125,513 research outputs found

    Aqueous Humor Outflow Structure and Function Imaging At the Bench and Bedside: A Review.

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    Anterior segment glaucoma clinical care and research has recently gained new focus because of novel imaging modalities and the advent of angle-based surgical treatments. Traditional investigation drawn to the trabecular meshwork now emphasizes the entire conventional aqueous humor outflow (AHO) pathway from the anterior chamber to the episcleral vein. AHO investigation can be divided into structural and functional assessments using different methods. The historical basis for studying the anterior segment of the eye and AHO in glaucoma is discussed. Structural studies of AHO are reviewed and include traditional pathological approaches to modern tools such as multi-model two-photon microscopy and optical coherence tomography. Functional assessment focuses on visualizing AHO itself through a variety of non-real-time and real-time techniques such as aqueous angiography. Implications of distal outflow resistance and segmental AHO are discussed with an emphasis on melding bench-side research to viable clinical applications. Through the development of an improved structure: function relationship for AHO in the anterior segment of the normal and diseased eye, a better understanding of the eye with improved therapeutics may be developed

    Supersymmetric Higgs Singlet Effects on B-Meson FCNC Observables at Large tan(beta)

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    Higgs singlet superfields are usually present in most extensions of the Minimal Supersymmetric Standard Model (MSSM) that address the mu-problem, such as the Next-to-Minimal Supersymmetric Standard Model (NMSSM) and the Minimal Nonminimal Supersymmetric Standard Model (MNSSM). Employing a gauge- and flavour-covariant effective Lagrangian formalism, we show how the singlet Higgs bosons of such theories can have significant contributions to B-meson flavour-changing neutral current (FCNC) observables for large values of tanβ>50\tan\beta \stackrel{>}{{}_\sim} 50 at the 1-loop level. Illustrative results are presented including effects on the B_s and B_d mass differences and on the rare decay Bsμ+μB_s\to\mu^+\mu^-. In particular, we find that depending on the actual value of the lightest singlet pseudoscalar mass in the NMSSM, the branching ratio for Bsμ+μB_s\to\mu^+\mu^- can be enhanced or even suppressed with respect to the Standard Model prediction by more than one order of magnitude.Comment: 28 pages, 8 figures, LaTeX. Minor updates. Version to be published in PR

    Galaxy Clusters Selected via the Sunyaev–Zel'dovich Effect in the SPTpol 100-square-degree Survey

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    We present a catalog of galaxy cluster candidates detected in 100 square degrees surveyed with the SPTpol receiver on the South Pole Telescope. The catalog contains 89 candidates detected with a signal-to-noise ratio greater than 4.6. The candidates are selected using the Sunyaev–Zel'dovich effect at 95 and 150 GHz. Using both space- and ground-based optical and infrared telescopes, we have confirmed 81 candidates as galaxy clusters. We use these follow-up images and archival images to estimate photometric redshifts for 66 galaxy clusters and spectroscopic observations to obtain redshifts for 13 systems. An additional two galaxy clusters are confirmed using the overdensity of near-infrared galaxies only and are presented without redshifts. We find that 15 candidates (18% of the total sample) are at redshift z ≥ 1.0, with a maximum confirmed redshift of z_(max) = 1.38±0.10. We expect this catalog to contain every galaxy cluster with M_(500c) > 2.6×10¹⁴M⊙h⁻¹₇₀ and z > 0.25 in the survey area. The mass threshold is approximately constant above z = 0.25, and the complete catalog has a median mass of approximately M_(500c) > 2.7×10¹⁴M⊙h⁻¹₇₀. Compared to previous SPT works, the increased depth of the millimeter-wave data (11.2 and 6.5 μK-arcmin at 95 and 150 GHz, respectively) makes it possible to find more galaxy clusters at high redshift and lower mass

    Studies related to ocean dynamics. Task 3.2: Aircraft Field Test Program to investigate the ability of remote sensing methods to measure current/wind-wave interactions

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    The feasibility of remote sensing of current flows in the ocean and the remote sensing of ocean currents by backscattering cross section techniques was studied. It was established that for capillary waves, small scale currents could be accurately measured through observation of wave kinematics. Drastic modifications of waves by changing currents were noted. The development of new methods for the measurement of capillary waves are discussed. Improvement methods to resolve data processing problems are suggested

    Limits from Weak Gravity Conjecture on Dark Energy Models

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    The weak gravity conjecture has been proposed as a criterion to distinguish the landscape from the swampland in string theory. As an application in cosmology of this conjecture, we use it to impose theoretical constraint on parameters of two types of dark energy models. Our analysis indicates that the Chaplygin-gas-type models realized in quintessence field are in the swampland, whereas the aa power-low decay model of the variable cosmological constant can be viable but the parameters are tightly constrained by the conjecture.Comment: Revtex4, 8 pages, 5 figures; References, minor corrections in content, and acknowledgement adde

    Charged and Neutral Currents in a 3-3-1 Model with Right-Handed Neutrinos

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    The charged and the neutral currents are obtained by using a formal algebraical approach (developed and applied by the author) within the exact solution of a 3-3-1 gauge model with right-handed neutrinos. The entire Standard Model phenomenology is recovered without imposing any supplemental condition, but only by choosing an adecquate set of parameters from the very beginning of the calculus. A new and rich phenomenology regarding the particles and their currents occurs as well. The appealing feature of our results resides in the exact expressions of the currents which need not the adjustment usually due to the small mixing angle ϕ\phi between neutral bosons ZZ and ZZ^{\prime} (like in the most of the papers in the literature treating the same issue). The required mixing was considered and aleready performed as an intermediate step by the solving method itself, since the physical eigenstates of those bosons were determined and then identified in the neutral currents.Comment: 14 pages, 1 Table, no figure
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