Escrow Contract as a New Way to Ensure Obligations

The issues of regulation by the Russian legislation of escrow relations, their essence, foreign practice in the field of escrow relations are considered, the priority areas of their distribution in the Russian Federation are defined. A distinction has been made between the concepts of an escrow contract and an escrow account contract, and their differences have been determined both from each other and from existing and widespread relations in the Russian practice. The current legislation and the adopted amendments to the Civil Code governing the escrow contract as a separate civil law instrument are analyzed. The authors come to the conclusion that civil law presented a truncated version of the construction of an escrow invoice agreement, in contrast to the agreement that has become widespread in world practice (a limited list of property and escrow agents). contract, and their differences have been determined both from each other and from existing and widespread relations in the Russian practice. The current legislation and the adopted amendments to the Civil Code governing the escrow contract as a separate civil law instrument are analyzed. The authors come to the conclusion that civil law presented a truncated version of the construction of an escrow invoice agreement, in contrast to the agreement that has become widespread in world practice (a limited list of property and escrow agents)

Случай стрессиндуцированной кардиомиопатии

В последние годы в связи с широким применением ангиографии все чаще диагностируется кардиомиопатия (КМП) такотсубо (takotsubo), для которой характерны изменения ЭКГ, сходные с таковыми у больных с острым коронарным синдромом, повышение маркеров некроза сердечной мышцы и отсутствие значимого поражения КА. При вентрикулографии в типичных случаях выявляется транзиторное баллонирование верхушки левого желудочка. Патофизиологические механизмы, лежащие в основе этого заболевания, остаются до конца не выясненными, хотя многие исследователи относят его к редкой обратимой форме нейрогенной КМП. Авторами описан первый диагностированный ими случай КМП такотсубо, имеющий в целом типичные клинические и лабораторные проявления

Indap hypotensive efficacy, influence on cardiac structural and functional changes, and autoregulation of peripheral artery tonus

The aim of the study was to investigate indap hypotensive efficacy, its influence on cardiac structural and functional changes, as well as on vascular tonus autoregulation, among patients with essential arterial hypertension. The participants were 20 patients with essential hypertension, Stage I-II, aged 50,3 ± 6,7. Twenty-four-hour blood pressure monitoring, brain magnetic resonance tomography, heart ultrasonography were performed. Endothelium-dependent and independent vasodilatation of a. brachialis (AB) was measured in reactive hyperemia and nitrate administration tests. After 24-week (6 months) indap therapy, a significant decrease in blood pressure level (24-hour monitoring results) and in left ventricular myocardial mass (from 178,3 ± 49,3g to 165,7 ± 75,1 g, or by 7 %), was registered. The parameters of endothelial vasodilatatory function improved: AB diameter increase rised from 4,3 ± 2, 2 % to 7, 7 ± 4, 2 % (p = 0,002)

Indap hypotensive efficacy, influence on cardiac structural and functional changes, and autoregulation of peripheral artery tonus

The aim of the study was to investigate indap hypotensive efficacy, its influence on cardiac structural and functional changes, as well as on vascular tonus autoregulation, among patients with essential arterial hypertension. The participants were 20 patients with essential hypertension, Stage I-II, aged 50,3 ± 6,7. Twenty-four-hour blood pressure monitoring, brain magnetic resonance tomography, heart ultrasonography were performed. Endothelium-dependent and independent vasodilatation of a. brachialis (AB) was measured in reactive hyperemia and nitrate administration tests. After 24-week (6 months) indap therapy, a significant decrease in blood pressure level (24-hour monitoring results) and in left ventricular myocardial mass (from 178,3 ± 49,3g to 165,7 ± 75,1 g, or by 7 %), was registered. The parameters of endothelial vasodilatatory function improved: AB diameter increase rised from 4,3 ± 2, 2 % to 7, 7 ± 4, 2 % (p = 0,002)

ЗАВИСИМОСТЬ ШИРИНЫ ГОДИЧНЫХ КОЛЕЦ СОСНЫ ОБЫКНОВЕННОЙ ОТ ТЕМПЕРАТУР ВОЗДУХА И ПОЧВЫВ ЛЕСОСТЕПНОЙ ЗОНЕ ЮГА СИБИРИ

Paper contains analysis of Scots pine (Pinussylvestris L.) radial growth response on annual fluctuations of temperature of air and soil at different depths in the forest-steppe zone of South Siberia. Effect of temperature on the radial growth was identified and explained. It is positive in the cold (November-February) and negative in the warm season (May-October). It was shown that in different months influence of temperatures at different depths is significant. This climate response in the forest steppe zone varies depending on the local conditions of the site.Проведен анализ климатического отклика радиального прироста сосны обыкновенной (PinussylvestrisL.) на погодичные колебания температуры воздуха и почвы на разных глубинах в лесостепной зонеЮга Сибири. Выявлено и объяснено влияние температур на радиальный прирост - положительное в холодный (ноябрь-февраль) и отрицательное в теплый период (май-октябрь). Показано, что в различные месяцы более значимо влияние температур на различных глубинах.Эта климатическая реакция в лесостепной зоне различается в зависимости от локальных условий места произрастания

Enhanced external counterpulsation in acute coronary syndrome, as a part of the pre-coronary artery bypass surgery treatment

The continuous increase in the numbers of coronary heart disease (CHD) patients warrants the search for the new therapeutic approaches, which could be used when the standard methods are contraindicated or ineffective. One of the methods in CHD treatment is angiogenesis stimulation, i.e. increasing the number of coronary arteries (CA), which “substitute” the local CA defect. At the moment, there are several methods proposed for angiogenesis stimulation, among which enhanced external counterpulsation (EECP) had demonstrated clinical effectiveness. EECP is indicated in resistant and unstable angina, chronic heart failure, acute myocardial infarction, and cardiogenic shock. This non-invasive method is particularly important in patients with severe CHD and impossibility of myocardial revascularisation

Случай стрессиндуцированной кардиомиопатии

В последние годы в связи с широким применением ангиографии все чаще диагностируется кардиомиопатия (КМП) такотсубо (takotsubo), для которой характерны изменения ЭКГ, сходные с таковыми у больных с острым коронарным синдромом, повышение маркеров некроза сердечной мышцы и отсутствие значимого поражения КА. При вентрикулографии в типичных случаях выявляется транзиторное баллонирование верхушки левого желудочка. Патофизиологические механизмы, лежащие в основе этого заболевания, остаются до конца не выясненными, хотя многие исследователи относят его к редкой обратимой форме нейрогенной КМП. Авторами описан первый диагностированный ими случай КМП такотсубо, имеющий в целом типичные клинические и лабораторные проявления

ST ELEVATION ACUTE CORONARY SYNDROME IN NON-OBSTRUCTIVE LESION OF CORONARY ST ELEVATION ACUTE CORONARY SYNDROME IN NON-OBSTRUCTIVE LESION OF CORONARY ARTERIES: DATA FROM THE REGISTRY RECORD-3

Material and methods. The data used, from the acute coronary syndrome registry RECORD-3, in the emergency cardiology department of Tomsk SRI of Cardiology, together with another 51 center in Russia. Based on the absence of presence of NOCA, patients with ST elevation myocardial infarction, who had undergone coronary arteriography, were selected to two independent groups: 27 with NOCA and 571 with OCA.Results. There were no significant differences in the clinical portrait of NOCA and OCA patient. However, palpitation followed angina attack in NOCA patients. In the NOCA, there was significantly lower number of persons with diagnostically relevant raise of cardio specific enzymes. Indirectly, it points on temporary ischemia with no necrosis, or that the area of necrotic myocardium is not large. In NOCA patients, statistically more significantly were absent reciprocal ECG changes. Endpoints as mortality and novel heart failure development had tendency to statistically more significant decrease of prevalence in NOCA patients. As final diagnosis at discharge, in NOCA patients more often another diagnosis was mentioned (including unstable angina, etc.), but not myocardial infarction. The key issues in hospital management of these two groups were identical, except more often prescription of dihydropiridine calcium channel blockers to NOCA patients, and rarer prescription of antiplatelet drugs at discharge.Conclusion. Regardless the fact that prognosis in ACS with NOCA and intact arteries is better than in OCA, it is necessary to analyze thoroughly pathogenesis of the disease in every case, as in this category of patients especially, it is most heterogenic. As these patients have comorbid factors, it is necessary to select the leading one, and to intensify efforts on this factor directly

The effect of individual genetic heterozygosity on general homeostasis, heterosis and resilience in Siberian larch (Larix sibirica Ledeb.) using dendrochronology and microsatellite loci genotyping

Текст статьи не публикуется в открытом доступе в соответствии с политикой журнала.The genetic mechanisms underlying the relationship of individual heterozygosity (IndHet) with heterosis and homeostasis are not fully understood. Such an understanding, however, would have enormous value as it could be used to identify trees better adapted to environmental stress. Dendrochronology data, in particular the individual average radial increment growth of wood measured as the average tree ring width (AvTRW) and the variance of tree ring width (VarTRW) were used as proxies for heterosis (growth rate measured as AvTRW) and homeostasis (stability of the radial growth of individual trees measured as VarTRW), respectively. These traits were then used to test the hypothesis that IndHet can be used to predict heterosis and homeostasis of individual trees. Wood core and needle samples were collected from 100 trees of Siberian larch (Larix sibirica Ledeb.) across two populations located in Eastern Siberia. DNA samples were obtained from the needles of each individual tree and genotyped for eight highly polymorphic microsatellite loci. Then mean IndHet calculated based on the genotypes of eight loci for each tree was correlated with the statistical characteristics of the measured radial growth (AvTRW and VarTRW) and the individual standardized chronologies. The analysis did not reveal significant relationships between the studied parameters. In order to account for the strong dependence of the radial growth on tree age the age curves were examined. An original approach was employed to sort trees into groups based on the distance between these age curves. No relationship was found between these groups and the groups formed based on heterozygosity. However, further work with more genetic markers and increased sample sizes is needed to test this novel approach for estimating heterosis and homeostasis