted in greater water quality degredation, observable as elevated inorganic loading and greater discolouration (a major cause of water quality complaints and a mask for other failures). High-chlorine concentrations also reduced biofilm cell concentrations but selected for a distinct biofilm bacterial community and inorganic composition, presenting unique risks. The results challenge the assumption that a measurable free chlorine residual necessarily assures drinking water safety
GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia
Schizophrenia is a brain disorder associated with cognitive deficits that severely affect the patients' capacity for daily functioning. Whereas our understanding of its pathophysiology is limited, postmortem studies suggest that schizophrenia is associated with deficits of GABA-mediated synaptic transmission. A major role of GABA-mediated transmission may be producing synchronized network oscillations which are currently hypothesized to be essential for normal cognitive function. Therefore, cognitive deficits in schizophrenia may result from a GABA synapse dysfunction that disturbs neural synchrony. Here, we highlight recent studies further suggesting alterations of GABA transmission and network oscillations in schizophrenia. We also review current models for the mechanisms of GABA-mediated synchronization of neural activity, focusing on parvalbumin-positive GABA neurons, which are altered in schizophrenia and whose function has been strongly linked to the production of neural synchrony. Alterations of GABA signaling that impair gamma oscillations and, as a result, cognitive function suggest paths for novel therapeutic interventions
Adverse Health Effects of Spousal Violence Among Women Attending Saudi Arabian Primary Health-Care Clinics
This study aimed to investigate the frequency of spousal violence among Saudi women and document the related health effects and injuries, as well as their attitudes to gender and violence. Structured interviews were conducted with 200 ever-married women recruited from primary-care centres in Jeddah. Nearly half of the surveyed women (44.5%) reported ever experiencing physical violence from their spouse. Although 37 women (18.5%) had received violence-related injuries, only 6.5% had reported these injuries to a health-care provider. Victims of spousal violence had poor perceptions of their overall health, and reported pain or discomfort, antidepressant use and suicidal thoughts. Women mostly disagreed with the presented justifications for wife beating. However, the association between gender attitudes and spousal violence was not significant. The results of this study support calls for integration of education about partner violence into health care curricula to enhance the access and quality of services
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