Design strategies for low embodied energy and greenhouse gases in buildings: analyses of the IEA Annex 57 case studies

This paper introduces the IEA Annex 57 case study method, consisting of a format for describing individual case studies and an evaluation matrix covering all case studies. Sample case studies are used to illustrate the method and the evaluation matrix through a first preliminary analysis. In compiling and evaluation existing, transparent case studies we have taken a stakeholder perspective. By so doing it is intended to identify fordecision makers the key issues affecting EE/EC in buildings. Analysis in this paper focuses on one of the six case study themes, building design strategies for EE/EC mitigation and references cases covering e.g. material selection, building shape, construction stage strategies and strategies to handle the trade-off between embodied and operational impacts in net-zero emission building design

Faster Rates of Molecular Sequence Evolution in Reproduction-Related Genes and in Species with Hypodermic Sperm Morphologies

Sexual selection drives the evolution of many striking behaviors and morphologies and should leave signatures of selection at loci underlying these phenotypes. However, although loci thought to be under sexual selection often evolve rapidly, few studies have contrasted rates of molecular sequence evolution at such loci across lineages with different sexual selection contexts. Furthermore, work has focused on separate sexed animals, neglecting alternative sexual systems. We investigate rates of molecular sequence evolution in hermaphroditic flatworms of the genus Macrostomum. Specifically, we compare species that exhibit contrasting sperm morphologies, strongly associated with multiple convergent shifts in the mating strategy, reflecting different sexual selection contexts. Species donating and receiving sperm in every mating have sperm with bristles, likely to prevent sperm removal. Meanwhile, species that hypodermically inject sperm lack bristles, potentially as an adaptation to the environment experienced by hypodermic sperm. Combining functional annotations from the model, Macrostomum lignano, with transcriptomes from 93 congeners, we find genus-wide faster sequence evolution in reproduction-related versus ubiquitously expressed genes, consistent with stronger sexual selection on the former. Additionally, species with hypodermic sperm morphologies had elevated molecular sequence evolution, regardless of a gene's functional annotation. These genome-wide patterns suggest reduced selection efficiency following shifts to hypodermic mating, possibly due to higher selfing rates in these species. Moreover, we find little evidence for convergent amino acid changes across species. Our work not only shows that reproduction-related genes evolve rapidly also in hermaphroditic animals, but also that well-replicated contrasts of different sexual selection contexts can reveal underappreciated genome-wide effects

Idler chirp optimization in a pulse-pumped parametric amplifier

A simple engineering rule for idler characteristic optimization in pulsed fiber optic parametric amplifiers operated in transparency is derived. The theoretical results are validated in both simulations and experiments

Obituary

Professor E. M. Alf Samuelsson from Chalmers University, Göteborg, Sweden, died on the 3rd of June 2005 at the age of 75 after a lengthy illness. Professor Samuelsson was an engineer with Professor Sven-Olof Asplund’s ConstructionCompany from 1952 to the time he joined Chalmers University in September 1954. In 1963 he completed his doctoral thesis with Professor Asplund on the subject of analysis of framedstructures by use of algebraic topology. He was beloved by students, colleagues and co-workersand was known as ‘Alf’ by all. Through his foresight and deep knowledge in many fields Alfcreated a strong group in Computational Mechanics at Chalmers University, which he led until his retirement in July 1994. Under his leadership the Department of Structural Mechanics flourished and has been widely recognized for its many scientific contributions. Alf supervised a large number of doctoral students of which nine have become professors. Alf was, formany years, the Dean of Research at Chalmers and has contributed much to the University’s development

Quasiparticle band structure of infinite hydrogen fluoride and hydrogen chloride chains

We study the quasiparticle band structure of isolated, infinite HF and HCl bent (zigzag) chains and examine the effect of the crystal field on the energy levels of the constituent monomers. The chains are one of the simplest but realistic models of the corresponding three-dimensional crystalline solids. To describe the isolated monomers and the chains, we set out from the Hartree-Fock approximation, harnessing the advanced Green's function methods "local molecular orbital algebraic diagrammatic construction" (ADC) scheme and "local crystal orbital ADC" (CO-ADC) in a strict second order approximation, ADC(2,2) and CO-ADC(2,2), respectively, to account for electron correlations. The configuration space of the periodic correlation calculations is found to converge rapidly only requiring nearest-neighbor contributions to be regarded. Although electron correlations cause a pronounced shift of the quasiparticle band structure of the chains with respect to the Hartree-Fock result, the bandwidth essentially remains unaltered in contrast to, e.g., covalently bound compounds.Comment: 11 pages, 6 figures, 6 tables, RevTeX4, corrected typoe

Chitosan polyplex mediated delivery of miRNA-124 reduces activation of microglial cells in vitro and in rat models of spinal cord injury

AbstractTraumatic injury to the central nervous system (CNS) is further complicated by an increase in secondary neuronal damage imposed by activated microglia/macrophages. MicroRNA-124 (miR-124) is responsible for mouse monocyte quiescence and reduction of their inflammatory cytokine production. We describe the formulation and ex vivo transfection of chitosan/miR-124 polyplex particles into rat microglia and the resulting reduction of reactive oxygen species (ROS) and TNF-α and lower expression of MHC-II. Upon microinjection into uninjured rat spinal cords, particles formed with Cy3-labeled control sequence RNA, were specifically internalized by OX42 positive macrophages and microglia cells. Alternatively particles injected in the peritoneum were transported by macrophages to the site of spinal cord injury 72h post injection. Microinjections of chitosan/miR-124 particles significantly reduced the number of ED-1 positive macrophages in the injured spinal cord. Taken together, these data present a potential treatment technique to reduce inflammation for a multitude of CNS neurodegenerative conditions.From the Clinical EditorThe treatment of spinal cord injury remains an unresolved problem. Secondary damage is often the result of inflammation caused by activated microglia and/or macrophages. In this article, the authors developed their formulation of chitosan/miR-124 polyplex particles and investigated their use in the suppression of neuronal inflammation. This exciting data may provide a new horizon for patients who suffer from spinal cord injury

Hydrogen bonding in infinite hydrogen fluoride and hydrogen chloride chains

Hydrogen bonding in infinite HF and HCl bent (zigzag) chains is studied using the ab initio coupled-cluster singles and doubles (CCSD) correlation method. The correlation contribution to the binding energy is decomposed in terms of nonadditive many-body interactions between the monomers in the chains, the so-called energy increments. Van der Waals constants for the two-body dispersion interaction between distant monomers in the infinite chains are extracted from this decomposition. They allow a partitioning of the correlation contribution to the binding energy into short- and long-range terms. This finding affords a significant reduction in the computational effort of ab initio calculations for solids as only the short-range part requires a sophisticated treatment whereas the long-range part can be summed immediately to infinite distances.Comment: 9 pages, 4 figures, 3 tables, RevTeX4, corrected typo

Building global water use scenarios

The Water Future and Solutions Initiative (WFaS) develops consistent, multi-model global water scenaros with the aim to analyze the water-food-energy-climate- environment nexus and identify future hotspots of water insecurity and related impacts on food and energy security. WFaS coordinates its work with on-going scenario development in the fifth assessment review of the Intergovernmental Panel on Climate Change (IPCC), which has developed climate scenarios based on the Representative Concentration pathways (RCPs) and alternative futures of societal developments described in the Shared Socio-economic Pathways (SSPs). In its 'fast-track' scenario assessment WFaS applies available multi-model ensembles of RCP climate scenarios and population, urbanization, and economic development quantifications of the SSPs. Here we interpret SSP narratives to indicate direct or indirect consequences for key water dimensions. Criical scenario assumptions are assessed for different conditions in terms of a country or regions ability to cope with water-related risks and its exposure to complex hydrologcal conditions. For this purpose a classification of hydro-economic challenges across countries has been developed. Scenario assumptions were developed for defined categories of hyro-economic development challenges and relevant features of SSPs. In this way we systematically assess qualitatively key scenario drivers required for global water models We then provide quantifications of assumptions for technological and structural changes for the industry and domestic sector. For the quantification of global scenarios of future water demand, we applied an ensemble of three global water models (H08, PCR-GLOBWB, WaterGAP). Ensemble results of global industrial water withdrawal highlight a steep increase in almost all SSP scenarios. Global amounts across the three models show a wide spread with the highest amounts reaching almost 2000 km^3 yr^-1 by 2050, more than doubled compared to the present industrial water use intensity (850 km^3 yr^-1). Increases in world population result in global domestic water withdrawals by 2050 reaching 700-1500 km^3 yr^-1 depending on scenario and water model. This is an increase of up to 250% compared to the present domestic water use intensity (400-450 km^3 yr^-1). We finally suggest improvements for future water use modelling

Water Futures and Solution - Fast Track Initiative (Final Report)

The Water Futures and Solutions Initiative (WFaS) is a cross-sector, collaborative global water project. Its objective is to apply systems analysis, develop scientific evidence and identify water-related policies and management practices, working together consistently across scales and sectors to improve human well-being through water security. The approach is a stakeholder-informed, scenario-based assessment of water resources and water demand that employs ensembles of state-of-the-art socio-economic and hydrological models, examines possible futures and tests the feasibility, sustainability and robustness of options that can be implemented today and can be sustainable and robust across a range of possible futures and associated uncertainties. This report aims at assessing the global current and future water situation